| Impact of Hypoxia and the Levels of Transcription Factor HIF-1alpha and JMJD1A on Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma Cell Lines. | Impact of Hypoxia and the Levels of Transcription Factor HIF-1α and JMJD1A on Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma Cell Lines.
VON Fournier A, Wilhelm C, Tirtey C, Stöth M, Kasemo TE, Hackenberg S, Scherzad A., Free PMC Article | 11/6/2024 |
| Knockout of KDM3A in MDA-MB-231 breast cancer cells inhibits tumor malignancy and promotes apoptosis. | Knockout of KDM3A in MDA-MB-231 breast cancer cells inhibits tumor malignancy and promotes apoptosis.
Han Y, Maimaiti N, Sun Y, Yao J., Free PMC Article | 02/9/2024 |
| KDM3A promotes oral squamous cell carcinoma cell proliferation and invasion via H3K9me2 demethylation-activated DCLK1. | KDM3A promotes oral squamous cell carcinoma cell proliferation and invasion via H3K9me2 demethylation-activated DCLK1.
Yang L, Zhang Q, Yang Q. | 10/22/2022 |
| Histone demethylase JHDM2A participates in the repair of arsenic-induced DNA damage in L-02 cells by regulating DDB2. | Histone demethylase JHDM2A participates in the repair of arsenic-induced DNA damage in L-02 cells by regulating DDB2.
Li C, Zhang A, Hu T, Yang Y, Tang S, Li J. | 06/18/2022 |
| Downregulation of miR-335 exhibited an oncogenic effect via promoting KDM3A/YAP1 networks in clear cell renal cell carcinoma. | Downregulation of miR-335 exhibited an oncogenic effect via promoting KDM3A/YAP1 networks in clear cell renal cell carcinoma.
Zhang W, Liu R, Zhang L, Wang C, Dong Z, Feng J, Luo M, Zhang Y, Xu Z, Lv S, Wei Q., Free PMC Article | 05/28/2022 |
| Spermatozoa retrieval in azoospermia and expression profile of JMJD1A, TNP2, and PRM2 in a subset of the Karachi population. | Spermatozoa retrieval in azoospermia and expression profile of JMJD1A, TNP2, and PRM2 in a subset of the Karachi population.
Amjad S, Mushtaq S, Rehman R, Zahid N, Munir A, Siddiqui PQR. | 05/21/2022 |
| Histone demethylase JMJD1A in cancer progression and therapeutic resistance. | Histone demethylase JMJD1A in cancer progression and therapeutic resistance.
Jeon HY, Ryu H, Pornour M, Qi J., Free PMC Article | 04/23/2022 |
| Overexpression of let-7d explains down-regulated KDM3A and ENO2 in the pathogenesis of preeclampsia. | Overexpression of let-7d explains down-regulated KDM3A and ENO2 in the pathogenesis of preeclampsia.
Xu Q, Song Y, Lu L., Free PMC Article | 02/19/2022 |
| HIF-1alpha/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury. | HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury.
Zhao M, Wang S, Zuo A, Zhang J, Wen W, Jiang W, Chen H, Liang D, Sun J, Wang M., Free PMC Article | 02/5/2022 |
| KDM3A regulates alternative splicing of cell-cycle genes following DNA damage. | KDM3A regulates alternative splicing of cell-cycle genes following DNA damage.
Baker M, Petasny M, Taqatqa N, Bentata M, Kay G, Engal E, Nevo Y, Siam A, Dahan S, Salton M., Free PMC Article | 12/18/2021 |
| KDM1A and KDM3A promote tumor growth by upregulating cell cycle-associated genes in pancreatic cancer. | KDM1A and KDM3A promote tumor growth by upregulating cell cycle-associated genes in pancreatic cancer.
Hou X, Li Q, Yang L, Yang Z, He J, Li Q, Li D., Free PMC Article | 12/4/2021 |
| microRNA-155-3p attenuates intervertebral disc degeneration via inhibition of KDM3A and HIF1alpha. | microRNA-155-3p attenuates intervertebral disc degeneration via inhibition of KDM3A and HIF1α.
Zhou X, Li J, Teng J, Liu Y, Zhang D, Liu L, Zhang W. | 10/23/2021 |
| KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1-driven and independent disease-promoting gene expression in fusion-positive Rhabdomyosarcoma. | KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1-driven and independent disease-promoting gene expression in fusion-positive Rhabdomyosarcoma.
Sobral LM, Hicks HM, Parrish JK, McCann TS, Hsieh J, Goodspeed A, Costello JC, Black JC, Jedlicka P., Free PMC Article | 09/11/2021 |
| Cooperation between ETS transcription factor ETV1 and histone demethylase JMJD1A in colorectal cancer. | Cooperation between ETS transcription factor ETV1 and histone demethylase JMJD1A in colorectal cancer.
