| KTN1 mediated unfolded protein response protects keratinocytes from ionizing radiation-induced DNA damage. | KTN1 mediated unfolded protein response protects keratinocytes from ionizing radiation-induced DNA damage.
Niu X, Shen Y, Wen Y, Mi X, Xie J, Zhang Y, Ding Z. | 05/9/2024 |
| A genetic and transcriptomic assessment of the KTN1 gene in Parkinson's disease risk. | A genetic and transcriptomic assessment of the KTN1 gene in Parkinson's disease risk.
Moore A, Crea PW, Makarious M, Bandres-Ciga S, Blauwendraat C, Diez-Fairen M., | 02/12/2024 |
| Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence. | Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence.
Luo X, Guo X, Luo X, Tan Y, Zhang P, Yang K, Xie T, Shi J, Zhang Y, Xu J, Zuo L, Li CR., Free PMC Article | 03/19/2022 |
| Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity. | Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity.
Gao L, Chen S, Hong M, Zhou W, Wang B, Qiu J, Xia J, Zhao P, Fu L, Wang J, Dai Y, Xie N, Yang Q, Huang HD, Gao X, Zou C., Free PMC Article | 03/12/2022 |
| Human microRNA-182-5p and kinectin 1: Potential biomarkers for prognosis in oral squamous cell carcinoma. | Human microRNA-182-5p and kinectin 1: Potential biomarkers for prognosis in oral squamous cell carcinoma.
Jakob M, Mattes LM, Unger K, Kueffer S, Hess J, Canis M, Schirmer M, Spiegel JL, Haubner F, Ihler F, Weiss BG, Kitz J. | 11/27/2021 |
| Associations of attention distractibility with attention deficit and with variation in the KTN1 gene. | Associations of attention distractibility with attention deficit and with variation in the KTN1 gene.
Tuvi I, Harro J, Kiive E, Vaht M, Bachmann T. | 05/22/2021 |
| Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum. | Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum.
Guadagno NA, Margiotta A, Bjørnestad SA, Haugen LH, Kjos I, Xu X, Hu X, Bakke O, Margadant F, Progida C., Free PMC Article | 03/20/2021 |
| KTN1 variants and risk for attention deficit hyperactivity disorder. | KTN1 variants and risk for attention deficit hyperactivity disorder.
Luo X, Guo X, Tan Y, Zhang Y, Garcia-Milian R, Wang Z, Shi J, Yu T, Ji J, Wang X, Xu J, Zhang H, Zuo L, Lu L, Wang K, Li CR., Free PMC Article | 02/20/2021 |
| Erbb2 interacting protein (ERBB2IP), a known target of miR-23c, was positively regulated by KTN1-AS1. | LncRNA KTN1-AS1 promotes tumor growth of hepatocellular carcinoma by targeting miR-23c/ERBB2IP axis.
Zhang L, Wang L, Wang Y, Chen T, Liu R, Yang W, Liu Q, Tu K. | 03/30/2019 |
| Significant association between rs12895072 and rs12434554 within the KTN1 gene and accelerated decline in Cognition performance in Chinese elderly male Gout population. | Potential contribution of the neurodegenerative disorders risk loci to cognitive performance in an elderly male gout population.
Han L, Jia Z, Cao C, Liu Z, Liu F, Wang L, Ren W, Sun M, Wang B, Li C, Chen L., Free PMC Article | 10/7/2017 |
| Our results show that kinectin-dependent ER distribution can be localized by chemoattractants and provide a mechanism for biased protrusion choices during chemotaxis in shallow gradients of chemoattractants. | Kinectin-dependent ER transport supports the focal complex maturation required for chemotaxis in shallow gradients.
Ng IC, Pawijit P, Teo LY, Li H, Lee SY, Yu H. | 08/12/2017 |
| Kinectin may have the ability to anchor mRNAs to the surface of the endoplasmic reticulum. | p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum.
Cui XA, Zhang H, Palazzo AF., Free PMC Article | 02/27/2013 |
| Kinectin is concentrated in the perinuclear sheets of the endoplasmic reticulum by interacting with polysomes. Kinectin may play a role in determinining the morphology of the endoplasmic reticulum. | Mechanisms determining the morphology of the peripheral ER.
