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    MET MET proto-oncogene, receptor tyrosine kinase [ Homo sapiens (human) ]

    Gene ID: 4233, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The PTPRZ1-MET/STAT3/ISG20 axis in glioma stem-like cells modulates tumor-associated macrophage polarization.

    The PTPRZ1-MET/STAT3/ISG20 axis in glioma stem-like cells modulates tumor-associated macrophage polarization.
    Wang Y, Suo J, Wang Z, Ran K, Tian Y, Han W, Liu Y, Peng X.

    11/5/2024
    Single-molecule imaging and molecular dynamics simulations reveal early activation of the MET receptor in cells.

    Single-molecule imaging and molecular dynamics simulations reveal early activation of the MET receptor in cells.
    Li Y, Arghittu SM, Dietz MS, Hella GJ, Haße D, Ferraris DM, Freund P, Barth HD, Iamele L, de Jonge H, Niemann HH, Covino R, Heilemann M., Free PMC Article

    11/5/2024
    MET exon 14 skipping mutations in non-small-cell lung cancer: real-world data from the Italian biomarker ATLAS database.

    MET exon 14 skipping mutations in non-small-cell lung cancer: real-world data from the Italian biomarker ATLAS database.
    Reale ML, Passiglia F, Cappuzzo F, Minuti G, Occhipinti M, Bulotta A, Delmonte A, Sini C, Galetta D, Roca E, Pelizzari G, Cortinovis D, Gariazzo E, Pilotto S, Citarella F, Bria E, Muscolino P, Pozzessere D, Carta A, Pignataro D, Calvetti L, Leone F, Banini M, Di Micco C, Baldini E, Favaretto A, Malapelle U, Novello S, Pasello G, Tiseo M., Free PMC Article

    10/3/2024
    Differential Immune Checkpoint Protein Expression in HNSCC: The Role of HGF/MET Signaling.

    Differential Immune Checkpoint Protein Expression in HNSCC: The Role of HGF/MET Signaling.
    Boschert V, Boenke J, Böhm AK, Teusch J, Steinacker V, Straub A, Hartmann S., Free PMC Article

    07/18/2024
    PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility.

    PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility.
    Jing N, Du X, Liang Y, Tao Z, Bao S, Xiao H, Dong B, Gao WQ, Fang YX., Free PMC Article

    07/17/2024
    Deregulated immune cell recruitment orchestrated by c-MET impairs pulmonary inflammation and fibrosis.

    Deregulated immune cell recruitment orchestrated by c-MET impairs pulmonary inflammation and fibrosis.
    Barbosa-Matos C, Borges-Pereira C, Libório-Ramos S, Fernandes R, Oliveira M, Mendes-Frias A, Silvestre R, Osório NS, Bastos HN, Santos RF, Guimarães S, Morais A, Mazzone M, Carvalho A, Cunha C, Costa S., Free PMC Article

    07/11/2024
    Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1/2 in HCT116 colorectal cancer cells.

    Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1/2 in HCT116 colorectal cancer cells.
    Garcia Delgado L, Derome A, Longpré S, Giroux-Dansereau M, Basbous G, Lavoie C, Saucier C, Denault JB., Free PMC Article

    06/30/2024
    MET alterations in advanced non-small cell lung cancer.

    MET alterations in advanced non-small cell lung cancer.
    Chagas GCL, Rangel AR, El Osta B.

    06/29/2024
    MET overexpression correlated with prognosis of EGFR-mutant treatment-naive advanced lung adenocarcinoma: a real-world retrospective study.

    MET overexpression correlated with prognosis of EGFR-mutant treatment‑naïve advanced lung adenocarcinoma: a real‑world retrospective study.
    Wang N, Zhang Y, Wu J, Zhu Y, Wu Y, Huang B, Zhang R, Fan J, Nie X.

    06/27/2024
    Clinical, pathologic, and genomic characteristics of two pediatric glioneuronal tumors with a CLIP2::MET fusion.

    Clinical, pathologic, and genomic characteristics of two pediatric glioneuronal tumors with a CLIP2::MET fusion.
    Chapman N, Greenwald J, Suddock J, Xu D, Markowitz A, Humphrey M, Cotter JA, Krieger MD, Hawes D, Ji J., Free PMC Article

    05/1/2024
    Receptor tyrosine kinase gene expression profiling of orbital rhabdomyosarcoma unveils MET as a potential biomarker and therapeutic target.

    Receptor tyrosine kinase gene expression profiling of orbital rhabdomyosarcoma unveils MET as a potential biomarker and therapeutic target.
    Chauhan S, Sen S, Irshad K, Kashyap S, Pushker N, Meel R, Sharma MC.

    02/5/2024
    MET Fusions in NSCLC: Clinicopathologic Features and Response to MET Inhibition.

    MET Fusions in NSCLC: Clinicopathologic Features and Response to MET Inhibition.
    Riedel R, Fassunke J, Scheel AH, Scheffler M, Heydt C, Nogova L, Michels S, Fischer RN, Eisert A, Scharpenseel H, John F, Ruge L, Schaufler D, Siemanowski J, Ihle MA, Wagener-Ryczek S, Pappesch R, Rehker J, Bunck A, Kobe C, Keil F, Merkelbach-Bruse S, Büttner R, Wolf J.

