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    PBX1 PBX homeobox 1 [ Homo sapiens (human) ]

    Gene ID: 5087, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Whole Exome Sequencing Revealing a Novel PBX1 Gene Variant in a Chinese Family Causing Recurrent Neonatal Death.

    Whole Exome Sequencing Revealing a Novel PBX1 Gene Variant in a Chinese Family Causing Recurrent Neonatal Death.
    Huang N, Zhang H, Huang Z, Wu X, Zhang N, Jiang Y, Chen C, Zhuang J.

    10/1/2024
    PBX1 as a novel master regulator in cancer: Its regulation, molecular biology, and therapeutic applications.

    PBX1 as a novel master regulator in cancer: Its regulation, molecular biology, and therapeutic applications.
    Kao TW, Chen HH, Lin J, Wang TL, Shen YA.

    04/12/2024
    Lupus susceptibility gene Pbx1 controls the development, stability, and function of regulatory T cells via Rtkn2 expression.

    Lupus susceptibility gene Pbx1 controls the development, stability, and function of regulatory T cells via Rtkn2 expression.
    Choi SC, Park YP, Roach T, Jimenez D, Fisher A, Zadeh M, Ma L, Sobel ES, Ge Y, Mohamadzadeh M, Morel L., Free PMC Article

    04/3/2024
    Exosomal lncRNA NEAT1 Inhibits NK-Cell Activity to Promote Multiple Myeloma Cell Immune Escape via an EZH2/PBX1 Axis.

    Exosomal lncRNA NEAT1 Inhibits NK-Cell Activity to Promote Multiple Myeloma Cell Immune Escape via an EZH2/PBX1 Axis.
    Wang QM, Lian GY, Sheng SM, Xu J, Ye LL, Min C, Guo SF.

    02/7/2024
    Regulation of the STAT3 pathway by lupus susceptibility gene Pbx1 in T cells.

    Regulation of the STAT3 pathway by lupus susceptibility gene Pbx1 in T cells.
    Roach T, Park YP, Choi SC, Morel L.

    02/1/2024
    Small nucleolar RNA Snora73 promotes psoriasis progression by sponging miR-3074-5p and regulating PBX1 expression.

    Small nucleolar RNA Snora73 promotes psoriasis progression by sponging miR-3074-5p and regulating PBX1 expression.
    Zhang L, Guo H, Zhang X, Wang L, Wei F, Zhao Y, Wang B, Meng Y, Li Y., Free PMC Article

    02/1/2024
    Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging.

    Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging.
    Wen Y, Chen H, Wang Y, Sun Y, Dou F, Du X, Liu T, Chen C., Free PMC Article

    01/8/2024
    Mesenchymal stem cells overexpressing PBX1 alleviates haemorrhagic shock-induced kidney damage by inhibiting NF-kappaB activation.

    Mesenchymal stem cells overexpressing PBX1 alleviates haemorrhagic shock-induced kidney damage by inhibiting NF-κB activation.
    Jia D, Han J, Cai J, Huan Z, Wang Y, Ge X.

    12/15/2023
    Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment.

    Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment.
    Burmeister T, Gröger D, Gökbuget N, Spriewald B, Starck M, Elmaagacli A, Hoelzer D, Keller U, Schwartz S., Free PMC Article

    09/19/2023
    PBX1-promoted SFRP4 transcription inhibits cell proliferation and epithelial-mesenchymal transition in endometrial carcinoma.

    PBX1-promoted SFRP4 transcription inhibits cell proliferation and epithelial-mesenchymal transition in endometrial carcinoma.
    Guo L, Chen H, Chen J, Gao C, Fu X, Zhou S, Wu W, Li T, Lin J, Yang T, Chen Z, Cao L.

    06/23/2023
    PBX1 attenuates H2O2-induced oxidant stress in human trabecular meshwork cells via promoting NANOG-mediated PI3K/AKT signaling pathway.

    PBX1 attenuates H(2)O(2)-induced oxidant stress in human trabecular meshwork cells via promoting NANOG-mediated PI3K/AKT signaling pathway.
    Wang L, Tian Y, Cao Y, Ma Q, Zhao S., Free PMC Article

    11/26/2022
    Targeting SPHK1/PBX1 Axis Induced Cell Cycle Arrest in Non-Small Cell Lung Cancer.

    Targeting SPHK1/PBX1 Axis Induced Cell Cycle Arrest in Non-Small Cell Lung Cancer.
    Lin Z, Li Y, Han X, Fu Z, Tian Z, Li C., Free PMC Article

    11/19/2022
    Genetic features of B-cell lymphoblastic lymphoma with TCF3-PBX1.

