| Methylation of lncSHGL promotes adipocyte differentiation by regulating miR-149/Mospd3 axis. | Methylation of lncSHGL promotes adipocyte differentiation by regulating miR-149/Mospd3 axis.
Huang X, Liu X, Lin J., | 02/1/2024 |
| MicroRNA-149 improves osteoarthritis via repression of VCAM-1 and inactivation of PI3K/AKT pathway. | MicroRNA-149 improves osteoarthritis via repression of VCAM-1 and inactivation of PI3K/AKT pathway.
Jiang Y, Zhang L, Tian H. | 03/23/2023 |
| Macrophage miR-149-5p induction is a key driver and therapeutic target for BRONJ. | Macrophage miR-149-5p induction is a key driver and therapeutic target for BRONJ.
Shen X, Zhu W, Zhang P, Fu Y, Cheng J, Liu L, Xu R, Jiang H., Free PMC Article | 09/17/2022 |
| MicroRNA-149-Mediated MAPK1/ERK2 Suppression Attenuates Hair Follicle Stem Cell Differentiation. | MicroRNA-149-Mediated MAPK1/ERK2 Suppression Attenuates Hair Follicle Stem Cell Differentiation.
Cai B, Li M, Zheng Y, Yin Y, Jin F, Li X, Dong J, Jiao X, Liu X, Zhang K, Li D, Wang J, Yin G. | 06/18/2022 |
| Astragalus polysaccharide improve the proliferation and insulin secretion of mouse pancreatic beta cells induced by high glucose and palmitic acid partially through promoting miR-136-5p and miR-149-5p expression. | Astragalus polysaccharide improve the proliferation and insulin secretion of mouse pancreatic β cells induced by high glucose and palmitic acid partially through promoting miR-136-5p and miR-149-5p expression.
Deng S, Yang L, Ma K, Bian W., Free PMC Article | 02/19/2022 |
| miRNA-149 targets PARP-2 in endometrial epithelial and stromal cells to regulate the trophoblast attachment process. | miRNA-149 targets PARP-2 in endometrial epithelial and stromal cells to regulate the trophoblast attachment process.
Soni UK, Chadchan SB, Gupta RK, Kumar V, Kumar Jha R. | 01/22/2022 |
| Enterotoxigenic Bacteroidesfragilis Promotes Intestinal Inflammation and Malignancy by Inhibiting Exosome-Packaged miR-149-3p. | Enterotoxigenic Bacteroidesfragilis Promotes Intestinal Inflammation and Malignancy by Inhibiting Exosome-Packaged miR-149-3p.
Cao Y, Wang Z, Yan Y, Ji L, He J, Xuan B, Shen C, Ma Y, Jiang S, Ma D, Tong T, Zhang X, Gao Z, Zhu X, Fang JY, Chen H, Hong J. | 01/22/2022 |
| miR-149-3p suppressed epithelial-mesenchymal transition and tumor development in acute myeloid leukemia. | miR-149-3p suppressed epithelial-mesenchymal transition and tumor development in acute myeloid leukemia.
Tian Y, Jiang Y, Dong X, Chang Y, Chi J, Chen X. | 11/22/2021 |
| The JAK inhibitor Tofacitinib inhibits structural damage in osteoarthritis by modulating JAK1/TNF-alpha/IL-6 signaling through Mir-149-5p. | The JAK inhibitor Tofacitinib inhibits structural damage in osteoarthritis by modulating JAK1/TNF-alpha/IL-6 signaling through Mir-149-5p.
Chiu YS, Bamodu OA, Fong IH, Lee WH, Lin CC, Lu CH, Yeh CT. | 08/28/2021 |
| MiR-149 attenuates endoplasmic reticulum stress-induced inflammation and apoptosis in nonalcoholic fatty liver disease by negatively targeting ATF6 pathway. | MiR-149 attenuates endoplasmic reticulum stress-induced inflammation and apoptosis in nonalcoholic fatty liver disease by negatively targeting ATF6 pathway.
