| The induction of SHP-1 degradation by TAOK3 ensures the responsiveness of T cells to TCR stimulation. | The induction of SHP-1 degradation by TAOK3 ensures the responsiveness of T cells to TCR stimulation.
Poirier A, Ormonde JVS, Aubry I, Abidin BM, Feng CH, Martinez-Cordova Z, Hincapie AM, Wu C, Pérez-Quintero LA, Wang CL, Gingras AC, Madrenas J, Tremblay ML. | 01/4/2024 |
| TAOK3 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance Through Augmenting Autophagy Mediated by IRGM. | TAOK3 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance Through Augmenting Autophagy Mediated by IRGM.
Sun M, Li Z, Wang X, Zhao M, Chu Y, Zhang Z, Fang K, Zhao Z, Feng A, Leng Z, Shi J, Zhang L, Chen T, Xu M., Free PMC Article | 10/25/2023 |
| The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice. | The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice.
Maes B, Smole U, Vanderkerken M, Deswarte K, Van Moorleghem J, Vergote K, Vanheerswynghels M, De Wolf C, De Prijck S, Debeuf N, Pavie B, Toussaint W, Janssens S, Savvides S, Lambrecht BN, Hammad H. | 04/23/2022 |
| STE20-type kinase TAOK3 regulates hepatic lipid partitioning. | STE20-type kinase TAOK3 regulates hepatic lipid partitioning.
Xia Y, Caputo M, Cansby E, Anand SK, Sütt S, Henricsson M, Porosk R, Marschall HU, Blüher M, Mahlapuu M., Free PMC Article | 03/26/2022 |
| Kinase shRNA screening reveals that TAOK3 enhances microtubule-targeted drug resistance of breast cancer cells via the NF-kappaB signaling pathway. | Kinase shRNA screening reveals that TAOK3 enhances microtubule-targeted drug resistance of breast cancer cells via the NF-κB signaling pathway.
Lai TC, Fang CY, Jan YH, Hsieh HL, Yang YF, Liu CY, Chang PM, Hsiao M., Free PMC Article | 08/14/2021 |
| Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5alpha Promotes Cancer Invasion and Tumor Growth. | Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5α Promotes Cancer Invasion and Tumor Growth.
Iizuka S, Quintavalle M, Navarro JC, Gribbin KP, Ardecky RJ, Abelman MM, Ma CT, Sergienko E, Zeng FY, Pass I, Thomas GV, McWeeney SK, Hassig CA, Pinkerton AB, Courtneidge SA., Free PMC Article | 06/26/2021 |
| TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization. | TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization.
Li Z, Oh H, Cung M, Marquez SJ, Sun J, Hammad H, Janssens S, Pouliot P, Lambrecht BN, Yang YS, Shim JH, Greenblatt MB., Free PMC Article | 03/20/2021 |
| TAOK3 SNPs (rs1277441 and rs795484) were associated with opioid doses in advanced cancer patients receiving palliative care. The proportions of variant homozygotes (8.2% of patients) and their requirement for higher doses of opioids would appear potentially clinically important and should be validated in further studies. | Single-Nucleotide Polymorphisms in TAOK3 Are Associated With High Opioid Requirement for Pain Management in Patients With Advanced Cancer Admitted to a Tertiary Palliative Care Unit.
Gutteridge T, Kumaran M, Ghosh S, Fainsinger R, Klepstad P, Tarumi Y, Damaraju S, Baracos VE. | 10/26/2019 |
| TAOK3 is a positive regulator of TCR signaling by preventing premature SHP-1-mediated inactivation of LCK | TAOK3 Regulates Canonical TCR Signaling by Preventing Early SHP-1-Mediated Inactivation of LCK.
Ormonde JVS, Li Z, Stegen C, Madrenas J. | 08/10/2019 |
| Results show that three CpG loci within FYN were hypermethylated in obese individuals, while obesity was associated with lower methylation of CpG loci within PIWIL4 and TAOK3. | Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood.
Huang RC, Garratt ES, Pan H, Wu Y, Davis EA, Barton SJ, Burdge GC, Godfrey KM, Holbrook JD, Lillycrop KA., Free PMC Article | 10/22/2016 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |