DCAF13 promotes ovarian cancer progression by activating FRAS1-mediated FAK signaling pathway. | DCAF13 promotes ovarian cancer progression by activating FRAS1-mediated FAK signaling pathway. Tang ZY, Wang XM, Xu CW, Sun QQ, Hua YX, Zhou QY, Hu HY, Liu SB, Guo YJ, Ao L, Che X, Zhang XC, Heger M, Zheng X, Liu AJ, Wang Q, Zhan ZJ, Cheng SQ, Pan WW., Free PMC Article | 10/7/2024 |
Inhibition of Integrin-Associated Kinases FAK and ILK on the In Vitro Model of Skin Wound Healing. | Inhibition of Integrin-Associated Kinases FAK and ILK on the In Vitro Model of Skin Wound Healing. Bildyug N. | 09/23/2024 |
Ethnicity-Based Variations in Focal Adhesion Kinase Signaling in Glioblastoma Gene Expression: A Study of the Puerto Rican Hispanic Population. | Ethnicity-Based Variations in Focal Adhesion Kinase Signaling in Glioblastoma Gene Expression: A Study of the Puerto Rican Hispanic Population. Porter T, Del Valle MM, Kucheryavykh L., Free PMC Article | 08/28/2024 |
Acidic preconditioning induced intracellular acid adaptation to protect renal injury via dynamic phosphorylation of focal adhesion kinase-dependent activation of sodium hydrogen exchanger 1. | Acidic preconditioning induced intracellular acid adaptation to protect renal injury via dynamic phosphorylation of focal adhesion kinase-dependent activation of sodium hydrogen exchanger 1. Chen A, Zhang J, Yan Z, Lu Y, Chen W, Sun Y, Gu Q, Li F, Yang Y, Qiu S, Lin X, Zhang D, Teng J, Fang Y, Shen B, Song N, Ding X., Free PMC Article | 08/26/2024 |
Analysis of Expression of the ANG1, CaSR and FAK Proteins in Uterine Fibroids. | Analysis of Expression of the ANG1, CaSR and FAK Proteins in Uterine Fibroids. Markowska A, de Mezer M, Kurzawa P, Bednarek W, Gryboś A, Krzyżaniak M, Markowska J, Gryboś M, Żurawski J., Free PMC Article | 08/9/2024 |
Focal Adhesion Kinase and Colony Stimulating Factors: Intestinal Homeostasis and Innate Immunity Crosstalk. | Focal Adhesion Kinase and Colony Stimulating Factors: Intestinal Homeostasis and Innate Immunity Crosstalk. Brown ND, Vomhof-DeKrey EE., Free PMC Article | 08/1/2024 |
FAK Inhibition Attenuates Corneal Fibroblast Differentiation In Vitro. | FAK Inhibition Attenuates Corneal Fibroblast Differentiation In Vitro. Yeung V, Sriram S, Tran JA, Guo X, Hutcheon AEK, Zieske JD, Karamichos D, Ciolino JB., Free PMC Article | 07/26/2024 |
FAK regulates tension transmission to the nucleus and endothelial transcriptome independent of kinase activity. | FAK regulates tension transmission to the nucleus and endothelial transcriptome independent of kinase activity. Akhter MZ, Yazbeck P, Tauseef M, Anwar M, Hossen F, Datta S, Vellingiri V, Chandra Joshi J, Toth PT, Srivastava N, Lenzini S, Zhou G, Lee J, Jain MK, Shin JW, Mehta D., Free PMC Article | 07/11/2024 |
T-plastin contributes to epithelial-mesenchymal transition in human lung cancer cells through FAK/AKT/Slug axis signaling pathway. | T-plastin contributes to epithelial-mesenchymal transition in human lung cancer cells through FAK/AKT/Slug axis signaling pathway. Park SY, Choi H, Choi SM, Wang S, Shim S, Jun W, Lee J, Chung JW., Free PMC Article | 07/5/2024 |
The dysadherin/FAK axis promotes individual cell migration in colon cancer. | The dysadherin/FAK axis promotes individual cell migration in colon cancer. Lee CJ, Jang TY, Kim JH, Lim S, Lee S, Nam JS., Free PMC Article | 06/12/2024 |
HuR-induced circ_0082319 contributes to hepatocellular carcinoma by elevating PTK2 through miR-505-3p. | HuR-induced circ_0082319 contributes to hepatocellular carcinoma by elevating PTK2 through miR-505-3p. Qin C, Liu S, Chen W, Xue D, Guo T, Wu B. | 05/9/2024 |
Effect of Focal Adhesion Kinase and Vinculin Expression on Migration Parameters of Normal and Tumor Epitheliocytes. | Effect of Focal Adhesion Kinase and Vinculin Expression on Migration Parameters of Normal and Tumor Epitheliocytes. Solomatina ES, Kovaleva AV, Tvorogova AV, Vorobjev IA, Saidova AA. | 05/7/2024 |
