| Biological Relevance of Dual Lysine and N-Terminal Methyltransferase METTL13. | Biological Relevance of Dual Lysine and N-Terminal Methyltransferase METTL13.
Boulter M, Biggar KK., Free PMC Article | 10/8/2024 |
| METTL13 promotes nasopharyngeal carcinoma progression through regulating the ZEB1/TPT1 axis. | METTL13 promotes nasopharyngeal carcinoma progression through regulating the ZEB1/TPT1 axis.
Ni H, Liang C, Zhou Z, Jiang B, Li Y, Shang H, Yu X. | 05/5/2023 |
| METTL13 inhibits progression of clear cell renal cell carcinoma with repression on PI3K/AKT/mTOR/HIF-1alpha pathway and c-Myc expression. | METTL13 inhibits progression of clear cell renal cell carcinoma with repression on PI3K/AKT/mTOR/HIF-1α pathway and c-Myc expression.
Liu Z, Sun T, Piao C, Zhang Z, Kong C., Free PMC Article | 07/10/2021 |
| MiR-16 inhibits hepatocellular carcinoma progression by targeting FEAT through NF-kappaB signaling pathway. | MiR-16 inhibits hepatocellular carcinoma progression by targeting FEAT through NF-κB signaling pathway.
Su XF, Li N, Meng FL, Chu YL, Li T, Gao XZ. | 11/21/2020 |
| METTL13 and eEF1AK55me2 levels are upregulated in cancer and negatively correlate with pancreatic and lung cancer patient survival. METTL13 deletion and eEF1AK55me2 loss dramatically reduce Ras-driven neoplastic growth in mouse models and in patient-derived xenografts (PDXs) from primary pancreatic and lung tumors. | METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis.
Liu S, Hausmann S, Carlson SM, Fuentes ME, Francis JW, Pillai R, Lofgren SM, Hulea L, Tandoc K, Lu J, Li A, Nguyen ND, Caporicci M, Kim MP, Maitra A, Wang H, Wistuba II, Porco JA Jr, Bassik MC, Elias JE, Song J, Topisirovic I, Van Rechem C, Mazur PK, Gozani O., Free PMC Article | 11/30/2019 |
| The Mettl3-Mettl14-mediated m6A was found to promote the development of acute myeloid leukemia and maintain leukemia-initiating cells. | Mettl3-Mettl14 methyltransferase complex regulates the quiescence of adult hematopoietic stem cells.
Yao QJ, Sang L, Lin M, Yin X, Dong W, Gong Y, Zhou BO., Free PMC Article | 09/28/2019 |
| The DFNM1 gene modified the phenotype of a inherited deafness family possibly by silencing the DFNB26 mutated gene. | Some deafness-causing mutations can be silenced with the appropriate gene partner.
Wilcox E, Riazuddin S, Riazuddin S., Free PMC Article | 09/21/2019 |
| Modifier variant of METTL13 suppresses human GAB1-associated profound deafness. | Modifier variant of METTL13 suppresses human GAB1-associated profound deafness.
Yousaf R, Ahmed ZM, Giese AP, Morell RJ, Lagziel A, Dabdoub A, Wilcox ER, Riazuddin S, Friedman TB, Riazuddin S., Free PMC Article | 09/14/2019 |
| disease-free survival and overall survival were significantly shorter in breast cancer patients with high FEAT expression than in those with low expression of FEAT | FEAT expression correlates with tumor size, PR status, HER2 expression, Ki67 index, and molecular subtype and predicts recurrence in breast cancer.
Wang SM, Ye M, Zhou J, Ni SM, Wei QC. | 04/27/2019 |
| METTL13 gene rs2232825 locus or a linked functional locus may modulate the vulnerability to development of postpartum psychosis. | Estrogen pathway related genes and their association with risk of postpartum psychosis: A case control study.
Thippeswamy H, Paul P, Purushottam M, Philip M, Jain S, Chandra PS. | 09/29/2018 |
| Single nucleotide polymorphism association study demonstrated association METTL13 on chromosome 1 with Postpartum Depression.METTL13 is putatively involved with methyltransferase activity, which has been shown to play a role in estrogen receptor-induced gene transcription. | Reproductive Affective Disorders: a Review of the Genetic Evidence for Premenstrual Dysphoric Disorder and Postpartum Depression.
McEvoy K, Osborne LM, Nanavati J, Payne JL. | 05/12/2018 |