| Global acetylome profiling indicates EPA impedes but OA promotes prostate cancer motility through altered acetylation of PFN1 and FLNA. | Global acetylome profiling indicates EPA impedes but OA promotes prostate cancer motility through altered acetylation of PFN1 and FLNA.
He C, Chen X, Chen Y, Sun J, Qi M, Rocha S, Wang M. | 10/10/2024 |
| Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia. | Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia.
Funes S, Jung J, Gadd DH, Mosqueda M, Zhong J, Shankaracharya, Unger M, Stallworth K, Cameron D, Rotunno MS, Dawes P, Fowler-Magaw M, Keagle PJ, McDonough JA, Boopathy S, Sena-Esteves M, Nickerson JA, Lutz C, Skarnes WC, Lim ET, Schafer DP, Massi F, Landers JE, Bosco DA., Free PMC Article | 03/22/2024 |
| Actin-binding protein profilin1 is an important determinant of cellular phosphoinositide control. | Actin-binding protein profilin1 is an important determinant of cellular phosphoinositide control.
Ricci MMC, Orenberg A, Ohayon L, Gau D, Wills RC, Bae Y, Das T, Koes D, Hammond GRV, Roy P., Free PMC Article | 02/13/2024 |
| Profilin1 is required for prevention of mitotic catastrophe in murine and human glomerular diseases. | Profilin1 is required for prevention of mitotic catastrophe in murine and human glomerular diseases.
Tian X, Pedigo CE, Li K, Ma X, Bunda P, Pell J, Lek A, Gu J, Zhang Y, Medina Rangel PX, Li W, Schwartze E, Nagata S, Lerner G, Perincheri S, Priyadarshini A, Zhao H, Lek M, Menon MC, Fu R, Ishibe S., Free PMC Article | 12/26/2023 |
| Association of PFN1 Gene Polymorphisms with Bone Mineral Density, Bone Turnover Markers, and Osteoporotic Fractures in Chinese Population. | Association of PFN1 Gene Polymorphisms with Bone Mineral Density, Bone Turnover Markers, and Osteoporotic Fractures in Chinese Population.
Wu Y, Wu S, Yang E, Zhang G, Shi Q, Liang J, Lian X, Xu J. | 08/9/2023 |
| Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation. | Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
Chen X, Song QL, Wang JY, Ji R, Li ZH, Cao ML, Mu XF, Guo DY, Zhang Y, Yang J. | 08/1/2023 |
| ALS-causing hPFN1 mutants differentially disrupt LLPS of FUS prion-like domain. | ALS-causing hPFN1 mutants differentially disrupt LLPS of FUS prion-like domain.
Kang J, Lim L, Song J. | 06/12/2023 |
| Profilin 1 deficiency drives mitotic defects and reduces genome stability. | Profilin 1 deficiency drives mitotic defects and reduces genome stability.
Scotto di Carlo F, Russo S, Muyas F, Mangini M, Garribba L, Pazzaglia L, Genesio R, Biamonte F, De Luca AC, Santaguida S, Scotlandi K, Cortés-Ciriano I, Gianfrancesco F., Free PMC Article | 01/28/2023 |
| Trophoblast Exosomal UCA1 Induces Endothelial Injury through the PFN1-RhoA/ROCK Pathway in Preeclampsia: A Human-Specific Adaptive Pathogenic Mechanism. | Trophoblast Exosomal UCA1 Induces Endothelial Injury through the PFN1-RhoA/ROCK Pathway in Preeclampsia: A Human-Specific Adaptive Pathogenic Mechanism.
Wu S, Cui Y, Zhao H, Xiao X, Gong L, Xu H, Zhou Q, Ma D, Li X., Free PMC Article | 10/1/2022 |
| PFN1 Prevents Psoriasis Pathogenesis through IkappaBzeta Regulation. | PFN1 Prevents Psoriasis Pathogenesis through IκBζ Regulation.
Mok BR, Kim AR, Baek SH, Ahn JH, Seok SH, Shin JU, Kim DH. | 08/27/2022 |
| Histidine tautomerism dependent conformational transitions driven aggregation of profilin-1: Implications in amyotrophic lateral sclerosis. | Histidine tautomerism dependent conformational transitions driven aggregation of profilin-1: Implications in amyotrophic lateral sclerosis.
Muneeswaran G, Lee JY. | 07/30/2022 |
| Detection of structural and conformational changes in ALS-causing mutant profilin-1 with hydrogen/deuterium exchange mass spectrometry and bioinformatics techniques. | Detection of structural and conformational changes in ALS-causing mutant profilin-1 with hydrogen/deuterium exchange mass spectrometry and bioinformatics techniques.
Sadr AS, Abdollahpour Z, Aliahmadi A, Eslahchi C, Nekouei M, Kiaei L, Kiaei M, Ghassempour A. | 07/16/2022 |
| Visualizing molecules of functional human profilin. | Visualizing molecules of functional human profilin.