A decrease in integrin alpha5beta1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection. | A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection. Xue M, Xing L, Yang Y, Shao M, Liao F, Xu F, Chen Y, Wang S, Chen B, Yao C, Gu G, Tong C., Free PMC Article | 03/29/2024 |
ICAM-1 Deletion Using CRISPR/Cas9 Protects the Brain from Traumatic Brain Injury-Induced Inflammatory Leukocyte Adhesion and Transmigration Cascades by Attenuating the Paxillin/FAK-Dependent Rho GTPase Pathway. | ICAM-1 Deletion Using CRISPR/Cas9 Protects the Brain from Traumatic Brain Injury-Induced Inflammatory Leukocyte Adhesion and Transmigration Cascades by Attenuating the Paxillin/FAK-Dependent Rho GTPase Pathway. Saikia BB, Bhowmick S, Malat A, Preetha Rani MR, Thaha A, Abdul-Muneer PM., Free PMC Article | 03/21/2024 |
FAK mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation by modulating mitochondrial transcription termination factor 1/cyclin D1. | FAK mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation by modulating mitochondrial transcription termination factor 1/cyclin D1. Lin C, Yang H, Luo Q, Liu Q., Free PMC Article | 03/19/2024 |
ING3 inhibits the malignant progression of lung adenocarcinoma by negatively regulating ITGB4 expression to inactivate Src/FAK signaling. | ING3 inhibits the malignant progression of lung adenocarcinoma by negatively regulating ITGB4 expression to inactivate Src/FAK signaling. Cheng S, Li M, Zheng W, Li C, Hao Z, Dai Y, Wang J, Zhuo J, Zhang L. | 03/14/2024 |
THSD1 Suppresses Autophagy-Mediated Focal Adhesion Turnover by Modulating the FAK-Beclin 1 Pathway. | THSD1 Suppresses Autophagy-Mediated Focal Adhesion Turnover by Modulating the FAK-Beclin 1 Pathway. Xu Z, Lu J, Gao S, Rui YN., Free PMC Article | 03/13/2024 |
Exploring the therapeutic potential of focal adhesion kinase inhibition in overcoming chemoresistance in pancreatic ductal adenocarcinoma. | Exploring the therapeutic potential of focal adhesion kinase inhibition in overcoming chemoresistance in pancreatic ductal adenocarcinoma. Scianò F, Terrana F, Pecoraro C, Parrino B, Cascioferro S, Diana P, Giovannetti E, Carbone D. | 02/5/2024 |
DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-alpha5beta1/FAK/AKT signaling. | DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling. Liu C, Xu J, Fan J, Liu C, Xie W, Kong H. | 02/4/2024 |
ZDHHC5-mediated S-palmitoylation of FAK promotes its membrane localization and epithelial-mesenchymal transition in glioma. | ZDHHC5-mediated S-palmitoylation of FAK promotes its membrane localization and epithelial-mesenchymal transition in glioma. Wang Y, Shen N, Yang Y, Xia Y, Zhang W, Lu Y, Wang Z, Yang Z, Wang Z., Free PMC Article | 01/30/2024 |
VPS35 promotes gastric cancer progression through integrin/FAK/SRC signalling-mediated IL-6/STAT3 pathway activation in a YAP-dependent manner. | VPS35 promotes gastric cancer progression through integrin/FAK/SRC signalling-mediated IL-6/STAT3 pathway activation in a YAP-dependent manner. Zhou Q, Qi F, Zhou C, Ji J, Jiang J, Wang C, Zhao Q, Jin Y, Wu J, Cai Q, Tian H, Zhang J., Free PMC Article | 01/15/2024 |
High frequency of alternative splicing variants of the oncogene Focal Adhesion Kinase in neuroendocrine tumors of the pancreas and breast. | High frequency of alternative splicing variants of the oncogene Focal Adhesion Kinase in neuroendocrine tumors of the pancreas and breast. Xie D, Wang Z, Sun B, Qu L, Zeng M, Feng L, Guo M, Wang G, Hao J, Zhou G. | 12/22/2023 |
FAK scaffolds immune escape in pancreatic cancer. | FAK scaffolds immune escape in pancreatic cancer. Blanco-Gomez A, Jorgensen C. | 12/20/2023 |
FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer. | FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer. Canel M, Sławińska AD, Lonergan DW, Kallor AA, Upstill-Goddard R, Davidson C, von Kriegsheim A, Biankin AV, Byron A, Alfaro J, Serrels A., Free PMC Article | 12/20/2023 |
PTK2-associated gene signature could predict the prognosis of IPF. | PTK2-associated gene signature could predict the prognosis of IPF. Feng A, Caro YM, Gardner C, Grischo G, Liang Y, Wickremasinghe PD, Polmann M, Kala M, Marlowe T, Black SM, Knox KS, Wang T., Free PMC Article | 12/15/2023 |