| Determination of Complex Formation between Drosophila Nrf2 and GATA4 Factors at Selective Chromatin Loci Demonstrates Transcription Coactivation. | Determination of Complex Formation between Drosophila Nrf2 and GATA4 Factors at Selective Chromatin Loci Demonstrates Transcription Coactivation.
Neidviecky E, Deng H., Free PMC Article | 04/12/2023 |
| Overexpression of Tinman and Pannier resulted in 20% of embryos with ectopic Hand and Sur expression. By adding MEF2 alongside Tinman and Pannier, an expansion in expression of Hand and Sur was observed. | The Drosophila Transcription Factors Tinman and Pannier Activate and Collaborate with Myocyte Enhancer Factor-2 to Promote Heart Cell Fate.
Lovato TL, Sensibaugh CA, Swingle KL, Martinez MM, Cripps RM., Free PMC Article | 05/7/2016 |
| A second 20E-mediated mechanism, which robustly affects only a subset of AMP genes, is uniquely controlled by BR-C, SRP and PNR. | Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity.
Rus F, Flatt T, Tong M, Aggarwal K, Okuda K, Kleino A, Yates E, Tatar M, Silverman N., Free PMC Article | 08/10/2013 |
| pnr appears to be highly regulated by Dpp and Brk on both the DV and AP axes during embryo patterning. | Response to the BMP gradient requires highly combinatorial inputs from multiple patterning systems in the Drosophila embryo.
Liang HL, Xu M, Chuang YC, Rushlow C., Free PMC Article | 07/21/2012 |
| Genetic interaction analysis shows that spir functionally interacts with Dorsocross, tin, and pannier to properly specify the cardiac fate. | Spire, an actin nucleation factor, regulates cell division during Drosophila heart development.
Xu P, Johnson TL, Stoller-Conrad JR, Schulz RA., Free PMC Article | 06/9/2012 |
| This study uncovers complex transcriptional interactions between the pnr isoforms and the cofactor Ush that may be important for regulation of proneural expression and thorax patterning. | Transcriptional interactions between the pannier isoforms and the cofactor U-shaped during neural development in Drosophila.
Fromental-Ramain C, Taquet N, Ramain P. | 06/18/2011 |
| Stat and Pnr represent two essential factors controlling blood cell maturation in the developing lymph gland and exert their functions both in a cell-autonomous and non-cell-autonomous manner. | JAK/STAT and the GATA factor Pannier control hemocyte maturation and differentiation in Drosophila.
Minakhina S, Tan W, Steward R., Free PMC Article | 05/28/2011 |
| Dorsal eye selector pannier (pnr) suppresses the eye fate to define dorsal margin of the Drosophila eye | Dorsal eye selector pannier (pnr) suppresses the eye fate to define dorsal margin of the Drosophila eye.
Oros SM, Tare M, Kango-Singh M, Singh A., Free PMC Article | 11/6/2010 |
| Pnr is essential for early cardiac progenitor formation and also plays an important role in maintaining proper heart function. | Partial loss of GATA factor Pannier impairs adult heart function in Drosophila.
Qian L, Bodmer R., Free PMC Article | 01/21/2010 |
| show that the dual function of pnr during regulation of wingless is achieved by one isoform repressing expression of the morphogen in the dorsal-most region of the disc while the other laterally promotes activation of the notal wingless expression | pannier encodes two structurally related isoforms that are differentially expressed during Drosophila development and display distinct functions during thorax patterning.
Fromental-Ramain C, Vanolst L, Delaporte C, Ramain P. | 01/21/2010 |
| Pnr is positevely regulated by Tou during neuronal development. | Toutatis, a TIP5-related protein, positively regulates Pannier function during Drosophila neural development.
Vanolst L, Fromental-Ramain C, Ramain P. | 01/21/2010 |
| Pannier and Chip play an essential role during repression of proneural gene expression. | Enhancer-promoter communication mediated by Chip during Pannier-driven proneural patterning is regulated by Osa.
Heitzler P, Vanolst L, Biryukova I, Ramain P., Free PMC Article | 01/21/2010 |
| manipulation of pannier activity in either germ layer affects cardiac specification, suggesting that its function is required in both the mesoderm and the ectoderm | Gata factor Pannier is required to establish competence for heart progenitor formation.
Klinedinst SL, Bodmer R. | 01/21/2010 |
| Data show that pannier acts upstream of pointed P2 in a developmental pathway in which pannier promotes cardiac mesoderm formation, and pointed acts subsequently to distinguish between cardioblast and pericardial cell fates. | pannier and pointedP2 act sequentially to regulate Drosophila heart development.
Alvarez AD, Shi W, Wilson BA, Skeath JB. | 01/21/2010 |