Pimm ML, Liu X, Tuli F, Heritz J, Lojko A, Henty-Ridilla JL., Free PMC Article | 07/9/2022 |
| The Amyotrophic Lateral Sclerosis M114T PFN1 Mutation Deregulates Alternative Autophagy Pathways and Mitochondrial Homeostasis. | The Amyotrophic Lateral Sclerosis M114T PFN1 Mutation Deregulates Alternative Autophagy Pathways and Mitochondrial Homeostasis.
Teyssou E, Chartier L, Roussel D, Perera ND, Nemazanyy I, Langui D, Albert M, Larmonier T, Saker S, Salachas F, Pradat PF, Meininger V, Ravassard P, Côté F, Lobsiger CS, Boillée S, Turner BJ, Seilhean D, Millecamps S., Free PMC Article | 06/11/2022 |
| Decrease in LINC00963 attenuates the progression of pulmonary arterial hypertension via microRNA-328-3p/profilin 1 axis. | Decrease in LINC00963 attenuates the progression of pulmonary arterial hypertension via microRNA-328-3p/profilin 1 axis.
Yang C, Rong R, Li Y, Cheng M, Luo Y., Free PMC Article | 05/21/2022 |
| Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1. | Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1.
Zhu C, Kim SJ, Mooradian A, Wang F, Li Z, Holohan S, Collins PL, Wang K, Guo Z, Hoog J, Ma CX, Oltz EM, Held JM, Shao J., Free PMC Article | 02/5/2022 |
| Serum levels of cytoskeleton remodeling proteins and their mRNA expression in tumor tissue of metastatic laryngeal and hypopharyngeal cancers. | Serum levels of cytoskeleton remodeling proteins and their mRNA expression in tumor tissue of metastatic laryngeal and hypopharyngeal cancers.
Kakurina GV, Cheremisina OV, Sereda EE, Kolegova ES, Kondakova IV, Choinzonov EL. | 01/22/2022 |
| Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation. | Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation.
Zhang S, Guo X, Liu X, Zhong Z, Yang S, Wang H. | 01/1/2022 |
| ALS-linked PFN1 variants exhibit loss and gain of functions in the context of formin-induced actin polymerization. | ALS-linked PFN1 variants exhibit loss and gain of functions in the context of formin-induced actin polymerization.
Schmidt EJ, Funes S, McKeon JE, Morgan BR, Boopathy S, O'Connor LC, Bilsel O, Massi F, Jégou A, Bosco DA., Free PMC Article | 12/11/2021 |
| Prognostic and clinicopathologic value of ki-67 and profilin 1 immunohistochemical expression in primary pT1 urothelial bladder cancer. | Prognostic and clinicopathologic value of ki-67 and profilin 1 immunohistochemical expression in primary pT1 urothelial bladder cancer.
Culpan M, Turan T, Ozkanli SS, Zenginkinet T, Kazan O, Ucar T, Atis G, Caskurlu T, Yildirim A. | 12/11/2021 |
| The actin regulator profilin 1 is functionally associated with the mammalian centrosome. | The actin regulator profilin 1 is functionally associated with the mammalian centrosome.
Nejedlá M, Klebanovych A, Sulimenko V, Sulimenko T, Dráberová E, Dráber P, Karlsson R., Free PMC Article | 09/18/2021 |
| Upregulated Expression of Profilin1 on Dendritic Cells in Patients With Severe Aplastic Anemia. | Upregulated Expression of Profilin1 on Dendritic Cells in Patients With Severe Aplastic Anemia.
Yu H, Zhao Y, Pan X, Liu C, Fu R., Free PMC Article | 09/18/2021 |
| Mutations in Profilin 1 Cause Early-Onset Paget's Disease of Bone With Giant Cell Tumors. | Mutations in Profilin 1 Cause Early-Onset Paget's Disease of Bone With Giant Cell Tumors.
Wei Z, Li S, Tao X, Zhu G, Sun Z, Wei Z, Jiao Q, Zhang H, Chen L, Li B, Zhang Z, Yue H., Free PMC Article | 09/18/2021 |
| The Loss of Profilin 1 Causes Early Onset Paget's Disease of Bone. | The Loss of Profilin 1 Causes Early Onset Paget's Disease of Bone.
Scotto di Carlo F, Pazzaglia L, Esposito T, Gianfrancesco F. | 09/18/2021 |
| Knockdown of CK2alpha reduces P-cresol-induced fibrosis in human renal proximal tubule epithelial cells via the downregulation of profilin-1. | Knockdown of CK2α reduces P-cresol-induced fibrosis in human renal proximal tubule epithelial cells via the downregulation of profilin-1.
Yoon YM, Go G, Yun CW, Lim JH, Lee SH., Free PMC Article | 08/7/2021 |