| Circular RNA NFIX Functions as an Oncogene in Non-Small Cell Lung Cancer by Modulating the miR-214-3p/TRIAP1 Axis. | Circular RNA NFIX Functions as an Oncogene in Non-Small Cell Lung Cancer by Modulating the miR-214-3p/TRIAP1 Axis.
Liu G, Shi H, Zheng H, Kong W, Cheng X, Deng L., Free PMC Article | 09/23/2024 |
| [NFIX gene mutation causes Marshall-Smith syndrome in a pair of identical twins and literature review]. | [NFIX gene mutation causes Marshall-Smith syndrome in a pair of identical twins and literature review].
Lin XQ, Quan YL, He HL, Peng J., Free PMC Article | 08/15/2024 |
| m6A-modified circNFIX promotes ovarian cancer progression and immune escape via activating IL-6R/JAK1/STAT3 signaling by sponging miR-647. | m6A-modified circNFIX promotes ovarian cancer progression and immune escape via activating IL-6R/JAK1/STAT3 signaling by sponging miR-647.
Wang R, Ye H, Yang B, Ao M, Yu X, Wu Y, Xi M, Hou M. | 11/7/2023 |
| A rare cause of intellectual disability: Novel mutations of NFIX gene in two patients with clinical features of Marshall-Smith syndrome and Malan syndrome. | A rare cause of intellectual disability: Novel mutations of NFIX gene in two patients with clinical features of Marshall-Smith syndrome and Malan syndrome.
Uzman CY, Gürsoy S, Hazan F. | 10/20/2023 |
| NFIXing Cancer: The Role of NFIX in Oxidative Stress Response and Cell Fate. | NFIXing Cancer: The Role of NFIX in Oxidative Stress Response and Cell Fate.
Ribeiro V, Martins SG, Lopes AS, Thorsteinsdóttir S, Zilhão R, Carlos AR., Free PMC Article | 03/17/2023 |
| CircNFIX stimulates the proliferation, invasion, and stemness properties of ovarian cancer cells by enhancing SH3RF3 mRNA stability via binding LIN28B. | CircNFIX stimulates the proliferation, invasion, and stemness properties of ovarian cancer cells by enhancing SH3RF3 mRNA stability via binding LIN28B.
Yu XZ, Yang BW, Ao MY, Wu YK, Ye H, Wang RY, Xi MR, Hou MM. | 03/16/2023 |
| A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1. | A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
Ge R, Wang C, Liu J, Jiang H, Jiang X, Liu Z. | 03/6/2023 |
| CircNFIX regulates chondrogenesis and cartilage homeostasis by targeting the miR758-3p/KDM6A axis. | CircNFIX regulates chondrogenesis and cartilage homeostasis by targeting the miR758-3p/KDM6A axis.
Liao H, Tu Q, Kang Y, Mao G, Li Z, Hu S, Sheng P, Wang X, Xu Y, Long D, Xu Y, Kang Y, Zhang Z., Free PMC Article | 11/12/2022 |
| A novel miRNA-762/NFIX pathway modulates LPS-induced acute lung injury. | A novel miRNA-762/NFIX pathway modulates LPS-induced acute lung injury.
Zhang XL, An J, Deng YZ, Fang XZ, Xu CY, Liu XF, Bai ZH, Zhang G, Cui MY. | 02/12/2022 |
| Pathogenic variant in NFIX gene affecting three sisters due to paternal mosaicism. | Pathogenic variant in NFIX gene affecting three sisters due to paternal mosaicism.
Sihombing NRB, Winarni TI, van Bokhoven H, van der Burgt I, de Leeuw N, Faradz SMH. | 06/26/2021 |
| Excess of de novo variants in genes involved in chromatin remodelling in patients with marfanoid habitus and intellectual disability. | Excess of de novo variants in genes involved in chromatin remodelling in patients with marfanoid habitus and intellectual disability.
