| Genetic polymorphisms of pri-let-7f, gene-environment and gene-gene interactions, and associations with ischemic stroke risk in Liaoning Province. | Genetic polymorphisms of pri-let-7f, gene-environment and gene-gene interactions, and associations with ischemic stroke risk in Liaoning Province.
Qiu L, Wang Y, Liu F, Deng S, He Z, Zheng W, Wang Y., Free PMC Article | 08/25/2023 |
| Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques. | Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques.
Egea V, Megens RTA, Santovito D, Wantha S, Brandl R, Siess W, Khani S, Soehnlein O, Bartelt A, Weber C, Ries C., Free PMC Article | 03/22/2023 |
| Hsa-let-7f-1-3p targeting the circadian gene Bmal1 mediates intervertebral disc degeneration by regulating autophagy. | Hsa-let-7f-1-3p targeting the circadian gene Bmal1 mediates intervertebral disc degeneration by regulating autophagy.
Mei L, Zheng Y, Gao X, Ma T, Xia B, Hao Y, Wei B, Wei Y, Luo Z, Huang J. | 12/3/2022 |
| Identification of let-7f and miR-338 as plasma-based biomarkers for sporadic amyotrophic lateral sclerosis using meta-analysis and empirical validation. | Identification of let-7f and miR-338 as plasma-based biomarkers for sporadic amyotrophic lateral sclerosis using meta-analysis and empirical validation.
Daneshafrooz N, Joghataei MT, Mehdizadeh M, Alavi A, Barati M, Panahi B, Teimourian S, Zamani B., Free PMC Article | 03/12/2022 |
| Circ_0085289 Alleviates the Progression of Periodontitis by Regulating let-7f-5p/SOCS6 Pathway. | Circ_0085289 Alleviates the Progression of Periodontitis by Regulating let-7f-5p/SOCS6 Pathway.
Du W, Wang L, Liao Z, Wang J. | 12/25/2021 |
| Downregulation of microRNA let-7f mediated the Adriamycin resistance in leukemia cell line. | Downregulation of microRNA let-7f mediated the Adriamycin resistance in leukemia cell line.
Cao YX, Wen F, Luo ZY, Long XX, Luo C, Liao P, Li JJ. | 07/17/2021 |
| Identification of Let-7f-5p as a novel biomarker of recurrence in non-muscle invasive bladder cancer. | Identification of Let-7f-5p as a novel biomarker of recurrence in non-muscle invasive bladder cancer.
Shee K, Seigne JD, Karagas MR, Marsit CJ, Hinds JW, Schned AR, Pettus JR, Armstrong DA, Miller TW, Andrew AS. | 06/12/2021 |
| let7f5p attenuates inflammatory injury in in vitro pneumonia models by targeting MAPK6. | let7f‑5p attenuates inflammatory injury in in vitro pneumonia models by targeting MAPK6.
Xu L, Song Q, Ouyang Z, Zhang X, Zhang C., Free PMC Article | 05/8/2021 |
| Reduced Let-7f in Bone Marrow-Derived Mesenchymal Stem Cells Triggers Treg/Th17 Imbalance in Patients With Systemic Lupus Erythematosus. | Reduced Let-7f in Bone Marrow-Derived Mesenchymal Stem Cells Triggers Treg/Th17 Imbalance in Patients With Systemic Lupus Erythematosus.
Geng L, Tang X, Wang S, Sun Y, Wang D, Tsao BP, Feng X, Sun L., Free PMC Article | 03/27/2021 |
| Hypoxia-induced let-7f-5p/TARBP2 feedback loop regulates osteosarcoma cell proliferation and invasion by inhibiting the Wnt signaling pathway. | Hypoxia-induced let-7f-5p/TARBP2 feedback loop regulates osteosarcoma cell proliferation and invasion by inhibiting the Wnt signaling pathway.
Chen G, Gu H, Fang T, Zhou K, Xu J, Yin X., Free PMC Article | 02/27/2021 |
| let-7f-5p functions as a potential inhibitor of Th17 differentiation in the pathogenesis of multiple sclerosis by targeting STAT3 | Let-7f-5p suppresses Th17 differentiation via targeting STAT3 in multiple sclerosis.
Li ZH, Wang YF, He DD, Zhang XM, Zhou YL, Yue H, Huang S, Fu Z, Zhang LY, Mao ZQ, Li S, Zhang CY, Chen X, Fu J., Free PMC Article | 07/25/2020 |
| Significant levels of circulating let-7f (p = 0.048) were found in Abdominal Aortic Aneurysm patients compared to peripheral arterial disease patients with no significant correlation with aortic diameter (R(2) = 0.03). | Let-7f: A New Potential Circulating Biomarker Identified by miRNA Profiling of Cells Isolated from Human Abdominal Aortic Aneurysm.
Spear R, Boytard L, Blervaque R, Chwastyniak M, Hot D, Vanhoutte J, Lamblin N, Amouyel P, Pinet F., Free PMC Article | 04/4/2020 |
| Study in human small airway epithelial cells (HSAEC) and human pulmonary alveolar epithelial cells (HPAEpiC) revealed that smoke exposure significantly reduced Let-7f-1-3p expression level in HSAEC and HPAEpiC. FOXO1 was verified as a putative regulatory target of Let-7f-1-3p. Let-7f-1-3p attenuates smoke-induced apoptosis in HSAEC and HPAEpiC by targeting FOXO1. | MicroRNA Let-7f-1-3p attenuates smoke-induced apoptosis in bronchial and alveolar epithelial cells in vitro by targeting FOXO1.