    Genetic features of B-cell lymphoblastic lymphoma with TCF3-PBX1.
    Shirai R, Osumi T, Sato-Otsubo A, Nakabayashi K, Mori T, Yoshida M, Yoshida K, Kohri M, Ishihara T, Yasue S, Imamura T, Endo M, Miyamoto S, Ohki K, Sanada M, Kiyokawa N, Ogawa S, Yoshioka T, Hata K, Takagi M, Kato M., Free PMC Article

    09/24/2022
    PBX1 Participates in Estrogen-mediated Bladder Cancer Progression and Chemo-resistance Affecting Estrogen Receptors.

    PBX1 Participates in Estrogen-mediated Bladder Cancer Progression and Chemo-resistance Affecting Estrogen Receptors.
    Zhao Y, Che J, Tian A, Zhang G, Xu Y, Li S, Liu S, Wan Y.

    09/17/2022
    The TALE never ends: A comprehensive overview of the role of PBX1, a TALE transcription factor, in human developmental defects.

    The TALE never ends: A comprehensive overview of the role of PBX1, a TALE transcription factor, in human developmental defects.
    Mary L, Leclerc D, Gilot D, Belaud-Rotureau MA, Jaillard S.

    08/13/2022
    PBX1: a key character of the hallmarks of cancer.

    PBX1: a key character of the hallmarks of cancer.
    Veiga RN, de Oliveira JC, Gradia DF.

    02/26/2022
    Genome-Wide Association Study of Susceptibility Loci for TCF3-PBX1 Acute Lymphoblastic Leukemia in Children.

    Genome-Wide Association Study of Susceptibility Loci for TCF3-PBX1 Acute Lymphoblastic Leukemia in Children.
    Lee SHR, Qian M, Yang W, Diedrich JD, Raetz E, Yang W, Dong Q, Devidas M, Pei D, Yeoh A, Cheng C, Pui CH, Evans WE, Mullighan CG, Hunger SP, Savic D, Relling MV, Loh ML, Yang JJ., Free PMC Article

    02/26/2022
    rs6426881 in the 3'-UTR of PBX1 is involved in breast and gastric cancers via altering the binding potential of miR-522-3p.

    rs6426881 in the 3'-UTR of PBX1 is involved in breast and gastric cancers via altering the binding potential of miR-522-3p.
    Mohammadi M, Salehzadeh A, Talesh Sasani S, Tarang A.

    01/15/2022
    The clinical outcomes and genomic landscapes of acute lymphoblastic leukemia patients with E2A-PBX1: A 10-year retrospective study.

    The clinical outcomes and genomic landscapes of acute lymphoblastic leukemia patients with E2A-PBX1: A 10-year retrospective study.
    Zhou B, Chu X, Tian H, Liu T, Liu H, Gao W, Chen S, Hu S, Wu D, Xu Y.

    11/22/2021
    Coexpression of PBX1 and EMP2 as Prognostic Biomarkers in Estrogen Receptor-Negative Breast Cancer via Data Mining.

    Coexpression of PBX1 and EMP2 as Prognostic Biomarkers in Estrogen Receptor-Negative Breast Cancer via Data Mining.
    Qiu Y, Lu G, Wu Y.

    09/25/2021
    Upregulation of microRNA-650 by PBX1 is correlated with the development of Helicobacter pylori-associated gastric carcinoma.

    Upregulation of microRNA-650 by PBX1 is correlated with the development of Helicobacter pylori-associated gastric carcinoma.
    Liu J, Wang L, Li J, Xu Y.

    08/21/2021
    Establishment of the TALE-code reveals aberrantly activated homeobox gene PBX1 in Hodgkin lymphoma.

    Establishment of the TALE-code reveals aberrantly activated homeobox gene PBX1 in Hodgkin lymphoma.
    Nagel S, Pommerenke C, Meyer C, MacLeod RAF, Drexler HG., Free PMC Article

    08/14/2021
    Functional characterization of a novel PBX1 de novo missense variant identified in a patient with syndromic congenital heart disease.

    Functional characterization of a novel PBX1 de novo missense variant identified in a patient with syndromic congenital heart disease.
    Alankarage D, Szot JO, Pachter N, Slavotinek A, Selleri L, Shieh JT, Winlaw D, Giannoulatou E, Chapman G, Dunwoodie SL., Free PMC Article

    08/7/2021
    PBX1 Increases the Radiosensitivity of Oesophageal Squamous Cancer by Targeting of STAT3.

    PBX1 Increases the Radiosensitivity of Oesophageal Squamous Cancer by Targeting of STAT3.
    Yu D, Ma Y, Feng C, Ma Z, Guo J, Chen H, He T, Guo J, Sun X, Qin Q, Sun X, Ma J.

    07/17/2021
    Inherited intragenic PBX1 deletion: Expanding the phenotype.

    Inherited intragenic PBX1 deletion: Expanding the phenotype.
    Fitzgerald KK, Powell-Hamilton N, Shillingford AJ, Robinson B, Gripp KW.

    07/3/2021
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