Chevarin M, Duffourd Y, A Barnard R, Moutton S, Lecoquierre F, Daoud F, Kuentz P, Cabret C, Thevenon J, Gautier E, Callier P, St-Onge J, Jouan T, Lacombe D, Delrue MA, Goizet C, Morice-Picard F, Van-Gils J, Munnich A, Lyonnet S, Cormier-Daire V, Baujat G, Holder M, Petit F, Leheup B, Odent S, Jouk PS, Lopez G, Geneviève D, Collignon P, Martin-Coignard D, Jacquette A, Perrin L, Putoux A, Sarrazin E, Amarof K, Missotte I, Coubes C, Jagadeesh S, Lapi E, Demurger F, Goldenberg A, Doco-Fenzy M, Mignot C, Héron D, Jean-Marçais N, Masurel A, El Chehadeh S, Marle N, Huet F, Binquet C, Collod-Beroud G, Arnaud P, Hanna N, Boileau C, Jondeau G, Olaso R, Lechner D, Poe C, Assoum M, Carmignac V, Duplomb L, Tran Mau-Them F, Philippe C, Vitobello A, Bruel AL, Boland A, Deleuze JF, Thauvin-Robinet C, Rivière JB, O'Roak BJ, Faivre L. | 06/26/2021 |
| A de-novo NFIX mutation causes a case of neonatal lethal Marshall-Smith syndrome. | A de-novo NFIX mutation causes a case of neonatal lethal Marshall-Smith syndrome.
Bupp C, Junewick J, Hess JL. | 06/19/2021 |
| Malan syndrome due to shared NFIX variants was diagnosed in the brothers using exome sequencing. | Parental gonadal but not somatic mosaicism leading to de novo NFIX variants shared by two brothers with Malan syndrome.
Hancarova M, Havlovicova M, Putzova M, Vseticka J, Prchalova D, Stranecky V, Sedlacek Z. | 08/12/2020 |
| Knockdown of circNFIX inhibits progression of glioma in vitro and in vivo by increasing miR-378e and decreasing RPN2, providing a novel mechanism for understanding the pathogenesis of glioma. | CircNFIX promotes progression of glioma through regulating miR-378e/RPN2 axis.
Ding C, Wu Z, You H, Ge H, Zheng S, Lin Y, Wu X, Lin Z, Kang D., Free PMC Article | 05/16/2020 |
| Secretory carcinoma of the skin associated with the presence of novel NFIX-PKN1 translocation. | Secretory Carcinoma of the Skin: Report of 6 Cases, Including a Case With a Novel NFIX-PKN1 Translocation.
Kastnerova L, Luzar B, Goto K, Grishakov V, Gatalica Z, Kamarachev J, Martinek P, Hájková V, Grossmann P, Imai H, Fukui H, Michal M, Kazakov DV. | 03/28/2020 |
| Data show that miR-744-5p expression directly downregulated mRNA and protein expression of nuclear factor I X (NFIX) and heterogeneous nuclear ribonucleoprotein C (HNRNPC). | MiR-744-5p inducing cell death by directly targeting HNRNPC and NFIX in ovarian cancer cells.
Kleemann M, Schneider H, Unger K, Sander P, Schneider EM, Fischer-Posovszky P, Handrick R, Otte K., Free PMC Article | 10/26/2019 |
| NFIX downregulation might independently predict poor prognosis in LUAD. DNA hypermethylation might be an important cause of the downregulation | NFIX downregulation independently predicts poor prognosis in lung adenocarcinoma, but not in squamous cell carcinoma.
Ge J, Dong H, Yang Y, Liu B, Zheng M, Cheng Q, Peng L, Li J. | 08/10/2019 |
| Malan syndrome is caused by deletions or point mutations of NFIX clustered mostly in exon 2. There is no genotype-phenotype correlation except for an increased risk for epilepsy with 19p13.2 microdeletions. Variants arose de novo, except in one family in which mother was mosaic. Variants causing Malan and Marshall-Smith syndrome can be discerned by differences in the site of stop codon formation | Further delineation of Malan syndrome.
Priolo M, Schanze D, Tatton-Brown K, Mulder PA, Tenorio J, Kooblall K, Acero IH, Alkuraya FS, Arias P, Bernardini L, Bijlsma EK, Cole T, Coubes C, Dapia I, Davies S, Di Donato N, Elcioglu NH, Fahrner JA, Foster A, González NG, Huber I, Iascone M, Kaiser AS, Kamath A, Liebelt J, Lynch SA, Maas SM, Mammì C, Mathijssen IB, McKee S, Menke LA, Mirzaa GM, Montgomery T, Neubauer D, Neumann TE, Pintomalli L, Pisanti MA, Plomp AS, Price S, Salter C, Santos-Simarro F, Sarda P, Segovia M, Shaw-Smith C, Smithson S, Suri M, Valdez RM, Van Haeringen A, Van Hagen JM, Zollino M, Lapunzina P, Thakker RV, Zenker M, Hennekam RC., Free PMC Article | 07/27/2019 |
| It showing the contribution of NFIX to muscle development and muscular dystrophies, hematopoiesis, cancer, and neural stem cell biology, highlighting the importance of this knowledge in the development of therapeutic targets. | Nuclear Factor One X in Development and Disease.
Piper M, Gronostajski R, Messina G. | 06/22/2019 |
| We identified recurrent targeting of NFIX by HPV16 insertion in anal carcinomas, supporting a role for this gene in oncogenesis | Nuclear factor I X is a recurrent target for HPV16 insertions in anal carcinomas.
Jeannot E, Harlé A, Holmes A, Sastre-Garau X. | 03/2/2019 |
| Microduplications encompassing NFIX cause intellectual disability, short stature and small head circumference. | 19p13 microduplications encompassing NFIX are responsible for intellectual disability, short stature and small head circumference.
Trimouille A, Houcinat N, Vuillaume ML, Fergelot P, Boucher C, Toutain J, Caignec CL, Vincent M, Nizon M, Andrieux J, Vanlerberghe C, Delobel B, Duban B, Mansour S, Baple E, McKeown C, Poke G, Robertshaw K, Fifield E, Fabretto A, Pecile V, Gasparini P, Carrozzi M, Lacombe D, Arveiler B, Rooryck C, Moutton S., Free PMC Article | 12/22/2018 |
| Compared to noncancerous esophageal mucosa, miR-1290 expression was upregulated, while NFIX mRNA expression was downregulated in ESCC tissues. Data suggest that the dysregulation of miR-1290-NFIX axis may play crucial roles in esophageal carcinogenesis and progression. | Prognostic value of combined and individual expression of microRNA-1290 and its target gene nuclear factor I/X in human esophageal squamous cell carcinoma.
Xie R, Wu SN, Gao CC, Yang XZ, Wang HG, Zhang JL, Yan W, Ma TH. | 06/9/2018 |
| A novel de novo pathogenic variant in the NFIX gene identified in a case of Marshall-Smith syndrome with precocious puberty and aortic root dilatation. | Marshall-Smith syndrome: Novel pathogenic variant and previously unreported associations with precocious puberty and aortic root dilatation.
Aggarwal A, Nguyen J, Rivera-Davila M, Rodriguez-Buritica D. | 09/30/2017 |
| Studies indicate the role of nuclear factor one (NFIs) as epigenetic regulators in cancer. | Nuclear factor one transcription factors as epigenetic regulators in cancer.
Fane M, Harris L, Smith AG, Piper M. | 09/23/2017 |
| Plasma miR-1914* and -1915 interact with NFIX RNA. | The Plasma microRNA miR-1914* and -1915 Suppresses Chemoresistant in Colorectal Cancer Patients by Down-regulating NFIX.
Hu J, Cai G, Xu Y, Cai S. | 10/8/2016 |