| TLR4 TIR domain and nucleolin GAR domain synergistically mediate RSV infection and induce neuronal inflammatory damage in SH-SY5Y cells. | TLR4 TIR domain and nucleolin GAR domain synergistically mediate RSV infection and induce neuronal inflammatory damage in SH-SY5Y cells.
Jiang C, Huang Y, Gui H, Liu X, Li H, Han M, Huang S. | 04/4/2024 |
| RGS6 drives cardiomyocyte death following nucleolar stress by suppressing Nucleolin/miRNA-21. | RGS6 drives cardiomyocyte death following nucleolar stress by suppressing Nucleolin/miRNA-21.
Sengar AS, Kumar M, Rai C, Chakraborti S, Kumar D, Kumar P, Mukherjee S, Mondal K, Stewart A, Maity B., Free PMC Article | 02/29/2024 |
| Structural Integrity of Nucleolin Is Required to Suppress TDP-43-Mediated Cytotoxicity in Yeast and Human Cell Models. | Structural Integrity of Nucleolin Is Required to Suppress TDP-43-Mediated Cytotoxicity in Yeast and Human Cell Models.
Peggion C, Massimino ML, Pereira D, Granuzzo S, Righetto F, Bortolotto R, Agostini J, Sartori G, Bertoli A, Lopreiato R., Free PMC Article | 01/12/2024 |
| Nucleolin; A tumor associated antigen as a potential lung cancer biomarker. | Nucleolin; A tumor associated antigen as a potential lung cancer biomarker.
Ezzatifar F, Rafiei A, Jeddi-Tehrani M. | 12/10/2022 |
| Nucleolin expression has prognostic value in neuroblastoma patients. | Nucleolin expression has prognostic value in neuroblastoma patients.
Cangelosi D, Brignole C, Bensa V, Tamma R, Malaguti F, Carlini B, Giusto E, Calarco E, Perri P, Ribatti D, Fonseca NA, Moreira JN, Eva A, Amoroso L, Conte M, Garaventa A, Sementa AR, Corrias MV, Ponzoni M, Pastorino F., Free PMC Article | 11/26/2022 |
| The nascent polypeptide-associated complex (NAC) controls translation initiation in cis by recruiting nucleolin to the encoding mRNA. | The nascent polypeptide-associated complex (NAC) controls translation initiation in cis by recruiting nucleolin to the encoding mRNA.
Zheng AJL, Thermou A, Daskalogianni C, Malbert-Colas L, Karakostis K, Le Sénéchal R, Trang Dinh V, Tovar Fernandez MC, Apcher S, Chen S, Blondel M, Fahraeus R., Free PMC Article | 10/15/2022 |
| Overexpression of Nucleolin and Associated Genes in Prostate Cancer. | Overexpression of Nucleolin and Associated Genes in Prostate Cancer.
Firlej V, Soyeux P, Nourieh M, Huet E, Semprez F, Allory Y, Londono-Vallejo A, de la Taille A, Vacherot F, Destouches D., Free PMC Article | 05/21/2022 |
| Downregulation of NCL attenuates tumor formation and growth in HeLa cells by targeting the PI3K/AKT pathway. | Downregulation of NCL attenuates tumor formation and growth in HeLa cells by targeting the PI3K/AKT pathway.
Ying J, Pan R, Tang Z, Zhu J, Ren P, Lou Y, Zhang E, Huang D, Hu P, Li D, Bao Q, Li P., Free PMC Article | 04/30/2022 |
| Nucleolin as activator of TCF7L2 in human hematopoietic stem/progenitor cells. | Nucleolin as activator of TCF7L2 in human hematopoietic stem/progenitor cells.
Reister S, Mahotka C, Grinstein E., Free PMC Article | 01/29/2022 |
| CRYbetaB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer. | CRYβB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer.
Yan Y, Narayan A, Cho S, Cheng Z, Liu JO, Zhu H, Wang G, Wharram B, Lisok A, Brummet M, Saeki H, Huang T, Gabrielson K, Gabrielson E, Cope L, Kanaan YM, Afsari A, Naab T, Yfantis HG, Ambs S, Pomper MG, Sukumar S, Merino VF., Free PMC Article | 01/1/2022 |
| Fine-Tuning of mTOR mRNA and Nucleolin Complexes by SMN. | Fine-Tuning of mTOR mRNA and Nucleolin Complexes by SMN.
Gabanella F, Barbato C, Fiore M, Petrella C, de Vincentiis M, Greco A, Minni A, Corbi N, Passananti C, Di Certo MG., Free PMC Article | 01/1/2022 |
| Cell surface Nucleolin represents a novel cellular target for neuroblastoma therapy. | Cell surface Nucleolin represents a novel cellular target for neuroblastoma therapy.
Brignole C, Bensa V, Fonseca NA, Del Zotto G, Bruno S, Cruz AF, Malaguti F, Carlini B, Morandi F, Calarco E, Perri P, Moura V, Emionite L, Cilli M, De Leonardis F, Tondo A, Amoroso L, Conte M, Garaventa A, Sementa AR, Corrias MV, Ponzoni M, Moreira JN, Pastorino F., Free PMC Article | 12/11/2021 |
| Cell surface nucleolin as active bait for nanomedicine in cancer therapy: a promising option. | Cell surface nucleolin as active bait for nanomedicine in cancer therapy: a promising option.