Oh S, Song H, Freeman WM, Shin S, Janknecht R., Free PMC Article | 08/7/2021 |
| Lysine demethylase KDM3A regulates nanophotonic hyperthermia resistance generated by 2D silicene in breast cancer. | Lysine demethylase KDM3A regulates nanophotonic hyperthermia resistance generated by 2D silicene in breast cancer.
He C, Yu L, Ding L, Yao H, Chen Y, Hao Y. | 06/26/2021 |
| JmjC-KDMs KDM3A and KDM6B modulate radioresistance under hypoxic conditions in esophageal squamous cell carcinoma. | JmjC-KDMs KDM3A and KDM6B modulate radioresistance under hypoxic conditions in esophageal squamous cell carcinoma.
Macedo-Silva C, Miranda-Gonçalves V, Lameirinhas A, Lencart J, Pereira A, Lobo J, Guimarães R, Martins AT, Henrique R, Bravo I, Jerónimo C., Free PMC Article | 04/13/2021 |
| Histone demethylase JMJD1A promotes expression of DNA repair factors and radio-resistance of prostate cancer cells. | Histone demethylase JMJD1A promotes expression of DNA repair factors and radio-resistance of prostate cancer cells.
Fan L, Xu S, Zhang F, Cui X, Fazli L, Gleave M, Clark DJ, Yang A, Hussain A, Rassool F, Qi J., Free PMC Article | 04/13/2021 |
| p300-Mediated Acetylation of Histone Demethylase JMJD1A Prevents Its Degradation by Ubiquitin Ligase STUB1 and Enhances Its Activity in Prostate Cancer. | p300-Mediated Acetylation of Histone Demethylase JMJD1A Prevents Its Degradation by Ubiquitin Ligase STUB1 and Enhances Its Activity in Prostate Cancer.
Xu S, Fan L, Jeon HY, Zhang F, Cui X, Mickle MB, Peng G, Hussain A, Fazli L, Gleave ME, Dong X, Qi J., Free PMC Article | 01/9/2021 |
| Histone demethylase Jumonji domain-containing 1A inhibits proliferation and progression of gastric cancer by upregulating runt-related transcription factor 3. | Histone demethylase Jumonji domain-containing 1A inhibits proliferation and progression of gastric cancer by upregulating runt-related transcription factor 3.
Ning K, Shao Y, He Y, Wang F, Cui X, Liu F, Li D, Li F., Free PMC Article | 12/19/2020 |
| Opposite Roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer. | Opposite Roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer.
Sui Y, Li X, Oh S, Zhang B, Freeman WM, Shin S, Janknecht R., Free PMC Article | 12/5/2020 |
| PGC-1alpha monomethylation, which is dependent on oxygen availability-regulated KDM3A, plays a critical role in the regulation of mitochondrial biogenesis in brain tumor cells. | KDM3A Senses Oxygen Availability to Regulate PGC-1α-Mediated Mitochondrial Biogenesis.
Qian X, Li X, Shi Z, Bai X, Xia Y, Zheng Y, Xu D, Chen F, You Y, Fang J, Hu Z, Zhou Q, Lu Z. | 02/22/2020 |
| Acetylation of PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing-mediated upregulation of KDM3A. | Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.
Wang Z, Yang X, Liu C, Li X, Zhang B, Wang B, Zhang Y, Song C, Zhang T, Liu M, Liu B, Ren M, Jiang H, Zou J, Liu X, Zhang H, Zhu WG, Yin Y, Zhang Z, Gu W, Luo J. | 01/18/2020 |
| Levels of KDM3A were increased in human pancreatic tumor tissues and cell lines. Knockdown of KDM3A in S2-007 cells significantly reduced colony formation, invasion, and migration. Study identified KDM3A-binding sites in the DCLK1 promoter. Levels of KDM3A and DCLK1 mRNA were higher in human pancreatic ductal adenocarcinoma than nontumor pancreatic tissues and correlated with shorter survival times of patients. | The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 and Promotes Tumorigenesis in Mice.
Dandawate P, Ghosh C, Palaniyandi K, Paul S, Rawal S, Pradhan R, Sayed AAA, Choudhury S, Standing D, Subramaniam D, Padhye SB, Gunewardena S, Thomas SM, Neil MO, Tawfik O, Welch DR, Jensen RA, Maliski S, Weir S, Iwakuma T, Anant S, Dhar A., Free PMC Article | 01/4/2020 |
| JMJD1 A is a co-activator of EPO expression | Histone H3K9 demethylase JMJD1A is a co-activator of erythropoietin expression under hypoxia.
Tian Z, Yao L, Shen Y, Guo X, Duan X. | 12/7/2019 |
| KDM3A expression is correlated with YAP1 and hippo target genes in colorectal cancer patient tissues, and may serve as a potential prognosis mark. Taken together, our study reveals novel mechanisms for hippo signaling and enhancer activation, which is critical for tumorigenesis of colorectal cancer. | Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer.
Wang HY, Long QY, Tang SB, Xiao Q, Gao C, Zhao QY, Li QL, Ye M, Zhang L, Li LY, Wu M., Free PMC Article | 10/19/2019 |