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    ODF2 outer dense fiber of sperm tails 2 [ Homo sapiens (human) ]

    Gene ID: 4957, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Sperm DNA fragmentation and apoptosis in the sperm of men with oligozoospermia are closely related to anti-ODF2 autoantibodies.

    Sperm DNA fragmentation and apoptosis in the sperm of men with oligozoospermia are closely related to anti-ODF2 autoantibodies.
    Kiani A, Döğüş Y, Saadatnia S, Yazdani Y, Asadi F, Al-Naqeeb BZT, Masouleh SS, Merza MS, Daemi A, Rahimi A.

    05/20/2023
    Pericentriolar matrix (PCM) integrity relies on cenexin and polo-like kinase (PLK)1.

    Pericentriolar matrix (PCM) integrity relies on cenexin and polo-like kinase (PLK)1.
    Aljiboury A, Mujcic A, Curtis E, Cammerino T, Magny D, Lan Y, Bates M, Freshour J, Ahmed-Braimeh YH, Hehnly H., Free PMC Article

    07/30/2022
    alpha-/gamma-Taxilin are required for centriolar subdistal appendage assembly and microtubule organization.

    α-/γ-Taxilin are required for centriolar subdistal appendage assembly and microtubule organization.
    Ma D, Wang F, Wang R, Hu Y, Chen Z, Huang N, Tian Y, Xia Y, Teng J, Chen J., Free PMC Article

    03/5/2022
    MicroRNA-targeting in spermatogenesis: Over-expressions of microRNA-23a/b-3p and its affected targeting of the genes ODF2 and UBQLN3 in spermatozoa of patients with oligoasthenozoospermia.

    MicroRNA-targeting in spermatogenesis: Over-expressions of microRNA-23a/b-3p and its affected targeting of the genes ODF2 and UBQLN3 in spermatozoa of patients with oligoasthenozoospermia.
    Abu-Halima M, Belkacemi A, Ayesh BM, Simone Becker L, Sindiani AM, Fischer U, Hammadeh M, Keller A, Meese E.

    01/15/2022
    C3G localizes to the mother centriole in a cenexin-dependent manner and regulates centrosome duplication and primary cilium length.

    C3G localizes to the mother centriole in a cenexin-dependent manner and regulates centrosome duplication and primary cilium length.
    Nayak SC, Radha V.

    07/31/2021
    Odf2 interacts with Cep128 to form the subdistal appendage of the centriole.

    Cep128 associates with Odf2 to form the subdistal appendage of the centriole.
    Kashihara H, Chiba S, Kanno SI, Suzuki K, Yano T, Tsukita S.

    04/20/2019
    Cenexin controls centrosome positioning during cell migration by modulating microtubule organization and stability.Cenexin is required for spindle orientation.

    The Mother Centriole Appendage Protein Cenexin Modulates Lumen Formation through Spindle Orientation.
    Hung HF, Hehnly H, Doxsey S., Free PMC Article

    12/17/2016
    Cby plays an important role in organization of both primary and motile cilia in collaboration with Cnx.

    A Wnt/beta-catenin pathway antagonist Chibby binds Cenexin at the distal end of mother centrioles and functions in primary cilia formation.
    Steere N, Chae V, Burke M, Li FQ, Takemaru K, Kuriyama R., Free PMC Article

    04/20/2013
    Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.

    Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.
    Ibi M, Zou P, Inoko A, Shiromizu T, Matsuyama M, Hayashi Y, Enomoto M, Mori D, Hirotsune S, Kiyono T, Tsukita S, Goto H, Inagaki M.

    06/18/2011
    Cdk5 in the centriolar appendages mediates cenexin1 localization and primary cilia formation.

    Cdk5 in the centriolar appendages mediates cenexin1 localization and primary cilia formation.
    Rosales JL, Rattner JB, Lee KY.

    05/7/2011
    Mouse and rat ODF2 protein homolog sequences and expression are compared.

    Mouse Odf2 cDNAs consist of evolutionary conserved as well as highly variable sequences and encode outer dense fiber proteins of the sperm tail.
    Hoyer-Fender S, Petersen C, Brohmann H, Rhee K, Wolgemuth DJ.

    10/25/2010
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    A splice variant of hODF2 called hCenexin1, but not hODF2 itself, efficiently localizes to somatic centrosomes via a variant-specific C-terminal extension and recruits Plk1 through a Cdc2-dependent phospho-S796 motif within the extension.

    Plk1-dependent and -independent roles of an ODF2 splice variant, hCenexin1, at the centrosome of somatic cells.
    Soung NK, Park JE, Yu LR, Lee KH, Lee JM, Bang JK, Veenstra TD, Rhee K, Lee KS., Free PMC Article

    01/21/2010
    We propose that hCenexin1 is a critical centrosomal component whose C-terminal extension is required for proper recruitment of Plk1 and other components crucial for normal mitosis.

    Requirement of hCenexin for proper mitotic functions of polo-like kinase 1 at the centrosomes.
    Soung NK, Kang YH, Kim K, Kamijo K, Yoon H, Seong YS, Kuo YL, Miki T, Kim SR, Kuriyama R, Giam CZ, Ahn CH, Lee KS., Free PMC Article

    01/21/2010
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