| KIF15 promotes human glioblastoma progression under the synergistic transactivation of REST and P300. | KIF15 promotes human glioblastoma progression under the synergistic transactivation of REST and P300.
Yu W, Han S, Hu S, Ru L, Hua C, Xue G, Zhang G, Lv K, Ge H, Wang M, Zheng L, Zhou J, Hou S, Teng Y, Deng W, Guo W., Free PMC Article | 10/22/2024 |
| Functional Analysis of RE1 Silencing Transcription Factor as a Putative Tumor Suppressor in Human Endometrial Cancer. | Functional Analysis of RE1 Silencing Transcription Factor as a Putative Tumor Suppressor in Human Endometrial Cancer.
Abedin Y, Minchella P, Peterson R, Gonnella F, Graham A, Cook I, Javellana M, Jewell A, Spoozak L, Nothnick WB., Free PMC Article | 09/24/2024 |
| SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing. | SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing.
Redin E, Sridhar H, Zhan YA, Pereira Mello B, Zhong H, Durani V, Sabet A, Manoj P, Linkov I, Qiu J, Koche RP, de Stanchina E, Astorkia M, Betel D, Quintanal-Villalonga Á, Rudin CM., Free PMC Article | 09/9/2024 |
| REST Promotes Autophagy in Gastric Cancer by Transcriptionally Activating FABP6 to Inhibit the Akt/mTOR Signaling Pathway. | REST Promotes Autophagy in Gastric Cancer by Transcriptionally Activating FABP6 to Inhibit the Akt/mTOR Signaling Pathway.
Luo J, Yu H, Yuan Z, Tang W, Wang C. | 07/24/2024 |
| REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-medulloblastoma. | REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-medulloblastoma.
Singh A, Cheng D, Swaminathan J, Yang Y, Zheng Y, Gordon N, Gopalakrishnan V., Free PMC Article | 06/26/2024 |
| Neuronal differentiation requires BRAT1 complex to remove REST from chromatin. | Neuronal differentiation requires BRAT1 complex to remove REST from chromatin.
Dokaneheifard S, Gomes Dos Santos H, Guiselle Valencia M, Arigela H, Edupuganti RR, Shiekhattar R., Free PMC Article | 06/12/2024 |
| Impaired neural stress resistance and loss of REST in bipolar disorder. | Impaired neural stress resistance and loss of REST in bipolar disorder.
Meyer K, Ling KH, Yeo PL, Spathopoulou A, Drake D, Choi J, Aron L, Garcia-Corral M, Ko T, Lee EA, Tam JM, Perlis RH, Church GM, Tsai LH, Yankner BA. | 06/5/2024 |
| Analysis of REST binding sites with canonical and non-canonical motifs in human cell lines. | Analysis of REST binding sites with canonical and non-canonical motifs in human cell lines.
Choi J, Lee EA., Free PMC Article | 05/2/2024 |
| A neurodegeneration checkpoint mediated by REST protects against the onset of Alzheimer's disease. | A neurodegeneration checkpoint mediated by REST protects against the onset of Alzheimer's disease.
Aron L, Qiu C, Ngian ZK, Liang M, Drake D, Choi J, Fernandez MA, Roche P, Bunting EL, Lacey EK, Hamplova SE, Yuan M, Wolfe MS, Bennett DA, Lee EA, Yankner BA., Free PMC Article | 11/10/2023 |
| REST Is Not Resting: REST/NRSF in Health and Disease. | REST Is Not Resting: REST/NRSF in Health and Disease.
Jin L, Liu Y, Wu Y, Huang Y, Zhang D., Free PMC Article | 11/1/2023 |
| Genome-wide Association Studies of REST Gene Associated Neurological Diseases/traits with Related Single Nucleotide Polymorphisms. | Genome-wide Association Studies of REST Gene Associated Neurological Diseases/traits with Related Single Nucleotide Polymorphisms.
Wang J, Roy SK, Richard SA, Xu Y., Free PMC Article | 09/21/2023 |
| Repressor Element-1 Binding Transcription Factor (REST) as a Possible Epigenetic Regulator of Neurodegeneration and MicroRNA-Based Therapeutic Strategies. | Repressor Element-1 Binding Transcription Factor (REST) as a Possible Epigenetic Regulator of Neurodegeneration and MicroRNA-Based Therapeutic Strategies.
Nassar A, Satarker S, Gurram PC, Upadhya D, Fayaz SM, Nampoothiri M., Free PMC Article | 09/6/2023 |
| REST in the Road Map of Brain Development. | REST in the Road Map of Brain Development.
Lam XJ, Maniam S, Cheah PS, Ling KH. | 09/6/2023 |
| NRSF regulates age-dependently cognitive ability and its conditional knockout in APP/PS1 mice moderately alters AD-like pathology. | NRSF regulates age-dependently cognitive ability and its conditional knockout in APP/PS1 mice moderately alters AD-like pathology.
Yang Y, Zhang X, Li D, Fang R, Wang Z, Yun D, Wang M, Wang J, Dong H, Fei Z, Li Q, Liu Z, Shen C, Fei J, Yu M, Behnisch T, Huang F. | 08/10/2023 |
| DNA methylation alterations at RE1-silencing transcription factor binding sites and their flanking regions in cancer. | DNA methylation alterations at RE1-silencing transcription factor binding sites and their flanking regions in cancer.