Shibata Y, Shemesh T, Prinz WA, Palazzo AF, Kozlov MM, Rapoport TA., Free PMC Article | 02/27/2013 |
| The kinesin-1 deficiency weakened intercellular adhesion, despite the maintenance of adherens junctions and other desmosome components at the plasma membrane. | Desmosomal cadherins utilize distinct kinesins for assembly into desmosomes.
Nekrasova OE, Amargo EV, Smith WO, Chen J, Kreitzer GE, Green KJ., Free PMC Article | 02/18/2012 |
| The genes identified KTN1, ROCK1, and ZAK may be responsible for loss of cellular homeostasis in giant cells tumors of bone | Differentially expressed genes in giant cell tumor of bone.
Babeto E, Conceição AL, Valsechi MC, Peitl Junior P, de Campos Zuccari DA, de Lima LG, Bonilha JL, de Freitas Calmon M, Cordeiro JA, Rahal P. | 05/21/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| A large number of variations were found in many of the genes (myozenin 1, gamma-filamin, kinectin-1) in patients with limb-girdle muscular dystrophies and controls. | Candidate-gene testing for orphan limb-girdle muscular dystrophies.
Aurino S, Piluso G, Saccone V, Cacciottolo M, D'Amico F, Dionisi M, Totaro A, Belsito A, Di Vicino U, Nigro V, Aurino S, Piluso G, Saccone V, Cacciottolo M, D'Amico F, Dionisi M, Totaro A, Belsito A, Di Vicino U, Nigro V., Free PMC Articles: PMC2858943, PMC2858943 | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Candidate-gene testing for orphan limb-girdle muscular dystrophies.
Aurino S, Piluso G, Saccone V, Cacciottolo M, D'Amico F, Dionisi M, Totaro A, Belsito A, Di Vicino U, Nigro V, Aurino S, Piluso G, Saccone V, Cacciottolo M, D'Amico F, Dionisi M, Totaro A, Belsito A, Di Vicino U, Nigro V., Free PMC Articles: PMC2858943, PMC2858943 | 06/24/2009 |
| anchoring the elongation factor-1 complex onto endoplasmic reticulum via EF-1delta/kinectin interaction is important for regulating protein synthesis in eukaryotic cells | Kinectin-dependent assembly of translation elongation factor-1 complex on endoplasmic reticulum regulates protein synthesis.
Ong LL, Lin PC, Zhang X, Chia SM, Yu H. | 01/21/2010 |
| kinectin is markedly enriched at integrin-based adhesion complexes, induced by clustering integrins with fibronectin-coated beads | Integrin clustering induces kinectin accumulation.
Tran H, Pankov R, Tran SD, Hampton B, Burgess WH, Yamada KM. | 01/21/2010 |
| The data suggests that both KNT and KNTvd4(-) participate in microtubule-dependent secretion of amylin in islet beta-cells. | Kinectin participates in microtubule-dependent hormone secretion in pancreatic islet beta-cells.
Bai JZ, Mon Y, Krissansen GW. | 01/21/2010 |
| When kinesin binds with both heads to the microtubule, the neck linkers in the rear and forward heads extend forward and backward. This supports the notion that neck linker movements accompany the 'hand-over-hand' motion of the two motor domains. | Single-molecule observations of neck linker conformational changes in the kinesin motor protein.
Tomishige M, Stuurman N, Vale RD. | 01/21/2010 |
| The presence of coiled-coil domains in the ktn1/ret fusion protein (PTC8) suggests ligand-independent dimerization and thus constitutive activation of the ret tyrosine kinase domain. | Translocation t(10;14)(q11.2:q22.1) fusing the kinetin to the RET gene creates a novel rearranged form (PTC8) of the RET proto-oncogene in radiation-induced childhood papillary thyroid carcinoma.
Salassidis K, Bruch J, Zitzelsberger H, Lengfelder E, Kellerer AM, Bauchinger M. | 05/7/2001 |