Han Z, Zhu Y, Cui Z, Guo P, Wei A, Meng Q. | 03/7/2020 |
| let-7f-5p upregulation ameliorated inflammation through modulating NLRP3. | Let-7f-5p ameliorates inflammation by targeting NLRP3 in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus.
Tan W, Gu Z, Leng J, Zou X, Chen H, Min F, Zhou W, Zhang L, Li G. | 02/15/2020 |
| In the risk study, the let-7i rs10877887 and let-7a-1/let-7f-1/let-7d rs13293512 were shown no significant association for the overall cancer risk. In the stratified analysis, the rs10877887 variant genotype was significantly associated with a decreased cancer risk in head and neck cancer. | A comprehensive evaluation for polymorphisms in let-7 family in cancer risk and prognosis: a system review and meta-analysis.
Wang BG, Jiang LY, Xu Q., Free PMC Article | 04/20/2019 |
| The expression levels of let-7f-5p, miR-5100 and miR-25-3p were significantly associated with the incidence rate of cALL, and these miRNAs might serve as promising biomarkers for cALL[Precursor Cell Lymphoblastic Leukemia-Lymphoma]. | [Association between expression of plasma miRNA and the risk of childhood acute lymphocytic leukemia].
Yuan DM, Wu SY, Huang SL, Jiang WC, Ke YB. | 04/6/2019 |
| identified a system through which TLR3 mediated immune response is regulated by C/EBPbeta and let-7f through the temporal activation of MAPK and NF-kappaB in human endocervical cells. | MAPK and NF-κB signalling pathways regulate the expression of miRNA, let-7f in human endocervical epithelial cells.
Ayyar KK, Reddy KVR. | 03/2/2019 |
| Cigarette smoke exposure is associated with reduced expression of let-7f and activation of the anti-angiogenic TGF-beta/ALK5 pathway. | Reduced expression of let-7f activates TGF-β/ALK5 pathway and leads to impaired ischaemia-induced neovascularization after cigarette smoke exposure.
Dhahri W, Dussault S, Haddad P, Turgeon J, Tremblay S, Rolland K, Desjarlais M, Cáceres-Gorriti KY, Mathieu R, Rivard A., Free PMC Article | 02/28/2019 |
| Aromatase inhibitor treatment significantly increased expression of let-7f in Ishikawa cells and endometrial stroma cells from patients with endometriosis. | Aromatase inhibitor regulates let-7 expression and let-7f-induced cell migration in endometrial cells from women with endometriosis.
Cho S, Mutlu L, Zhou Y, Taylor HS., Free PMC Article | 02/28/2019 |
| Data suggest that promoter activity/expression of miRNA let-7 gene cluster in skeletal muscle satellite cells are up-regulated in response to glucose, TNFa (tumor necrosis factor-alpha), and caffeine (but not insulin). | miRNA let-7 expression is regulated by glucose and TNF-α by a remote upstream promoter.
Katayama M, Sjögren RJ, Egan B, Krook A. | 02/28/2019 |
| Study identified hsalet7gf-1 to regulate the expression of TRPM6 in colorectal neoplasm. | Identification of key tumorigenesis‑related genes and their microRNAs in colon cancer.
Xie B, Zhao R, Bai B, Wu Y, Xu Y, Lu S, Fang Y, Wang Z, Maswikiti EP, Zhou X, Pan H, Han W. | 12/22/2018 |
| let-7f-1 is a direct target of transcription factor, C/EBPbeta in endocervical epithelial cells | Transcription factor CCAAT/enhancer-binding protein-β upregulates microRNA, let-7f-1 in human endocervical cells.
Ayyar K, Reddy KVR. | 06/16/2018 |
| miRlet7f1 is involved in the anticancer effects of lycopene and serves an important role in the inhibition of prostate cancer progression through the downregulation of AKT2. | MicroRNA-let-7f-1 is induced by lycopene and inhibits cell proliferation and triggers apoptosis in prostate cancer.
Li D, Chen L, Zhao W, Hao J, An R. | 01/14/2017 |
| Study show that Let-7f is down-regulated in glioma tissue and cell lines; its enhanced expression suppresses glioma cells proliferation, migration, and invasion via direct targeting perisotin suggesting it as an important role in glioma pathogenesis. | Let-7f Inhibits Glioma Cell Proliferation, Migration, and Invasion by Targeting Periostin.
Yan S, Han X, Xue H, Zhang P, Guo X, Li T, Guo X, Yuan G, Deng L, Li G. | 04/9/2016 |
| MiR-let-7f-1 is differentially expressed with cisplatin treatment in SPARC expressed cells. | miR-let-7f-1 regulates SPARC mediated cisplatin resistance in medulloblastoma cells.
Pannuru P, Dontula R, Khan AA, Herbert E, Ozer H, Chetty C, Lakka SS. | 09/5/2015 |