Vega-Benedetti AF, Loi E, Moi L, Zavattari P., Free PMC Article | 06/15/2023 |
| REST contributes to AKI-to-CKD transition through inducing ferroptosis in renal tubular epithelial cells. | REST contributes to AKI-to-CKD transition through inducing ferroptosis in renal tubular epithelial cells.
Gong S, Zhang A, Yao M, Xin W, Guan X, Qin S, Liu Y, Xiong J, Yang K, Xiong L, He T, Huang Y, Zhao J., Free PMC Article | 06/9/2023 |
| CRISPR/Cas9-based genome-wide screening of the deubiquitinase subfamily identifies USP3 as a protein stabilizer of REST blocking neuronal differentiation and promotes neuroblastoma tumorigenesis. | CRISPR/Cas9-based genome-wide screening of the deubiquitinase subfamily identifies USP3 as a protein stabilizer of REST blocking neuronal differentiation and promotes neuroblastoma tumorigenesis.
Karapurkar JK, Kim MS, Colaco JC, Suresh B, Sarodaya N, Kim DH, Park CH, Hong SH, Kim KS, Ramakrishna S., Free PMC Article | 06/2/2023 |
| REST/NRSF Silencing Modifies Neuronal Gene Expression in siRNA-Treated HeLa Cells: A Preliminary Exploration in the Search for Neuronal Biomarkers of Cervical Cancer. | REST/NRSF Silencing Modifies Neuronal Gene Expression in siRNA-Treated HeLa Cells: A Preliminary Exploration in the Search for Neuronal Biomarkers of Cervical Cancer.
Cortés-Sarabia K, Alarcón-Romero LDC, Mendoza-Catalán MÁ, Carpio-Pedroza JC, Castañeda-Saucedo E, Ortuño-Pineda C., Free PMC Article | 03/30/2023 |
| Parkinson's disease-associated 18 bp promoter variant of DJ-1 alters REST binding and regulates its expression. | Parkinson's disease-associated 18 bp promoter variant of DJ-1 alters REST binding and regulates its expression.
Pal P, Roy S, Chowdhury A, Chatterjee R, Ray K, Ray J. | 03/1/2023 |
| NRSF/REST lies at the intersection between epigenetic regulation, miRNA-mediated gene control and neurodevelopmental pathways associated with Intellectual disability (ID) and Schizophrenia. | NRSF/REST lies at the intersection between epigenetic regulation, miRNA-mediated gene control and neurodevelopmental pathways associated with Intellectual disability (ID) and Schizophrenia.
Alsaqati M, Davis BA, Wood J, Jones MM, Jones L, Westwood A, Petter O, Isles AR, Linden D, Van den Bree M, Owen M, Hall J, Harwood AJ., Free PMC Article | 10/22/2022 |
| Deletion of RE1-silencing transcription factor in striatal astrocytes exacerbates manganese-induced neurotoxicity in mice. | Deletion of RE1-silencing transcription factor in striatal astrocytes exacerbates manganese-induced neurotoxicity in mice.
Pajarillo E, Demayo M, Digman A, Nyarko-Danquah I, Son DS, Aschner M, Lee E., Free PMC Article | 08/20/2022 |
| Plasma repressor element 1-silencing transcription factor levels are decreased in patients with Alzheimer's disease. | Plasma repressor element 1-silencing transcription factor levels are decreased in patients with Alzheimer's disease.
Wei M, Ni J, Shi J, Li T, Xu X, Li C, Qin B, Fan D, Xie H, Wang Z, Wang Y, Lu T, Tian J., Free PMC Article | 06/11/2022 |
| Significant decrease of a master regulator of genes (REST/NRSF) in high-grade squamous intraepithelial lesion and cervical cancer. | Significant decrease of a master regulator of genes (REST/NRSF) in high-grade squamous intraepithelial lesion and cervical cancer.
Cortés-Sarabia K, Alarcón-Romero LDC, Flores-Alfaro E, Illades-Aguiar B, Vences-Velázquez A, Mendoza-Catalán MÁ, Navarro-Tito N, Valdés J, Moreno-Godínez ME, Ortuño-Pineda C., Free PMC Article | 05/14/2022 |
| REST promotes ETS1-dependent vascular growth in medulloblastoma. | REST promotes ETS1-dependent vascular growth in medulloblastoma.
Shaik S, Maegawa S, Haltom AR, Wang F, Xiao X, Dobson T, Sharma A, Yang Y, Swaminathan J, Kundra V, Li XN, Schadler K, Harmanci A, Xu L, Gopalakrishnan V., Free PMC Article | 04/2/2022 |
| Constitutional de novo deletion CNV encompassing REST predisposes to diffuse hyperplastic perilobar nephroblastomatosis (HPLN). | Constitutional de novo deletion CNV encompassing REST predisposes to diffuse hyperplastic perilobar nephroblastomatosis (HPLN).
Hyder Z, Fairclough A, Groom M, Getty J, Alexander E, van Veen EM, Makin G, Sethuraman C, Tang V, Evans DG, Maher ER, Woodward ER. | 02/26/2022 |