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    E envelope protein [ Severe acute respiratory syndrome coronavirus 2 ]

    Gene ID: 43740570, updated on 8-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    A short sequence in the tail of SARS-CoV-2 envelope protein controls accessibility of its PDZ-binding motif to the cytoplasm.

    A short sequence in the tail of SARS-CoV-2 envelope protein controls accessibility of its PDZ-binding motif to the cytoplasm.
    Neitthoffer B, Alvarez F, Larrous F, Caillet-Saguy C, Etienne-Manneville S, Boëda B., Free PMC Article

    02/9/2024
    Atomic structure of the open SARS-CoV-2 E viroporin.

    Atomic structure of the open SARS-CoV-2 E viroporin.
    Medeiros-Silva J, Dregni AJ, Somberg NH, Duan P, Hong M., Free PMC Article

    11/29/2023
    The Cytoplasmic Domain of the SARS-CoV-2 Envelope Protein Assembles into a beta-Sheet Bundle in Lipid Bilayers.

    The Cytoplasmic Domain of the SARS-CoV-2 Envelope Protein Assembles into a β-Sheet Bundle in Lipid Bilayers.
    Dregni AJ, McKay MJ, Surya W, Queralt-Martin M, Medeiros-Silva J, Wang HK, Aguilella V, Torres J, Hong M., Free PMC Article

    03/3/2023
    SARS-CoV-2 Harnesses Host Translational Shutoff and Autophagy To Optimize Virus Yields: the Role of the Envelope (E) Protein.

    SARS-CoV-2 Harnesses Host Translational Shutoff and Autophagy To Optimize Virus Yields: the Role of the Envelope (E) Protein.
    Waisner H, Grieshaber B, Saud R, Henke W, Stephens EB, Kalamvoki M., Free PMC Article

    02/27/2023
    Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.

    Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
    Vann KR, Acharya A, Jang SM, Lachance C, Zandian M, Holt TA, Smith AL, Pandey K, Durden DL, El-Gamal D, Côté J, Byrareddy SN, Kutateladze TG., Free PMC Article

    09/17/2022
    SARS-CoV-2 Envelope (E) Protein Binds and Activates TLR2 Pathway: A Novel Molecular Target for COVID-19 Interventions.

    SARS-CoV-2 Envelope (E) Protein Binds and Activates TLR2 Pathway: A Novel Molecular Target for COVID-19 Interventions.
    Planès R, Bert JB, Tairi S, BenMohamed L, Bahraoui E., Free PMC Article

    06/11/2022
    Structure and dynamics of the SARS-CoV-2 envelope protein monomer.

    Structure and dynamics of the SARS-CoV-2 envelope protein monomer.
    Kuzmin A, Orekhov P, Astashkin R, Gordeliy V, Gushchin I.

    04/30/2022
    Surface Proteins of SARS-CoV-2 Drive Airway Epithelial Cells to Induce IFN-Dependent Inflammation.

    Surface Proteins of SARS-CoV-2 Drive Airway Epithelial Cells to Induce IFN-Dependent Inflammation.
    Anand G, Perry AM, Cummings CL, St Raymond E, Clemens RA, Steed AL., Free PMC Article

    01/8/2022
    Small Structural Proteins E and M Render the SARS-CoV-2 Pseudovirus More Infectious and Reveal the Phenotype of Natural Viral Variants.

    Small Structural Proteins E and M Render the SARS-CoV-2 Pseudovirus More Infectious and Reveal the Phenotype of Natural Viral Variants.
    Wang HI, Chuang ZS, Kao YT, Lin YL, Liang JJ, Liao CC, Liao CL, Lai MMC, Yu CY., Free PMC Article

    09/4/2021
    TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines.

    TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines.
    Zheng M, Karki R, Williams EP, Yang D, Fitzpatrick E, Vogel P, Jonsson CB, Kanneganti TD., Free PMC Article

    07/10/2021
    Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.

    Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
    Javorsky A, Humbert PO, Kvansakul M., Free PMC Article

    06/26/2021
    Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1.

    Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1.
    Chai J, Cai Y, Pang C, Wang L, McSweeney S, Shanklin J, Liu Q., Free PMC Article

    06/19/2021
    Characterization of the SARS-CoV-2 E Protein: Sequence, Structure, Viroporin, and Inhibitors.

    Characterization of the SARS-CoV-2 E Protein: Sequence, Structure, Viroporin, and Inhibitors.
    Cao Y, Yang R, Lee I, Zhang W, Sun J, Wang W, Meng X., Free PMC Article

    06/5/2021
    Evolution of SARS-CoV-2 Envelope, Membrane, Nucleocapsid, and Spike Structural Proteins from the Beginning of the Pandemic to September 2020: A Global and Regional Approach by Epidemiological Week.

    Evolution of SARS-CoV-2 Envelope, Membrane, Nucleocapsid, and Spike Structural Proteins from the Beginning of the Pandemic to September 2020: A Global and Regional Approach by Epidemiological Week.
    Troyano-Hernáez P, Reinosa R, Holguín Á., Free PMC Article

    02/20/2021
    SARS-CoV2 envelope protein: non-synonymous mutations and its consequences.

    SARS-CoV2 envelope protein: non-synonymous mutations and its consequences.
    Hassan SS, Choudhury PP, Roy B., Free PMC Article

    01/2/2021
    Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers.

    Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers.
    Mandala VS, McKay MJ, Shcherbakov AA, Dregni AJ, Kolocouris A, Hong M., Free PMC Article

    12/19/2020
    A SARS-CoV-2 variant with the 12-bp deletion at E gene.

    A SARS-CoV-2 variant with the 12-bp deletion at E gene.
    Sun YS, Xu F, An Q, Chen C, Yang ZN, Lu HJ, Chen JC, Yao PP, Jiang JM, Zhu HP., Free PMC Article

    11/21/2020
    Host-membrane interacting interface of the SARS coronavirus envelope protein: Immense functional potential of C-terminal domain.

    Host-membrane interacting interface of the SARS coronavirus envelope protein: Immense functional potential of C-terminal domain.
    Mukherjee S, Bhattacharyya D, Bhunia A., Free PMC Article

    10/31/2020
    Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein.

    Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein.
    Toto A, Ma S, Malagrinò F, Visconti L, Pagano L, Stromgaard K, Gianni S., Free PMC Article

    10/10/2020
    Functional Pangenome Analysis Shows Key Features of E Protein Are Preserved in SARS and SARS-CoV-2.

    Functional Pangenome Analysis Shows Key Features of E Protein Are Preserved in SARS and SARS-CoV-2.
    Alam I, Kamau AA, Kulmanov M, Jaremko Ł, Arold ST, Pain A, Gojobori T, Duarte CM., Free PMC Article

    09/5/2020
    In this report, a structural comparison between the Sars-CoV-2 Envelope and Membrane proteins from different human isolates with homologous proteins from closely related viruses is described. The analyses here reported show the high structural similarity of Envelope and Membrane proteins to the counterparts from Pangolin and Bat coronavirus isolates.

    Sars-CoV-2 Envelope and Membrane Proteins: Structural Differences Linked to Virus Characteristics?
    Bianchi M, Benvenuto D, Giovanetti M, Angeletti S, Ciccozzi M, Pascarella S., Free PMC Article

    07/11/2020
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