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    Zbtb20 zinc finger and BTB domain containing 20 [ Mus musculus (house mouse) ]

    Gene ID: 56490, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    ZBTB20 Regulates SERCA2a Activity and Myocardial Contractility Through Phospholamban.

    ZBTB20 Regulates SERCA2a Activity and Myocardial Contractility Through Phospholamban.
    Ren AJ, Wei C, Liu YJ, Liu M, Wang P, Fan J, Wang K, Zhang S, Qin Z, Ren QX, Zheng Y, Chen YX, Xie Z, Gao L, Zhu Y, Zhang Y, Yang HT, Zhang WJ.

    02/12/2024
    ZBTB20 is essential for cochlear maturation and hearing in mice.

    ZBTB20 is essential for cochlear maturation and hearing in mice.
    Xie Z, Ma XH, Bai QF, Tang J, Sun JH, Jiang F, Guo W, Wang CM, Yang R, Wen YC, Wang FY, Chen YX, Zhang H, He DZ, Kelley MW, Yang S, Zhang WJ., Free PMC Article

    06/9/2023
    ZBTB20 Regulates Prolactin Expression and Lactotrope Function in Adult Mice.

    ZBTB20 Regulates Prolactin Expression and Lactotrope Function in Adult Mice.
    Han Q, Yan X, Ye Y, Han L, Ma X, Wang T, Cao D, Zhang WJ.

    11/19/2022
    ZBTB20 regulates cardiac allograft rejection through NFsmall ka, CyrillicB-mediated inflammation in mouse heart transplantation.

    ZBTB20 regulates cardiac allograft rejection through NFкB-mediated inflammation in mouse heart transplantation.
    Lu L, Shi M, Qiu J, Shi Z, Wang C, Fu Y, Lin C, Zhang L, Tao J, Liu C, Wei F, Liang S, Zheng J.

    08/27/2022
    Zbtb20 identifies and controls a thymus-derived population of regulatory T cells that play a role in intestinal homeostasis.

    Zbtb20 identifies and controls a thymus-derived population of regulatory T cells that play a role in intestinal homeostasis.
    Krzyzanowska AK, Haynes Ii RAH, Kovalovsky D, Lin HC, Osorio L, Edelblum KL, Corcoran LM, Rabson AB, Denzin LK, Sant'Angelo DB., Free PMC Article

    05/14/2022
    The zinc finger and BTB domain containing protein ZBTB20 regulates plasma triglyceride metabolism by repressing lipoprotein lipase gene transcription in hepatocytes.

    The zinc finger and BTB domain containing protein ZBTB20 regulates plasma triglyceride metabolism by repressing lipoprotein lipase gene transcription in hepatocytes.
    Li H, Liu G, Wan X, Zhou L, Qin ZB, Ma XH, Su K, Liu YJ, Yuan J, Wei CC, Ren AJ, Chen YX, Young SG, Zhang H, Xie Z, Zhang WJ., Free PMC Article

    04/30/2022
    An epigenetic circuit controls neurogenic programs during neocortex development.

    An epigenetic circuit controls neurogenic programs during neocortex development.
    Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y.

    02/12/2022
    ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.

    ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.
    Medeiros de Araújo JA, Barão S, Mateos-White I, Espinosa A, Costa MR, Gil-Sanz C, Müller U., Free PMC Article

    10/30/2021
    Zinc Finger Protein ZBTB20 protects against cardiac remodelling post-myocardial infarction via ROS-TNFalpha/ASK1/JNK pathway regulation.

    Zinc Finger Protein ZBTB20 protects against cardiac remodelling post-myocardial infarction via ROS-TNFα/ASK1/JNK pathway regulation.
    Li F, Yang Y, Xue C, Tan M, Xu L, Gao J, Xu L, Zong J, Qian W., Free PMC Article

    06/26/2021
    Zbtb20 deficiency causes cardiac contractile dysfunction in mice.

    Zbtb20 deficiency causes cardiac contractile dysfunction in mice.
    Ren AJ, Chen C, Zhang S, Liu M, Wei C, Wang K, Ma X, Song Y, Wang R, Zhang H, Chen YX, Wu H, Xie Z, Zhang Y, Zhang WJ.

    05/1/2021
    Zbtb20 Restrains CD8 T Cell Immunometabolism and Restricts Memory Differentiation and Antitumor Immunity.

    Zbtb20 Restrains CD8 T Cell Immunometabolism and Restricts Memory Differentiation and Antitumor Immunity.
    Sun Y, Preiss NK, Valenteros KB, Kamal Y, Usherwood YK, Frost HR, Usherwood EJ., Free PMC Article

    04/17/2021
    SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20.

    SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20.
    Ripamonti S, Shomroni O, Rhee JS, Chowdhury K, Jahn O, Hellmann KP, Bonn S, Brose N, Tirard M.

    02/13/2021
    ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses.

    ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses.
    Qiu J , Peng P , Xin M , Wen Z , Chen Z , Lin S , Kuang M , Fu Y , Fang G , Li S , Li C , Mao J , Qin L , Ding Y .

    01/23/2021
    data point to ZBTB20 as a critical regulator of EGFR expression and hepatocyte proliferation in mouse liver regeneration, and may serve as a potential therapeutic target in clinical settings of liver regeneration.

    ZBTB20 regulates EGFR expression and hepatocyte proliferation in mouse liver regeneration.
    Zhang H, Shi JH, Jiang H, Wang K, Lu JY, Jiang X, Ma X, Chen YX, Ren AJ, Zheng J, Xie Z, Guo S, Xu X, Zhang WJ., Free PMC Article

    11/9/2019
    these results highlight the important role of the transcription factor Zbtb20 as a temporal regulator of neurogenesis or gliogenesis, depending on the developmental context.

    Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain Injury.
    Doeppner TR, Herz J, Bähr M, Tonchev AB, Stoykova A.

    04/6/2019
    ZBTB20 is an essential regulator of hepatic lipogenesis.

    Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20.
    Liu G, Zhou L, Zhang H, Chen R, Zhang Y, Li L, Lu JY, Jiang H, Liu D, Qi S, Jiang YM, Yin K, Xie Z, Shi Y, Liu Y, Cao X, Chen YX, Zou D, Zhang WJ., Free PMC Article

    11/10/2018
    These findings reveal Zbtb20 as a novel temporal regulator for the generation of layer-specific neuronal identities.

    Zbtb20 modulates the sequential generation of neuronal layers in developing cortex.
    Tonchev AB, Tuoc TC, Rosenthal EH, Studer M, Stoykova A., Free PMC Article

    11/11/2017
    ZBTB20, an important transcriptional factor in pituitary development, is mainly responsible for the terminal differentiation of prolactin-secreting cells, thereby regulating the secretion of the pituitary hormones

    Effect of transcription factor ZBTB20 on mouse pituitary development.
    Dong Q, Chen XY, Li GM.

    10/22/2016
    Data indicate that transcription factor ZBTB20 is essential for lactotrope lineage specification.

    ZBTB20 is required for anterior pituitary development and lactotrope specification.
    Cao D, Ma X, Cai J, Luan J, Liu AJ, Yang R, Cao Y, Zhu X, Zhang H, Chen YX, Shi Y, Shi GX, Zou D, Cao X, Grusby MJ, Xie Z, Zhang WJ., Free PMC Article

    09/10/2016
    Zbtb20 regulates astrocyte specification in the mouse neocortex.

    Zbtb20 promotes astrocytogenesis during neocortical development.
    Nagao M, Ogata T, Sawada Y, Gotoh Y., Free PMC Article

    08/6/2016
    Mutation of the core sequence in this site fully abolished its binding to ZBTB20 in vitro, as well as the repression of AFP promoter activity by ZBTB20.

    ZBTB20 is a sequence-specific transcriptional repressor of alpha-fetoprotein gene.
    Zhang H, Cao D, Zhou L, Zhang Y, Guo X, Li H, Chen Y, Spear BT, Wu JW, Xie Z, Zhang WJ., Free PMC Article

    07/30/2016
    ZBTB20 regulates nociception and pain sensation by modulating TRPV1, TRPA1 and TRPM8 expression in nociceptive sensory neurons.

    ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons.
    Ren AJ, Wang K, Zhang H, Liu A, Ma X, Liang Q, Cao D, Wood JN, He DZ, Ding YQ, Yuan WJ, Xie Z, Zhang WJ., Free PMC Article

    10/31/2015
    Specific deficiency of Plzf paralog, Zbtb20, in Sertoli cells does not affect spermatogenesis and fertility in mice

    Specific deficiency of Plzf paralog, Zbtb20, in Sertoli cells does not affect spermatogenesis and fertility in mice.
    Jiang X, Zhang H, Yin S, Zhang Y, Yang W, Zheng W, Wang L, Wang Z, Bukhari I, Cooke HJ, Iqbal F, Shi Q., Free PMC Article

    10/24/2015
    Zbtb20 regulates the terminal differentiation of hypertrophic chondrocytes via repression of Sox9.

    Zbtb20 regulates the terminal differentiation of hypertrophic chondrocytes via repression of Sox9.
    Zhou G, Jiang X, Zhang H, Lu Y, Liu A, Ma X, Yang G, Yang R, Shen H, Zheng J, Hu Y, Yang X, Zhang WJ, Xie Z.

    03/21/2015
    ZBTB20 is involved in liver regeneration after partial hepatectomy in mouse.

    ZBTB20 is involved in liver regeneration after partial hepatectomy in mouse.
    Weng MZ, Zhuang PY, Hei ZY, Lin PY, Chen ZS, Liu YB, Quan ZW, Tang ZH.

    12/20/2014
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