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    TMEM100 transmembrane protein 100 [ Homo sapiens (human) ]

    Gene ID: 55273, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Role of TMEM100 in mechanically insensitive nociceptor un-silencing.

    Role of TMEM100 in mechanically insensitive nociceptor un-silencing.
    Nees TA, Wang N, Adamek P, Zeitzschel N, Verkest C, La Porta C, Schaefer I, Virnich J, Balkaya S, Prato V, Morelli C, Begay V, Lee YJ, Tappe-Theodor A, Lewin GR, Heppenstall PA, Taberner FJ, Lechner SG., Free PMC Article

    04/10/2023
    Upregulation of DRG protein TMEM100 facilitates dry-skin-induced pruritus by enhancing TRPA1 channel function.

    Upregulation of DRG protein TMEM100 facilitates dry-skin-induced pruritus by enhancing TRPA1 channel function.
    Pan C, Jiao Y, Kong D, Deng H, Xu S, Tang D, Yin W, Gao P, Yu W, Fan Y, Wen D., Free PMC Article

    12/17/2022
    Histone deacetylase 6-mediated downregulation of TMEM100 expedites the development and progression of non-small cell lung cancer.

    Histone deacetylase 6-mediated downregulation of TMEM100 expedites the development and progression of non-small cell lung cancer.
    Wang Y, Ha M, Li M, Zhang L, Chen Y.

    02/5/2022
    Functional expression of TRPA1 channel, TRPV1 channel and TMEM100 in human odontoblasts.

    Functional expression of TRPA1 channel, TRPV1 channel and TMEM100 in human odontoblasts.
    Liu Y, Wang Y, Lou Y, Tian W, Que K.

    01/29/2022
    TMEM100 induces cell death in nonsmall cell lung cancer via the activation of autophagy and apoptosis.

    TMEM100 induces cell death in non‑small cell lung cancer via the activation of autophagy and apoptosis.
    He Q, Dong Y, Zhu Y, Ding Z, Zhang X, Wang Z, Ai R, He Y.

    01/1/2022
    TMEM100 negatively regulated by microRNA106b facilitates cellular apoptosis by suppressing survivin expression in NSCLC.

    TMEM100 negatively regulated by microRNA‑106b facilitates cellular apoptosis by suppressing survivin expression in NSCLC.
    Ma J, Yan T, Bai Y, Ye M, Ma C, Ma X, Zhang L.

    12/4/2021
    TMEM100 expression suppresses metastasis and enhances sensitivity to chemotherapy in gastric cancer.

    TMEM100 expression suppresses metastasis and enhances sensitivity to chemotherapy in gastric cancer.
    Zhuang J, Huang Y, Zheng W, Yang S, Zhu G, Wang J, Lin X, Ye J.

    04/13/2021
    TMEM100 is critical for inflammatory cytokines secretion and is regulated by MAPK (ERK/JNK) signaling pathway in hepatic stellate cells.

    TMEM100 mediates inflammatory cytokines secretion in hepatic stellate cells and its mechanism research.
    Pan LX, Li LY, Zhou H, Cheng SQ, Liu YM, Lian PP, Li L, Wang LL, Rong SJ, Shen CP, Li J, Xu T.

    11/23/2019
    experiments using another type of ER stress inducer demonstrated that calcium signaling was more important than ER stress in the regulation of TMEM100 expression

    The expression of Transmembrane Protein 100 is regulated by alterations in calcium signaling rather than endoplasmic reticulum stress.
    Kuboyama A, Sasaki T, Shimizu M, Inoue J, Sato R.

    10/6/2018
    The current findings suggest that TMEM100 functions as a tumor suppressor in hepatocellular carcinoma metastasis and proliferation.

    Novel roles of TMEM100: inhibition metastasis and proliferation of hepatocellular carcinoma.
    Ou D, Yang H, Hua D, Xiao S, Yang L., Free PMC Article

    05/21/2016
    This study demonistrated that TMEM100 is a novel, membrane-associated marker for enteric nerves and is as effective as PGP9.5 for identifying neuronal structures in the gastrointestinal tract.

    Distribution of TMEM100 in the mouse and human gastrointestinal tract--a novel marker of enteric nerves.
    Eisenman ST, Gibbons SJ, Singh RD, Bernard CE, Wu J, Sarr MG, Kendrick ML, Larson DW, Dozois EJ, Shen KR, Farrugia G., Free PMC Article

    11/16/2013
    Loss of TMEM100 is associated with lung adenocarcinoma.

    Association of lung adenocarcinoma clinical stage with gene expression pattern in noninvolved lung tissue.
    Frullanti E, Colombo F, Falvella FS, Galvan A, Noci S, De Cecco L, Incarbone M, Alloisio M, Santambrogio L, Nosotti M, Tosi D, Pastorino U, Dragani TA.

    09/22/2012
    Observational study of gene-disease association. (HuGE Navigator)

    A common variant in DRD3 receptor is associated with autism spectrum disorder.
    de Krom M, Staal WG, Ophoff RA, Hendriks J, Buitelaar J, Franke B, de Jonge MV, Bolton P, Collier D, Curran S, van Engeland H, van Ree JM.

    01/11/2009
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