| Identification of two putative HOW Response Elements within the dgrasp open reading frame for binding to Held Out Wings (HOW). | The Drosophila RNA-binding protein HOW controls the stability of dgrasp mRNA in the follicular epithelium.
Giuliani G, Giuliani F, Volk T, Rabouille C., Free PMC Article | 04/19/2014 |
| HOW is required for SXL to retain msl2 transcripts in the nucleus | Sex-lethal promotes nuclear retention of msl2 mRNA via interactions with the STAR protein HOW.
Graindorge A, Carré C, Gebauer F., Free PMC Article | 08/31/2013 |
| Spatiotemporal regulation of HOW expression is required to specify the four spermatogonial transit-amplifying divisions. | HOW is required for stem cell maintenance in the Drosophila testis and for the onset of transit-amplifying divisions.
Monk AC, Siddall NA, Volk T, Fraser B, Quinn LM, McLaughlin EA, Hime GR. | 04/29/2013 |
| MAPK/ERK-dependent phosphorylation of HOW promotes the formation of HOW dimers and thus enhances its activity in controlling mRNA levels of key muscle-specific genes | Phosphorylation of the Drosophila melanogaster RNA-binding protein HOW by MAPK/ERK enhances its dimerization and activity.
Nir R, Grossman R, Paroush Z, Volk T., Free PMC Article | 09/8/2012 |
| HOW has different roles in male and female Drosophila germline differentiation | Differential roles of HOW in male and female Drosophila germline differentiation.
Monk AC, Siddall NA, Fraser B, McLaughlin EA, Hime GR., Free PMC Article | 07/21/2012 |
| The regulation of glial-specific splicing of Neurexin IV requires HOW and Cdk12 activity. | The regulation of glial-specific splicing of Neurexin IV requires HOW and Cdk12 activity.
Rodrigues F, Thuma L, Klämbt C. | 06/9/2012 |
| suggest that HOW(L) enhances the sensitivity of MG cells to apoptotic signals by reducing the levels of diap1 in these cells in, demonstrating a novel mode of regulation of PCD at the mRNA level | Enhanced sensitivity of midline glial cells to apoptosis is achieved by HOW(L)-dependent repression of Diap1.
Reuveny A, Elhanany H, Volk T. | 01/21/2010 |
| The Drosophila TGFbeta homolog, dpp is a novel direct target for HOW negative regulation in the wing imaginal disc. | Dissection of the target specificity of the RNA-binding protein HOW reveals dpp mRNA as a novel HOW target.
Israeli D, Nir R, Volk T. | 01/21/2010 |
| Four mRNAs were found to be specifically elevated in the mesoderm of how germline clone embryos, and to exhibit specific binding to HOW via their 3' UTRs. | Post-transcriptional repression of the Drosophila midkine and pleiotrophin homolog miple by HOW is essential for correct mesoderm spreading.
Toledano-Katchalski H, Nir R, Volohonsky G, Volk T. | 01/21/2010 |
| Cell divisions in the drosophila embryonic mesoderm are repressed via posttranscriptional regulation of string/cdc25 by Held Out Wing protein. | Cell divisions in the drosophila embryonic mesoderm are repressed via posttranscriptional regulation of string/cdc25 by HOW.
Nabel-Rosen H, Toledano-Katchalski H, Volohonsky G, Volk T. | 01/21/2010 |
| isoforms of the Drosophila RNA binding protein, how, act in opposing directions to regulate tendon cell differentiation | Two isoforms of the Drosophila RNA binding protein, how, act in opposing directions to regulate tendon cell differentiation.
Nabel-Rosen H, Volohonsky G, Reuveny A, Zaidel-Bar R, Volk T. | 01/21/2010 |