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    YTHDF1 YTH N6-methyladenosine RNA binding protein F1 [ Homo sapiens (human) ]

    Gene ID: 54915, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis.

    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis.
    Chen D, Ji F, Zhou Q, Cheung H, Pan Y, Lau HC, Liang C, Yang Z, Huang P, Wei Q, Cheung AH, Kang W, Chen H, Yu J, Wong CC., Free PMC Article

    10/25/2024
    HIF-1alpha-induced expression of the m6A reader YTHDF1 inhibits the ferroptosis of nucleus pulposus cells by promoting SLC7A11 translation.

    HIF-1α-induced expression of the m6A reader YTHDF1 inhibits the ferroptosis of nucleus pulposus cells by promoting SLC7A11 translation.
    Lu X, Li D, Lin Z, Gao T, Gong Z, Zhang Y, Wang H, Xia X, Lu F, Song J, Xu G, Jiang J, Ma X, Zou F., Free PMC Article

    10/22/2024
    YTHDF1 regulates GID8-mediated glutamine metabolism to promote colorectal cancer progression in m6A-dependent manner.

    YTHDF1 regulates GID8-mediated glutamine metabolism to promote colorectal cancer progression in m6A-dependent manner.
    Han Y, Pu Y, Liu X, Liu Z, Chen Y, Tang L, Zhou J, Song Q, Ji Q.

    09/9/2024
    YTHDF1 facilitates esophageal cancer progression via augmenting m6A-dependent TINAGL1 translation.

    YTHDF1 facilitates esophageal cancer progression via augmenting m6A-dependent TINAGL1 translation.
    Zhang L, Cai E, Xu Y, Liu Z, Zheng M, Sun Z, Pei D, Wang Q.

    08/31/2024
    YTHDF1 promotes the osteolytic bone metastasis of breast cancer via inducing EZH2 and CDH11 translation.

    YTHDF1 promotes the osteolytic bone metastasis of breast cancer via inducing EZH2 and CDH11 translation.
    Wang S, Xu L, Wang D, Zhao S, Li K, Ma F, Yao Q, Zhang Y, Wu Z, Shao Y, Song S, Yan W.

    08/1/2024
    KIAA1429 increases FOXM1 expression through YTHDF1-mediated m6A modification to promote aerobic glycolysis and tumorigenesis in multiple myeloma.

    KIAA1429 increases FOXM1 expression through YTHDF1-mediated m6A modification to promote aerobic glycolysis and tumorigenesis in multiple myeloma.
    Wu Y, Luo Y, Yao X, Shi X, Xu Z, Re J, Shi M, Li M, Liu J, He Y, Du X., Free PMC Article

    07/29/2024
    YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis.

    YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis.
    Chen J, Bai X, Zhang W, Yan Z, Liu Y, Zhou S, Wu X, He X, Yang A., Free PMC Article

    05/24/2024
    RBMS1 Coordinates with the m[6]A Reader YTHDF1 to Promote NSCLC Metastasis through Stimulating S100P Translation.

    RBMS1 Coordinates with the m(6)A Reader YTHDF1 to Promote NSCLC Metastasis through Stimulating S100P Translation.
    Sun Y, Chen D, Sun S, Ren M, Zhou L, Chen C, Zhao J, Wei H, Zhao Q, Qi Y, Zhang J, Zhang G, Liu H, Yang Q, Liu Q, Wang Y, Zhang W., Free PMC Article

    04/23/2024
    YTHDF1 promotes the viability and self-renewal of glioma stem cells by enhancing LINC00900 stability.

    YTHDF1 promotes the viability and self‑renewal of glioma stem cells by enhancing LINC00900 stability.
    Zhang Y, Zhu Y, Zhang Y, Liu Z, Zhao X., Free PMC Article

    04/5/2024
    YTHDF1-CLOCK axis contributes to pathogenesis of allergic airway inflammation through LLPS.

    YTHDF1-CLOCK axis contributes to pathogenesis of allergic airway inflammation through LLPS.
    Wang J, Zhou Y, Zhang M, Wu Y, Wu Q, Su W, Xu M, Wu J, Zhang M, Shuai J, Tang W, Lv J, Wu M, Xia Z.

    04/3/2024
    N6-Methyladenosine Reader YTHDF1 Promotes Stemness and Therapeutic Resistance in Hepatocellular Carcinoma by Enhancing NOTCH1 Expression.

    N6-Methyladenosine Reader YTHDF1 Promotes Stemness and Therapeutic Resistance in Hepatocellular Carcinoma by Enhancing NOTCH1 Expression.
    Zhang X, Su T, Wu Y, Cai Y, Wang L, Liang C, Zhou L, Wang S, Li XX, Peng S, Kuang M, Yu J, Xu L.

    03/19/2024
    YTHDF1's Regulatory Involvement in Breast Cancer Prognosis, Immunity, and the ceRNA Network.

    YTHDF1's Regulatory Involvement in Breast Cancer Prognosis, Immunity, and the ceRNA Network.
    Luo W, Zhou Y, Wang J, Wang K, Lin Q, Li Y, Xie Y, Li M, Wang J, Xiong L., Free PMC Article

    02/28/2024
    YTHDF1 enhances stemness and chemoresistance in triple-negative breast cancer cells by upregulating SIAH2.

