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    STK31 serine/threonine kinase 31 [ Homo sapiens (human) ]

    Gene ID: 56164, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Spastic Paraplegia 20 and Serine/Threonine Protein Kinase 31 Expression for the Detection of Colorectal Cancer.

    Spastic Paraplegia 20 and Serine/Threonine Protein Kinase 31 Expression for the Detection of Colorectal Cancer.
    Hassan NA, Idriss NK, Gaber N, Ibrahim A, Tawfeek MA, Mossad E, Mosa AA, Ahmed EH, Sayed SA, Ahmed HA, Mohamed AAM.

    04/23/2022
    STK31 upregulation is associated with chromatin remodeling in gastric cancer and induction of tumorigenicity in a xenograft mouse model.

    STK31 upregulation is associated with chromatin remodeling in gastric cancer and induction of tumorigenicity in a xenograft mouse model.
    Bae DH, Kim HJ, Yoon BH, Park JL, Kim M, Kim SK, Kim SY, Lee SI, Song KS, Kim YS., Free PMC Article

    10/30/2021
    Higher miR-543 levels correlate with lower STK31 expression and longer pancreatic cancer survival.

    Higher miR-543 levels correlate with lower STK31 expression and longer pancreatic cancer survival.
    Yuan W, Gao H, Wang G, Miao Y, Jiang K, Zhang K, Wu J., Free PMC Article

    08/7/2021
    STK31 regulates the proliferation and cell cycle of lung cancer cells via the Wnt/betacatenin pathway and feedback regulation by cmyc.

    STK31 regulates the proliferation and cell cycle of lung cancer cells via the Wnt/β‑catenin pathway and feedback regulation by c‑myc.
    Xiong J, Xing S, Dong Z, Niu L, Xu Q, Liu P, Yang P., Free PMC Article

    08/22/2020
    FBLN1 and STK31 can be possible screening and differentiating biomarkers of colorectal cancer

    Serum FBLN1 and STK31 as biomarkers of colorectal cancer and their ability to noninvasively differentiate colorectal cancer from benign polyps.
    Watany MM, Elmashad NM, Badawi R, Hawash N.

    10/6/2018
    Relative STK31 expression level was significantly higher in patients with lymph node metastasis. STK31 expression levels in primary tumorous tissues of metastatic patients were significantly higher than in ANCTs and in lymph nodes samples, both at the RNA level and the protein level.

    STK31 as novel biomarker of metastatic potential and tumorigenicity of colorectal cancer.
    Zhong L, Liu J, Hu Y, Wang W, Xu F, Xu W, Han J, Biskup E., Free PMC Article

    03/24/2018
    Study demonstrates that, except the testes, STK31 is not expressed in normal tissues but aberrantly expressed in pancreatic cancer (PC) tissues, indicating that STK31 is a cancer-testis (CT) gene in PC. STK31 is reactivated by demethylation and, significantly higher in relapsed patients, or patients with advanced pathologic stage or poorer prognosis, suggesting that STK31 might be of potential clinical value.

    The clinical value, regulatory mechanisms, and gene network of the cancer-testis gene STK31 in pancreatic cancer.
    Zhang K, Lu Z, Zhu Y, Tian L, Zhang J, Xi C, Gao W, Jiang K, Miao Y., Free PMC Article

    03/10/2018
    The human papillomavirus type 16 oncogene E7 may affect STK31 expression through a DNA methylation-mediated mechanism.

    Serine/threonine kinases 31(STK31) may be a novel cellular target gene for the HPV16 oncogene E7 with potential as a DNA hypomethylation biomarker in cervical cancer.
    Yin FF, Wang N, Bi XN, Yu X, Xu XH, Wang YL, Zhao CQ, Luo B, Wang YK., Free PMC Article

    12/17/2016
    the aberrant expression of STK31 contributes to tumorigenicity in somatic cancer cells

    STK31 is a cell-cycle regulated protein that contributes to the tumorigenicity of epithelial cancer cells.
    Kuo PL, Huang YL, Hsieh CC, Lee JC, Lin BW, Hung LY., Free PMC Article

    11/22/2014
    High STK31 expression is associated with colon cancer.

    STK31 maintains the undifferentiated state of colon cancer cells.
    Fok KL, Chung CM, Yi SQ, Jiang X, Sun X, Chen H, Chen YC, Kung HF, Tao Q, Diao R, Chan H, Zhang XH, Chung YW, Cai Z, Chang Chan H.

    01/26/2013
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
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