HDAC1/2 and HDAC3 play distinct roles in controlling adult Meibomian gland homeostasis. | HDAC1/2 and HDAC3 play distinct roles in controlling adult Meibomian gland homeostasis. Zhu X, Xu M, Millar SE., | 06/27/2024 |
Unveiling the role of HP1alpha-HDAC1-STAT1 axis as a therapeutic target for HP1alpha-positive intrahepatic cholangiocarcinoma. | Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma. Xiong F, Wang D, Xiong W, Wang X, Huang WH, Wu GH, Liu WZ, Wang Q, Chen JS, Kuai YY, Wang B, Chen YJ., Free PMC Article | 06/6/2024 |
Zinc finger protein 36 like 2-histone deacetylase 1 axis is involved in the bone responses to mechanical stress. | Zinc finger protein 36 like 2-histone deacetylase 1 axis is involved in the bone responses to mechanical stress. Wang B, Wang W, Li J, Li J. | 05/29/2024 |
Attenuation of neuronal ferroptosis in intracerebral hemorrhage by inhibiting HDAC1/2: Microglial heterogenization via the Nrf2/HO1 pathway. | Attenuation of neuronal ferroptosis in intracerebral hemorrhage by inhibiting HDAC1/2: Microglial heterogenization via the Nrf2/HO1 pathway. Jiang Z, Yang H, Ni W, Gao X, Pei X, Jiang H, Su J, Weng R, Fei Y, Gao Y, Gu Y., Free PMC Article | 03/27/2024 |
HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-alpha5beta1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling. | HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling. Terri M, Sandoval P, Bontempi G, Montaldo C, Tomero-Sanz H, de Turris V, Trionfetti F, Pascual-Antón L, Clares-Pedrero I, Battistelli C, Valente S, Zwergel C, Mai A, Rosanò L, Del Pozo MÁ, Sánchez-Álvarez M, Cabañas C, Tripodi M, López-Cabrera M, Strippoli R., Free PMC Article | 02/12/2024 |
Hdac1 and Hdac2 positively regulate Notch1 gain-of-function pathogenic signaling in committed osteoblasts of male mice. | Hdac1 and Hdac2 positively regulate Notch1 gain-of-function pathogenic signaling in committed osteoblasts of male mice. Torres HM, Hinojosa L, VanCleave AM, Rodezno T, Westendorf JJ, Tao J., | 02/6/2024 |
C/EBPalpha alleviates hepatic ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress via HDAC1-mediated deacetylation of ATF4. | C/EBPα alleviates hepatic ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress via HDAC1-mediated deacetylation of ATF4. Li R, Yang L, Li S, Chen S, Ren Y, Shen L, Dong L, Chen X, Li J, Xu M. | 01/29/2024 |
HDAC1 inhibits beige adipocyte-mediated thermogenesis through histone crotonylation of Pgc1a/Ucp1. | HDAC1 inhibits beige adipocyte-mediated thermogenesis through histone crotonylation of Pgc1a/Ucp1. Tian D, Zeng X, Gong Y, Zheng Y, Zhang J, Wu Z. | 10/10/2023 |
RNF157 attenuates CD4[+] T cell-mediated autoimmune response by promoting HDAC1 ubiquitination and degradation. | RNF157 attenuates CD4(+) T cell-mediated autoimmune response by promoting HDAC1 ubiquitination and degradation. Wang P, Zhao J, Tan Y, Sheng J, He S, Chen Y, Nie D, You X, Luo J, Zhang Y, Hu S., Free PMC Article | 08/31/2023 |
Pathologic HDAC1/c-Myc signaling axis is responsible for angiotensinogen transcription and hypertension induced by high-fat diet. | Pathologic HDAC1/c-Myc signaling axis is responsible for angiotensinogen transcription and hypertension induced by high-fat diet. Youn EK, Cho HM, Jung JK, Yoon GE, Eto M, Kim JI. | 06/26/2023 |
Histone deacetylase 1 regulates haloperidol-induced motor side effects in aged mice. | Histone deacetylase 1 regulates haloperidol-induced motor side effects in aged mice. McClarty BM, Chakraborty S, Rodriguez G, Dong H., Free PMC Article | 05/18/2023 |
Endothelial HDAC1-ZEB2-NuRD Complex Drives Aortic Aneurysm and Dissection Through Regulation of Protein S-Sulfhydration. | Endothelial HDAC1-ZEB2-NuRD Complex Drives Aortic Aneurysm and Dissection Through Regulation of Protein S-Sulfhydration. Luo S, Kong C, Zhao S, Tang X, Wang Y, Zhou X, Li R, Liu X, Tang X, Sun S, Xie W, Zhang ZR, Jing Q, Gu A, Chen F, Wang D, Wang H, Han Y, Xie L, Ji Y. | 05/12/2023 |
miR-34a-5p facilitates osteogenic differentiation of bone marrow mesenchymal stem cells and modulates bone metabolism by targeting HDAC1 and promoting ER-alpha transcription. | miR-34a-5p facilitates osteogenic differentiation of bone marrow mesenchymal stem cells and modulates bone metabolism by targeting HDAC1 and promoting ER-α transcription. Sun D, Chen Y, Liu X, Huang G, Cheng G, Yu C, Fang J. | 03/8/2023 |