    YTHDF1 enhances stemness and chemoresistance in triple-negative breast cancer cells by upregulating SIAH2.
    Wu A, Wang X, Zhang F, Yang X, Quan Y, Dong J, Lai Y, Yang D, Sun J, Wang M.

    02/9/2024
    N[6]-methyladenosine regulator YTHDF1 represses the CD8 + T cell-mediated antitumor immunity and ferroptosis in prostate cancer via m[6]A/PD-L1 manner.

    N(6)-methyladenosine regulator YTHDF1 represses the CD8 + T cell-mediated antitumor immunity and ferroptosis in prostate cancer via m(6)A/PD-L1 manner.
    Wang Y, Jin P, Wang X.

    02/1/2024
    METTL3/YTHDF1 m[6]A axis promotes tumorigenesis by enhancing DDR2 expression in ovarian cancer.

    METTL3/YTHDF1 m(6)A axis promotes tumorigenesis by enhancing DDR2 expression in ovarian cancer.
    Zhi D, Zhou K, Liu S, Yu W, Dong M, Yan C.

    01/29/2024
    The PIN1-YTHDF1 axis promotes breast tumorigenesis via the m[6]A-dependent stabilization of AURKA mRNA.

    The PIN1-YTHDF1 axis promotes breast tumorigenesis via the m(6)A-dependent stabilization of AURKA mRNA.
    Shrestha P, Kim G, Kang H, Bhattarai PY, Choi HS.

    01/16/2024
    M6A reader YTHDF1 promotes malignant progression of laryngeal squamous carcinoma through activating the EMT pathway by EIF4A3.

    M6A reader YTHDF1 promotes malignant progression of laryngeal squamous carcinoma through activating the EMT pathway by EIF4A3.
    Guo H, Han Q, Guan X, Li Z, Wang Y, He L, Guo Y, Zhao L, Xue X, Liu H, Zhang C.

    01/5/2024
    FMRP phosphorylation modulates neuronal translation through YTHDF1.

    FMRP phosphorylation modulates neuronal translation through YTHDF1.
    Zou Z, Wei J, Chen Y, Kang Y, Shi H, Yang F, Shi Z, Chen S, Zhou Y, Sepich-Poore C, Zhuang X, Zhou X, Jiang H, Wen Z, Jin P, Luo C, He C.,

    12/22/2023
    m[6]A modification associated with YTHDF1 is involved in Japanese encephalitis virus infection.

    m(6)A modification associated with YTHDF1 is involved in Japanese encephalitis virus infection.
    Li XH, Chen J, Ou YD, Zhong X, Hu JH, Sun RC, Lv YJ, Wei JC, Go YY, Zhou B.

    12/21/2023
    YTHDF1 mitigates acute kidney injury via safeguarding m[6]A-methylated mRNAs in stress granules of renal tubules.

    YTHDF1 mitigates acute kidney injury via safeguarding m(6)A-methylated mRNAs in stress granules of renal tubules.
    Yang W, Zhang M, Li J, Qu S, Zhou F, Liu M, Li L, Liu Z, Zen K., Free PMC Article

    10/30/2023
    H3K18 lactylation promotes the progression of arsenite-related idiopathic pulmonary fibrosis via YTHDF1/m6A/NREP.

    H3K18 lactylation promotes the progression of arsenite-related idiopathic pulmonary fibrosis via YTHDF1/m6A/NREP.
    Wang P, Xie D, Xiao T, Cheng C, Wang D, Sun J, Wu M, Yang Y, Zhang A, Liu Q.

    10/25/2023
    A novel MYCN-YTHDF1 cascade contributes to retinoblastoma tumor growth by eliciting m[6]A -dependent activation of multiple oncogenes.

    A novel MYCN-YTHDF1 cascade contributes to retinoblastoma tumor growth by eliciting m(6)A -dependent activation of multiple oncogenes.
    Luo Y, He M, Yang J, Zhang F, Chen J, Wen X, Fan J, Fan X, Chai P, Jia R.

    09/14/2023
    H19 recruited N 6 -methyladenosine (m 6 A) reader YTHDF1 to promote SCARB1 translation and facilitate angiogenesis in gastric cancer.

    H19 recruited N 6 -methyladenosine (m 6 A) reader YTHDF1 to promote SCARB1 translation and facilitate angiogenesis in gastric cancer.
    Bai R, Sun M, Chen Y, Zhuo S, Song G, Wang T, Zhang Z., Free PMC Article

    07/23/2023
    O-GlcNAcylation promotes the cytosolic localization of the m[6]A reader YTHDF1 and colorectal cancer tumorigenesis.

    O-GlcNAcylation promotes the cytosolic localization of the m(6)A reader YTHDF1 and colorectal cancer tumorigenesis.
    Li J, Ahmad M, Sang L, Zhan Y, Wang Y, Yan Y, Liu Y, Mi W, Lu M, Dai Y, Zhang R, Dong MQ, Yang YG, Wang X, Sun J, Li J., Free PMC Article

    07/6/2023
    YTHDF1 Promotes Bladder Cancer Cell Proliferation via the METTL3/YTHDF1-RPN2-PI3K/AKT/mTOR Axis.

    YTHDF1 Promotes Bladder Cancer Cell Proliferation via the METTL3/YTHDF1-RPN2-PI3K/AKT/mTOR Axis.
    Zhu J, Tong H, Sun Y, Li T, Yang G, He W., Free PMC Article

    05/5/2023
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