    01/15/2024
    Up-regulation by overexpression of c-MET in fibroblastic foci of usual interstitial pneumonia.

    Up-regulation by overexpression of c-MET in fibroblastic foci of usual interstitial pneumonia.
    Melocchi L, Cervi G, Sartori G, Gandolfi L, Jocollé G, Cavazza A, Rossi G., Free PMC Article

    01/11/2024
    [Chinese expert consensus on MET immunohistochemistry detection and interpretation standards for non-small cell lung cancer(2023 version)].

    [Chinese expert consensus on MET immunohistochemistry detection and interpretation standards for non-small cell lung cancer(2023 version)].
    Standardization Interpretation Expert Committee of MET immunohistochemistry, Molecular Pathology Collaboration Group of Tumor Pathology Committee of Chinese Anti-Cancer Association.

    12/4/2023
    Real-world analysis of MET exon 14 mutations in non-small cell lung cancer: a retrospective study from two Swedish hospitals.

    Real-world analysis of MET exon 14 mutations in non-small cell lung cancer: a retrospective study from two Swedish hospitals.
    Skribek M, Brunnström H, Oskarsdottir G, Portu Grivé M, Aricak O, Planck M, Jatta K, Naserhojati H, Haglund de Flon F, Ekman S.

    11/30/2023
    Role of hypoxia on microRNA-dependant regulation of HGFA - HGF - c-Met signalling pathway in human progenitor and mature endothelial cells.

    Role of hypoxia on microRNA-dependant regulation of HGFA - HGF - c-Met signalling pathway in human progenitor and mature endothelial cells.
    Tokarski M, Cierzniak A, Baczynska D.

    11/13/2023
    PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target.

    PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target.
    Singh S, Yeat NY, Wang YT, Lin SY, Kuo IY, Wu KP, Wang WJ, Wang WC, Su WC, Wang YC, Chen RH., Free PMC Article

    11/2/2023
    c-Met is a chimeric antigen receptor T-cell target for treating recurrent nasopharyngeal carcinoma.

    c-Met is a chimeric antigen receptor T-cell target for treating recurrent nasopharyngeal carcinoma.
    Huo Q, Lv J, Zhang J, Huang H, Hu H, Zhao Y, Zhang X, Wang Y, Zhou Y, Qiu J, Ye Y, Huang A, Chen Y, Qin L, Qin D, Li P, Cai G.

    10/26/2023
    HGF-Based CAR-T Cells Target Hepatocellular Carcinoma Cells That Express High Levels of c-Met.

    HGF-Based CAR-T Cells Target Hepatocellular Carcinoma Cells That Express High Levels of c-Met.
    Ma H, Wei W, Liang D, Xu X, Yang D, Wang Q, Wang Y, Wei Q, Sun B, Zhao X.

    10/5/2023
    c-Met activation promotes extravasation of hepatocellular carcinoma cells into 3D-cultured hepatocyte cells in lab-on-a-chip device.

    c-Met activation promotes extravasation of hepatocellular carcinoma cells into 3D-cultured hepatocyte cells in lab-on-a-chip device.
    Bagci G, Comez D, Topel H, Yilmaz Y, Bagirsakci E, Gunes A, Batı Ayaz G, Tahmaz I, Bilgen M, Solmaz G, Pesen Okvur D, Atabey N.

    09/13/2023
    MET Exon 14 Skipping in NSCLC: A Systematic Literature Review of Epidemiology, Clinical Characteristics, and Outcomes.

    MET Exon 14 Skipping in NSCLC: A Systematic Literature Review of Epidemiology, Clinical Characteristics, and Outcomes.
    Mazieres J, Vioix H, Pfeiffer BM, Campden RI, Chen Z, Heeg B, Cortot AB.

    09/6/2023
    Adaptive c-Met-PLXDC2 Signaling Axis Mediates Cancer Stem Cell Plasticity to Confer Radioresistance-associated Aggressiveness in Head and Neck Cancer.

    Adaptive c-Met-PLXDC2 Signaling Axis Mediates Cancer Stem Cell Plasticity to Confer Radioresistance-associated Aggressiveness in Head and Neck Cancer.
    Lang L, Chen F, Li Y, Shay C, Yang F, Dan H, Chen ZG, Saba NF, Teng Y., Free PMC Article

    08/10/2023
    Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis.

    Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis.
    Zhou Y, Cui G, Xu H, Chun J, Yang D, Zhang Z, Yang L, Wang J, Wan M, Calvisi DF, Lin S, Chen X, Wang H., Free PMC Article

    08/2/2023
    Low co-expression of PD-L1 and oncogenic receptor tyrosine kinases HER2 and cMET in urothelial carcinoma is associated with discordant expression between primary and metastatic sites.

    Low co-expression of PD-L1 and oncogenic receptor tyrosine kinases HER2 and cMET in urothelial carcinoma is associated with discordant expression between primary and metastatic sites.
    Burgess EF, Livasy CA, Symanowski JT, Matulay JT, Grigg CM, Clark PE, Raghavan D.

    08/1/2023
    Molecular characterization of MET fusions from a large real-world Chinese population: A multicenter study.

    Molecular characterization of MET fusions from a large real-world Chinese population: A multicenter study.
    Xia H, Zhang J, Chen T, Wang M, Chen D, Si T, Liu Y., Free PMC Article

    07/27/2023
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