PLCε promotes the Warburg effect and tumorigenesis through AKT/GSK3β/Cdc25a in bladder cancer.
Fan Y, Hao Y, Zhu C, Hu B, Ma R, Liu Y, Li G.

Phospholipase C epsilon-1 (PLCƐ1) mediates macrophage activation and protection against tuberculosis.
Gupta A, Thirunavukkarasu S, Rangel-Moreno J, Ahmed M, Swanson RV, Mbandi SK, Smrcka AV, Kaushal D, Scriba TJ, Khader SA., Free PMC Article

Copy number variation analysis in 138 families with steroid-resistant nephrotic syndrome identifies causal homozygous deletions in PLCE1 and NPHS2 in two families.
Pantel D, Mertens ND, Schneider R, Hölzel S, Kari JA, Desoky SE, Shalaby MA, Lim TY, Sanna-Cherchi S, Shril S, Hildebrandt F., Free PMC Article

Association between the Missense Variant of PLCE1 and the Risk of Colorectal Cancer.
Gao XR, Pan JJ, Nie WJ, Li XY, Zhang SL.

Phospholipase Cε insufficiency causes ascending aortic aneurysm and dissection.
Atchison DK, O'Connor CL, Converso-Baran K, Bergin IL, Zhang H, Wang Y, Hartman JR, Ju W, Smrcka AV, Ganesh SK, Bitzer M., Free PMC Article

[Association of GSTP1 and PLCE1 gene polymorphisms with primary esophageal cancer].
Han W, Li W, He Z.

PLCE1 is a poor prognostic marker and may promote immune escape from osteosarcoma by the CD70-CD27 signaling pathway.
Huang L, Liao C, Wu H, Huang P., Free PMC Article

PLCE1 as a diagnostic and prognostic biomarker by promoting the growth and progression of oral squamous cell carcinoma.
Abulaiti Z, Chen L, Xiao Q, Aimaier A, Ma Y, He S, Zhang J, Xu J, Cui X.

A broad clinical spectrum of PLCε1-related kidney disease and intrafamilial variability.
Yılmaz EK, Saygili S, Gulhan B, Canpolat N, Bayazıt AK, Kilic BD, Akıncı N, Benzer M, Goknar N, Tufan AK, Kalyoncu M, Nalcacioglu H, Tekcan D, Yıldız G, Agbas A, Nayır A, Topaloglu R, Caliskan S, Ozaltin F.

The Frequency of Genetic Mutations in Pediatric Patients Diagnosed with Nephrotic Syndrome: A Single-Center Retrospective Study in Saudi Arabia.
Almokali K, Alyami A, Ajeebi A, Almutairi T, Aldriwesh M.

CircPLCE1 facilitates the malignant progression of colorectal cancer by repressing the SRSF2-dependent PLCE1 pre-RNA splicing.
Chen Z, Chen H, Yang L, Li X, Wang Z., Free PMC Article

A novel NF-κB regulator encoded by circPLCE1 inhibits colorectal carcinoma progression by promoting RPS3 ubiquitin-dependent degradation.
Liang ZX, Liu HS, Xiong L, Yang X, Wang FW, Zeng ZW, He XW, Wu XR, Lan P., Free PMC Article

MicroRNA-199b-3p suppresses malignant proliferation by targeting Phospholipase Cε and correlated with poor prognosis in prostate cancer.
Liu J, Quan Z, Gao Y, Wu X, Zheng Y.

Independent and opposing associations of dietary phytosterols intake and PLCE1 rs2274223 polymorphisms on esophageal squamous cell carcinoma risk.
Wang S, Zhao W, Sun L, Xiao SM, Lin S, Zhao J, Xiao H, Xing X, Lao XQ, Chen YM, Liu X.

Maternal Hypertension-Related Genotypes and Congenital Heart Defects.
Lei Y, Ludorf KL, Yu X, Benjamin RH, Gu X, Lin Y, Finnell RH, Mitchell LE, Musfee FI, Malik S, Canfield MA, Morrison AC, Hobbs CA, Van Zutphen AR, Fisher S, Agopian AJ., Free PMC Article

Identification of a PLCE1‑regulated competing endogenous RNA regulatory network for esophageal squamous cell carcinoma.
Yang Z, Hui Y, Peng H, Zhang H, Li M, Song L, Li F, Cui X., Free PMC Article

The PLCE1 rs2274223 variant is associated with the risk of laryngeal squamous cell carcinoma.
Zhang Y, Li W, Wang Y, Wang N., Free PMC Article

PLCE1 regulates the migration, proliferation, and differentiation of podocytes.
Yu S, Choi WI, Choi YJ, Kim HY, Hildebrandt F, Gee HY., Free PMC Article

Genetic variants in GHR and PLCE1 genes are associated with susceptibility to esophageal cancer.
Wang R, Si L, Zhu D, Shen G, Long Q, Zhao Y., Free PMC Article

Functional and structural characterization of allosteric activation of phospholipase Cε by Rap1A.
Sieng M, Selvia AF, Garland-Kuntz EE, Hopkins JB, Fisher IJ, Marti AT, Lyon AM., Free PMC Article

An Association and Meta-Analysis of Esophageal Squamous Cell Carcinoma Risk Associated with PLCE1 rs2274223, C20orf54 rs13042395 and RUNX1 rs2014300 Polymorphisms.
Nariman-Saleh-Fam Z, Saadatian Z, Nariman-Saleh-Fam L, Ouladsahebmadarek E, Tavakkoly-Bazzaz J, Bastami M.

PLCε regulates metabolism and metastasis signaling via HIF-1α/MEK/ERK pathway in prostate cancer.
Fan Y, Ou L, Fan J, Li L, Wang X, Niu L, Wu X, Luo C.

Oncogene PLCE1 may be a diagnostic biomarker and prognostic biomarker by influencing cell cycle, proliferation, migration, and invasion ability in hepatocellular carcinoma cell lines.
Wang XK, Liao XW, Yang CK, Liu ZQ, Han QF, Zhou X, Zhang LB, Deng T, Gong YZ, Huang JL, Huang R, Han CY, Yu TD, Su H, Ye XP, Peng T, Zhu GZ.

Hypomethylation-Linked Activation of PLCE1 Impedes Autophagy and Promotes Tumorigenesis through MDM2-Mediated Ubiquitination and Destabilization of p53.
Chen Y, Xin H, Peng H, Shi Q, Li M, Yu J, Tian Y, Han X, Chen X, Zheng Y, Li J, Yang Z, Yang L, Hu J, Huang X, Liu Z, Huang X, Zhou H, Cui X, Li F.

Phospholipase C-related catalytically inactive protein regulates cytokinesis by protecting phosphatidylinositol 4,5-bisphosphate from metabolism in the cleavage furrow.
Asano S, Ikura Y, Nishimoto M, Yamawaki Y, Hamao K, Kamijo K, Hirata M, Kanematsu T., Free PMC Article