Ferrara B, Belbekhouche S, Habert D, Houppe C, Vallée B, Bourgoin-Voillard S, Cohen JL, Cascone I, Courty J. | 11/27/2021 |
| The Synergistic Role of Tip alpha, Nucleolin and Ras in Helicobacter pylori Infection Regulates the Cell Fate Towards Inflammation or Apoptosis. | The Synergistic Role of Tip α, Nucleolin and Ras in Helicobacter pylori Infection Regulates the Cell Fate Towards Inflammation or Apoptosis.
Mahant S, Chakraborty A, Som A, Mehra S, Das K, Mukhopadhyay AK, Gehlot V, Bose S, Das R. | 09/18/2021 |
| Targeting nucleolin by RNA G-quadruplex-forming motif. | Targeting nucleolin by RNA G-quadruplex-forming motif.
Figueiredo J, Miranda A, Lopes-Nunes J, Carvalho J, Alexandre D, Valente S, Mergny JL, Cruz C. | 09/18/2021 |
| Involvement of VCP/UFD1/Nucleolin in the viral entry of Enterovirus A species. | Involvement of VCP/UFD1/Nucleolin in the viral entry of Enterovirus A species.
Yan J, Wang M, Wang M, Dun Y, Zhu L, Yi Z, Zhang S., Free PMC Article | 08/28/2021 |
| Nucleolin regulates 14-3-3zeta mRNA and promotes cofilin phosphorylation to induce tunneling nanotube formation. | Nucleolin regulates 14-3-3ζ mRNA and promotes cofilin phosphorylation to induce tunneling nanotube formation.
Dagar S, Pushpa K, Pathak D, Samaddar S, Saxena A, Banerjee S, Mylavarapu SVS. | 06/19/2021 |
| Nucleolin Mediates LPS-induced Expression of Inflammatory Mediators and Activation of Signaling Pathways. | Nucleolin Mediates LPS-induced Expression of Inflammatory Mediators and Activation of Signaling Pathways.
Fang L, Wang KK, Huang Q, Cheng F, Huang F, Liu WW. | 06/12/2021 |
| The long noncoding RNA LUCAT1 promotes colorectal cancer cell proliferation by antagonizing Nucleolin to regulate MYC expression. | The long noncoding RNA LUCAT1 promotes colorectal cancer cell proliferation by antagonizing Nucleolin to regulate MYC expression.
Wu R, Li L, Bai Y, Yu B, Xie C, Wu H, Zhang Y, Huang L, Yan Y, Li X, Lin C., Free PMC Article | 05/22/2021 |
| Inhibition of Specificity Protein 1 Is Involved in Phloretin-Induced Suppression of Prostate Cancer. | Inhibition of Specificity Protein 1 Is Involved in Phloretin-Induced Suppression of Prostate Cancer.
Kang D, Zuo W, Wu Q, Zhu Q, Liu P., Free PMC Article | 05/1/2021 |
| Growth Factor Midkine Aggravates Pulmonary Arterial Hypertension via Surface Nucleolin. | Growth Factor Midkine Aggravates Pulmonary Arterial Hypertension via Surface Nucleolin.
Kinoshita D, Shishido T, Takahashi T, Yokoyama M, Sugai T, Watanabe K, Tamura H, Nishiyama S, Takahashi H, Arimoto T, Miyamoto T, Watanabe T, Kishida S, Kadomatsu K, Abe JI, Takeishi Y, Konta T, Kubota I, Watanabe M., Free PMC Article | 12/26/2020 |
| Study describes the molecular mechanism by which nucleolin (NCL) recognizes G-quadruplexes (G4)-containing long loops and leads to the proposal of a model implying a concerted action of RNA binding domain 2 (RBD2) and glycine/arginine (RGG) domains to achieve specific G4 recognition via a dual loop-quartet interaction. | Nucleolin Discriminates Drastically between Long-Loop and Short-Loop Quadruplexes.
Saha A, Duchambon P, Masson V, Loew D, Bombard S, Teulade-Fichou MP. | 07/11/2020 |
| CSA and CSB are positive regulators of ribosomal RNA synthesis via Ncl regulation. | Cockayne syndrome group A and B proteins function in rRNA transcription through nucleolin regulation.
Okur MN, Lee JH, Osmani W, Kimura R, Demarest TG, Croteau DL, Bohr VA., Free PMC Article | 05/23/2020 |
| Nucleolin expressed on the surface of head and neck squamous cell carcinoma cells is an active ligand for L-selectin. | Nucleolin mediates the binding of cancer cells to L-selectin under conditions of lymphodynamic shear stress.
Goldson TM, Turner KL, Huang Y, Carlson GE, Caggiano EG, Oberhauser AF, Fennewald SM, Burdick MM, Resto VA., Free PMC Article | 05/9/2020 |
| Nucleolin (NCL) is a major regulator of miR processing in response to OS and essential for the maturation of miR-93 and miR-484 that target mRNAs encoding KLF2 and eNOS. AMPK phosphorylation of NCL sequesters it in the nucleus, thereby inhibiting miR-93 and miR-484 processing and their subsequent targeting of KLF2 and eNOS mRNA. Elevated levels of miR-93 and miR-484 were found in sera of coronary artery disease patients. | Shear stress regulation of miR-93 and miR-484 maturation through nucleolin.
Gongol B, Marin T, Zhang J, Wang SC, Sun W, He M, Chen S, Chen L, Li J, Liu JH, Martin M, Han Y, Kang J, Johnson DA, Lytle C, Li YS, Huang PH, Chien S, Shyy JY., Free PMC Article | 04/11/2020 |