| Contribution of common and rare genetic variants in CEP72 on vincristine-induced peripheral neuropathy in brain tumour patients. | Contribution of common and rare genetic variants in CEP72 on vincristine-induced peripheral neuropathy in brain tumour patients.
Klumpers MJ, Brand ACAM, Hakobjan M, Gattuso G, Schiavello E, Terenziani M, Massimino M, Gidding CEM, Guchelaar HJ, Te Loo DMWM, Coenen MJH., Free PMC Article | 06/18/2022 |
| Association between CEP72 genotype and persistent neuropathy in survivors of childhood acute lymphoblastic leukemia. | Association between CEP72 genotype and persistent neuropathy in survivors of childhood acute lymphoblastic leukemia.
Goodenough CG, Diouf B, Yang W, Sapkota Y, Finch ER, Lu L, Partin RE, Wogksch MD, Hudson MM, Robison LL, Wang Z, Jeha S, Evans WE, Ness KK., Free PMC Article | 04/16/2022 |
| Comprehensive assessments of germline deletion structural variants reveal the association between prognostic MUC4 and CEP72 deletions and immune response gene expression in colorectal cancer patients. | Comprehensive assessments of germline deletion structural variants reveal the association between prognostic MUC4 and CEP72 deletions and immune response gene expression in colorectal cancer patients.
Lin PC, Chen HO, Lee CJ, Yeh YM, Shen MR, Chiang JH., Free PMC Article | 02/5/2022 |
| Functional genetic variants in centrosome-related genes CEP72 and YWHAG confer susceptibility to gastric cancer. | Functional genetic variants in centrosome-related genes CEP72 and YWHAG confer susceptibility to gastric cancer.
Ni J, Wang J, Fu Y, Yan C, Zhu M, Jiang Y, Chen J, Ding Y, Fan X, Li G, Jin G. | 07/17/2021 |
| Association of CEP72 rs924607 TT Genotype with Vincristine-induced Peripheral Neuropathy Measured by Motor Nerve Conduction Studies.", trans "Assoziation von CEP72 rs924607TTGenotyp mit Vincristin-induzierter peripherer Neuropathie, gemessen durch Untersuchungen der motorischen Nervenleitung. | Association of CEP72 rs924607 TT Genotype with Vincristine-induced Peripheral Neuropathy Measured by Motor Nerve Conduction Studies.
Kavčič M, Zečkanović A, Jazbec J, Debeljak M. | 12/12/2020 |
| overexpression of CEP72 was associated with a sizable increase in cAMP response element-binding protein binding at the SERPINE1 promoter, leading to increased SERPINE1 transcription. | Overexpression of CEP72 Promotes Bladder Urothelial Carcinoma Cell Aggressiveness via Epigenetic CREB-Mediated Induction of SERPINE1.
Li X, Dong P, Wei W, Jiang L, Guo S, Huang C, Liu Z, Chen J, Zhou F, Xie D, Liu Z. | 03/14/2020 |
| Concerning CEP72, our results are in line with the findings from the St Jude cohort of children treated for ALL with higher vincristine doses during chronic treatment. Larger high-throughput genetic analyses may be warranted to evaluate variants in other candidate genes such as CYP3A5 and reveal new nonpreviously reported alleles that may be peculiar to this region of the world | Genetic polymorphisms in candidate genes are not associated with increased vincristine-related peripheral neuropathy in Arab children treated for acute childhood leukemia: a single institution study.
Zgheib NK, Ghanem KM, Tamim H, Aridi C, Shahine R, Tarek N, Saab R, Abboud MR, El-Solh H, Muwakkit SA. | 04/6/2019 |
| CEP72-ROS1 is a novel ROS1 fusion variant in non-small cell lung cancer (NSCLC) discovered by next-generation sequencing and could be included in ROS1 detection assay, such as reverse transcription PCR. | CEP72-ROS1: A novel ROS1 oncogenic fusion variant in lung adenocarcinoma identified by next-generation sequencing.
Zhu YC, Zhou YF, Wang WX, Xu CW, Zhuang W, Du KQ, Chen G., Free PMC Article | 12/22/2018 |
| CEP72 represents a putative oncogene in colorectal cancer that might negatively regulate the mitotic function of BRCA1 to ensure chromosomal stability | The putative oncogene CEP72 inhibits the mitotic function of BRCA1 and induces chromosomal instability.
Lüddecke S, Ertych N, Stenzinger A, Weichert W, Beissbarth T, Dyczkowski J, Gaedcke J, Valerius O, Braus GH, Kschischo M, Bastians H. | 09/2/2017 |
| The CEP72 polymorphism can identify adults at increased risk of vincristine-induced peripheral neuropathy | An Inherited Genetic Variant in CEP72 Promoter Predisposes to Vincristine-Induced Peripheral Neuropathy in Adults With Acute Lymphoblastic Leukemia.
Stock W, Diouf B, Crews KR, Pei D, Cheng C, Laumann K, Mandrekar SJ, Luger S, Advani A, Stone RM, Larson RA, Evans WE., Free PMC Article | 05/20/2017 |
| aim of this study was to determine whether the CEP72 rs924607 TT genotype is a useful marker of vincristine neuropathy during induction therapy among Spanish children with B-ALL treated on the LAL-SHOP protocols | Lack of association of the CEP72 rs924607 TT genotype with vincristine-related peripheral neuropathy during the early phase of pediatric acute lymphoblastic leukemia treatment in a Spanish population.
Gutierrez-Camino A, Martin-Guerrero I, Lopez-Lopez E, Echebarria-Barona A, Zabalza I, Ruiz I, Guerra-Merino I, Garcia-Orad A. | 09/24/2016 |
| In this study an inherited polymorphism in the promoter region of CEP72 was associated with increased risk and severity of vincristine-related peripheral neuropathy. | Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia.
Diouf B, Crews KR, Lew G, Pei D, Cheng C, Bao J, Zheng JJ, Yang W, Fan Y, Wheeler HE, Wing C, Delaney SM, Komatsu M, Paugh SW, McCorkle JR, Lu X, Winick NJ, Carroll WL, Loh ML, Hunger SP, Devidas M, Pui CH, Dolan ME, Relling MV, Evans WE., Free PMC Article | 03/21/2015 |
| Observational study and meta-analysis of gene-disease association. (HuGE Navigator) | Supervised machine learning and logistic regression identifies novel epistatic risk factors with PTPN22 for rheumatoid arthritis.
Briggs FB, Ramsay PP, Madden E, Norris JM, Holers VM, Mikuls TR, Sokka T, Seldin MF, Gregersen PK, Criswell LA, Barcellos LF., Free PMC Article | 04/7/2010 |
| Findings show that Cep72 is the key protein essential for maintaining microtubule-organizing activity and structural integrity of the centrosome. | Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation.
Oshimori N, Li X, Ohsugi M, Yamamoto T., Free PMC Article | 01/21/2010 |