NNMT switches the proangiogenic phenotype of cancer-associated fibroblasts via epigenetically regulating ETS2/VEGFA axis.
Wang X, Zhao H, Luo X, Chen Y, Shi C, Wang Y, Bai J, Shao Z, Shang Z.

Nicotinamide N-Methyltransferase (NNMT) is Involved in Gastric Adenocarcinoma Immune Infiltration by Driving Amino Acid Metabolism.
Lu J, Gui W, Tang S, Shi Q, Wang X, Huang L, Shen Y, Yang S, Xiang J, Yuan J, Mo J, Kong X, Huang M, Li X, Lu C.

NNMT/1-MNA Promote Cell-Cycle Progression of Breast Cancer by Targeting UBC12/Cullin-1-Mediated Degradation of P27 Proteins.
Ma Y, Huang X, Wang Y, Lei Y, Yu J, Yu S, Gao Y, Yang J, Zhao F, Yu H, Zeng J, Chu Y, Yang M, Li G, Xie X, Zhang J., Free PMC Article

NNMT enriches for AQP5(+) cancer stem cells to drive malignant progression in early gastric cardia adenocarcinoma.
Wang Z, Wang Q, Chen C, Zhao X, Wang H, Xu L, Fu Y, Huang G, Li M, Xu J, Zhang Q, Wang B, Xu G, Wang L, Zou X, Wang S.

Lipid reprogramming induced by the NNMT-ABCA1 axis enhanced membrane fluidity to promote endometrial cancer progression.
Wen Q, Xie X, Chen C, Wen B, Liu Y, Zhou J, Lin X, Jin H, Shi K., Free PMC Article

Nicotinamide N -methyltransferase promotes M2 macrophage polarization by IL6 and MDSC conversion by GM-CSF in gallbladder carcinoma.
Li Y, Yang B, Miao H, Liu L, Wang Z, Jiang C, Yang Y, Qiu S, Li X, Geng Y, Zhang Y, Liu Y.

Proteomics Profiling of Bladder Cancer Tissues from Early to Advanced Stages Reveals NNMT and GALK1 as Biomarkers for Early Detection and Prognosis of BCa.
Davalieva K, Kiprijanovska S, Ivanovski O, Trifunovski A, Saidi S, Dimovski A, Popov Z., Free PMC Article

Nicotinamide N-methyltransferase mediates lipofibroblast-myofibroblast transition and apoptosis resistance.
Rehan M, Deskin B, Kurundkar AR, Yadav S, Matsunaga Y, Manges J, Smith N, Dsouza KG, Burow ME, Thannickal VJ., Free PMC Article

Stromal nicotinamide N-methyltransferase orchestrates the crosstalk between fibroblasts and tumour cells in oral squamous cell carcinoma: evidence from patient-derived assembled organoids.
Zhao H, Li R, Chen Y, Yang X, Shang Z.

NNMT Is an Immune-Related Prognostic Biomarker That Modulates the Tumor Microenvironment in Pan-Cancer.
Liu W, Zhu M, Li X, Er L, Li S., Free PMC Article

Identification of Biological Functions and Prognostic Value of NNMT in Oral Squamous Cell Carcinoma.
Zhang W, Jing Y, Wang S, Wu Y, Sun Y, Zhuang J, Huang X, Chen S, Zhang X, Song Y, Hu Q, Ni Y., Free PMC Article

NNMT contributes to high metastasis of triple negative breast cancer by enhancing PP2A/MEK/ERK/c-Jun/ABCA1 pathway mediated membrane fluidity.
Wang Y, Zhou X, Lei Y, Chu Y, Yu X, Tong Q, Zhu T, Yu H, Fang S, Li G, Wang L, Wang GY, Xie X, Zhang J.

Nicotinamide N-methyltransferase gene silencing enhances chemosensitivity of melanoma cell lines.
Campagna R, Salvolini E, Pompei V, Pozzi V, Salvucci A, Molinelli E, Brisigotti V, Sartini D, Campanati A, Offidani A, Emanuelli M.

Tumor stromal nicotinamide N-methyltransferase overexpression as a prognostic biomarker for poor clinical outcome in early-stage colorectal cancer.
Ogawa M, Tanaka A, Namba K, Shia J, Wang JY, Roehrl MHA., Free PMC Article

Knockdown of long non-coding RNA HOTAIR promotes bone marrow mesenchymal stem cell differentiation by sponging microRNA miR-378g that inhibits nicotinamide N-methyltransferase.
Wang W, Li T, Feng S., Free PMC Article

Nicotinamide N-Methyltransferase: An Emerging Protagonist in Cancer Macro(r)evolution.
Parsons RB, Facey PD., Free PMC Article

Alterations in Kynurenine and NAD(+) Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets.
Wnorowski A, Wnorowska S, Kurzepa J, Parada-Turska J., Free PMC Article

Long non-coding RNA XIST promotes osteoporosis by inhibiting the differentiation of bone marrow mesenchymal stem cell by sponging miR-29b-3p that suppresses nicotinamide N-methyltransferase.
Yu J, Xiao M, Ren G., Free PMC Article

Nicotinamide N-methyltransferase in endothelium protects against oxidant stress-induced endothelial injury.
Campagna R, Mateuszuk Ł, Wojnar-Lason K, Kaczara P, Tworzydło A, Kij A, Bujok R, Mlynarski J, Wang Y, Sartini D, Emanuelli M, Chlopicki S.

Exosomal NNMT from peritoneum lavage fluid promotes peritoneal metastasis in gastric cancer.
Zhu AK, Shan YQ, Zhang J, Liu XC, Ying RC, Kong WC.

Cancer stem cell enrichment is associated with enhancement of nicotinamide N-methyltransferase expression.
Pozzi V, Salvolini E, Lucarini G, Salvucci A, Campagna R, Rubini C, Sartini D, Emanuelli M.

High Expression of Nicotinamide N-Methyltransferase in Patients with Sporadic Alzheimer's Disease.
Kocinaj A, Chaudhury T, Uddin MS, Junaid RR, Ramsden DB, Hondhamuni G, Klamt F, Parsons L, Parsons RB., Free PMC Article

Nicotinamide N-methyltransferase overexpression may be associated with poor prognosis in ovarian cancer.
Harmankaya İ, Akar S, Uğraş S, Güler AH, Ezveci H, Aydoğdu M, Çelik Ç.

Accumulation of Nicotinamide N-Methyltransferase (NNMT) in Cancer-associated Fibroblasts: A Potential Prognostic and Predictive Biomarker for Gastric Carcinoma.
Zhang L, Song M, Zhang F, Yuan H, Chang W, Yu G, Niu Y., Free PMC Article

Patients with low nicotinamide N-methyltransferase expression benefit significantly from bevacizumab treatment in ovarian cancer.
Li J, Yue H, Yu H, Lu X, Xue X., Free PMC Article