Cell Cycle and Senescence Regulation by Podocyte Histone Deacetylase 1 and 2. | Cell Cycle and Senescence Regulation by Podocyte Histone Deacetylase 1 and 2. Medina Rangel PX, Cross E, Liu C, Pedigo CE, Tian X, Gutiérrez-Calabrés E, Nagata S, Priyadarshini A, Lerner G, Bunda P, Perincheri S, Gu J, Zhao H, Wang Y, Inoue K, Ishibe S., Free PMC Article | 03/6/2023 |
Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons. | Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons. Zheng HL, Sun SY, Jin T, Zhang M, Zeng Y, Liu Q, Yang K, Wei R, Pan Z, Lin F., Free PMC Article | 02/12/2023 |
5-Methylcytosine and 5-Hydroxymethylcytosine in Scrapie-Infected Sheep and Mouse Brain Tissues. | 5-Methylcytosine and 5-Hydroxymethylcytosine in Scrapie-Infected Sheep and Mouse Brain Tissues. Hernaiz A, Sentre S, Betancor M, López-Pérez Ó, Salinas-Pena M, Zaragoza P, Badiola JJ, Toivonen JM, Bolea R, Martín-Burriel I., Free PMC Article | 02/4/2023 |
Histone deacetylases 1 and 2 target gene regulatory networks of nephron progenitors to control nephrogenesis. | Histone deacetylases 1 and 2 target gene regulatory networks of nephron progenitors to control nephrogenesis. Liu H, Ngo NYN, Herzberger KF, Gummaraju M, Hilliard S, Chen CH. | 12/10/2022 |
ITGB4 deficiency induces DNA damage by downregulating HDAC1 in airway epithelial cells under stress stimulation. | ITGB4 deficiency induces DNA damage by downregulating HDAC1 in airway epithelial cells under stress stimulation. Xu K, Yao Y, Liu H, Yang M, Yuan L, Du X, Yang Y, Qin L, Wang W, Zhou K, Wu X, Liu C. | 10/29/2022 |
HDAC1 Promotes Myocardial Fibrosis in Diabetic Cardiomyopathy by Inhibiting BMP-7 Transcription Through Histone Deacetylation. | HDAC1 Promotes Myocardial Fibrosis in Diabetic Cardiomyopathy by Inhibiting BMP-7 Transcription Through Histone Deacetylation. Ouyang C, Huang L, Ye X, Ren M, Han Z. | 10/29/2022 |
HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia. | HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia. Gregoricchio S, Polit L, Esposito M, Berthelet J, Delestré L, Evanno E, Diop M, Gallais I, Aleth H, Poplineau M, Zwart W, Rosenbauer F, Rodrigues-Lima F, Duprez E, Boeva V, Guillouf C., Free PMC Article | 08/20/2022 |
The lysine deacetylase activity of histone deacetylases 1 and 2 is required to safeguard zygotic genome activation in mice and cattle. | The lysine deacetylase activity of histone deacetylases 1 and 2 is required to safeguard zygotic genome activation in mice and cattle. Dang Y, Li S, Zhao P, Xiao L, Wang L, Shi Y, Luo L, Wang S, Wang H, Zhang K. | 06/11/2022 |
HDAC1 expression is positively correlated with NADPH oxidase 4-mediated oxidative stress in a mouse model of traumatic brain injury. | HDAC1 expression is positively correlated with NADPH oxidase 4-mediated oxidative stress in a mouse model of traumatic brain injury. Chen Y, Lu Y, Xu S, Liu M, Chen W, Zhang Y, Wei L, Zhong C. | 05/14/2022 |
Downregulation of Sp1 Inhibits the Expression of HDAC1/SOX10 to Alleviate Neuropathic Pain-like Behaviors after Spinal Nerve Ligation in Mice. | Downregulation of Sp1 Inhibits the Expression of HDAC1/SOX10 to Alleviate Neuropathic Pain-like Behaviors after Spinal Nerve Ligation in Mice. Xie Y, Li Z, Xu H, Ma J, Li T, Shi C, Jin J. | 05/14/2022 |
Astrocytic c-Jun N-terminal kinase-histone deacetylase-2 cascade contributes to glutamate transporter-1 decrease and mechanical allodynia following peripheral nerve injury in rats. | Astrocytic c-Jun N-terminal kinase-histone deacetylase-2 cascade contributes to glutamate transporter-1 decrease and mechanical allodynia following peripheral nerve injury in rats. Lu R, Cui SS, Wang XX, Chen L, Liu F, Gao J, Wang W. | 03/26/2022 |
Kidney cell type-specific changes in the chromatin and transcriptome landscapes following epithelial Hdac1 and Hdac2 knockdown. | Kidney cell type-specific changes in the chromatin and transcriptome landscapes following epithelial Hdac1 and Hdac2 knockdown. Hyndman KA, Crossman DK., Free PMC Article | 03/26/2022 |