| Exploring a Drosophila Transcription Factor Interaction Network to Identify Cis-Regulatory Modules. | Exploring a Drosophila Transcription Factor Interaction Network to Identify Cis-Regulatory Modules.
Mahmud AKMF, Yang D, Stenberg P, Ioshikhes I, Nandi S. | 10/9/2021 |
| The authors propose that Osa and its target genes opa and D form an incoherent feedforward loop (FFL) and a new mechanism allowing the successive expression of temporal identities in intermediate neural progenitors. | The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop.
Abdusselamoglu MD, Eroglu E, Burkard TR, Knoblich JA., Free PMC Article | 12/21/2019 |
| Analysis of the functional relationship between SoxNeuro and Dichaete uncovers evidence for redundant and independent functions for each protein, along with unexpected examples of compensation and interdependency. | SoxNeuro orchestrates central nervous system specification and differentiation in Drosophila and is only partially redundant with Dichaete.
Ferrero E, Fischer B, Russell S., Free PMC Article | 03/26/2016 |
| Dichaete acts as a transcriptional hub, controlling multiple regulatory pathways during CNS development. | The role of Dichaete in transcriptional regulation during Drosophila embryonic development.
Aleksic J, Ferrero E, Fischer B, Shen SP, Russell S., Free PMC Article | 03/8/2014 |
| the early neurectoderm we implicate Dichaete in the lateral inhibition pathway and show that Dichaete acts to repress the proneural gene asense | Identifying targets of the Sox domain protein Dichaete in the Drosophila CNS via targeted expression of dominant negative proteins.
Shen SP, Aleksic J, Russell S., Free PMC Article | 06/29/2013 |
| These results suggest noncell autonomous functions of Dichaete in projection neuron differentiation as well as a potential role for Dichaete-expressing local interneurons | The sox gene Dichaete is expressed in local interneurons and functions in development of the Drosophila adult olfactory circuit.
Melnattur KV, Berdnik D, Rusan Z, Ferreira CJ, Nambu JR., Free PMC Article | 06/15/2013 |
| Data show that Dichaete appears to be a novel phosphorylation substrate for Pelle and may function in a Pelle-dependent signaling pathway during oogenesis. | Drosophila Pelle phosphorylates Dichaete protein and influences its subcellular distribution in developing oocytes.
Mutsuddi M, Mukherjee A, Shen B, Manley JL, Nambu JR. | 03/12/2011 |
| The expression of svb in a discreet domain is resolved at the level of SoxN and Dichaete. | The Drosophila HMG-domain proteins SoxNeuro and Dichaete direct trichome formation via the activation of shavenbaby and the restriction of Wingless pathway activity.
Overton PM, Chia W, Buescher M. | 01/21/2010 |
| Evidence for differential and redundant function of the Sox genes during CNS development in Drosophila | Evidence for differential and redundant function of the Sox genes Dichaete and SoxN during CNS development in Drosophila.
Overton PM, Meadows LA, Urban J, Russell S. | 01/21/2010 |
| Results show that expression of Dichaete protein is detected in the developing oocyte during early to mid stages of oogenesis, exhibits cytoplasmic distribution, and plays a direct post-transcriptional role in regulating RNA functions. | Maternal expression and function of the Drosophila sox gene Dichaete during oogenesis.
Mukherjee A, Melnattur KV, Zhang M, Nambu JR. | 01/21/2010 |
| Dichaete can physically interact with Ind and Vnd in the Drosophila central nervous system | Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS.
Zhao G, Boekhoff-Falk G, Wilson BA, Skeath JB., Free PMC Article | 01/21/2010 |