Chen Z, Liu Y, Yang L, Liu P, Zhang Y, Wang X. | 05/22/2021 |
| Melatonin suppresses ischemia-induced fibrosis by regulating miR-149. | Melatonin suppresses ischemia-induced fibrosis by regulating miR-149.
Han YS, Lee JH, Lee SH. | 11/21/2020 |
| Circ_0123996 promotes cell proliferation and fibrosisin mouse mesangial cells through sponging miR-149-5p and inducing Bach1 expression. | Circ_0123996 promotes cell proliferation and fibrosisin mouse mesangial cells through sponging miR-149-5p and inducing Bach1 expression.
Wang W, Feng J, Zhou H, Li Q. | 10/10/2020 |
| Genetic deletion of miR-149 promotes liver inflammatory response and liver carcinogenesis. | miR-149* Suppresses Liver Cancer Progression by Down-Regulating Tumor Necrosis Factor Receptor 1-Associated Death Domain Protein Expression.
Feng Q, Zhang H, Nie X, Li Y, Chen WD, Wang YD. | 05/9/2020 |
| Results showed that miR-149 was upregulated, while FoxO3 was downregulated in I/R stimulated H9C2 cells. Over-expression of miR-149 inhibited cell viability and promote pyroptosis, however, down-expression of miR-149 had an opposite effect in I/R treated H9C2 cells. | MiR-149 Aggravates Pyroptosis in Myocardial Ischemia-Reperfusion Damage via Silencing FoxO3.
Lin J, Lin H, Ma C, Dong F, Hu Y, Li H., Free PMC Article | 04/25/2020 |
| Data show that miR-149-5p protected against high-glucose (HG)-induced pancreatic beta cell apoptosis partly via suppressing bcl-2-like protein 11 (BIM) expression. | miR-149-5p protects against high glucose-induced pancreatic beta cell apoptosis via targeting the BH3-only protein BIM.
Ruan D, Liu Y, Wang X, Yang D, Sun Y. | 02/29/2020 |
| the results of the current study provided validation suggesting that the downregulation of miR-149 confers protection to retinal ganglion cells (RGCs) by means of activating the PI3K/Akt signaling pathway via upregulation of betacellulin in mice with glaucoma. Evidence presented indicated the promise of miR-149 inhibition as a potential therapeutic strategy for glaucoma treatment. | Downregulation of microRNA-149 in retinal ganglion cells suppresses apoptosis through activation of the PI3K/Akt signaling pathway in mice with glaucoma.
Nie XG, Fan DS, Huang YX, He YY, Dong BL, Gao F. | 07/13/2019 |
| miR149 was able to target Dab2 and promote the cardiac differentiation of mouse MSCs in vitro, which depended upon the Wnt/betacatenin signaling pathway. | miR‑149 promotes the myocardial differentiation of mouse bone marrow stem cells by targeting Dab2.
Lu M, Xu L, Wang M, Guo T, Luo F, Su N, Yi S, Chen T. | 09/29/2018 |
| Study in mice shows that after 24 h of food deprivation, subcutaneous inguinal white fat takes on many of the morphological and molecular characteristics of visceral fat to preserve energy via miR-149-3p-mediated suppression of PRDM16. | Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16.
Ding H, Zheng S, Garcia-Ruiz D, Hou D, Wei Z, Liao Z, Li L, Zhang Y, Han X, Zen K, Zhang CY, Li J, Jiang X., Free PMC Article | 09/15/2018 |
| These data suggested that miR-149 might be a key player of immune modulator for TLR/MyD88 signaling pathway in macrophages, which may through a mechanism of negatively regulating MyD88-dependent Toll-like receptors signaling pathway. | MicroRNA-149 negatively regulates TLR-triggered inflammatory response in macrophages by targeting MyD88.
Xu G, Zhang Z, Xing Y, Wei J, Ge Z, Liu X, Zhang Y, Huang X. | 11/8/2014 |
| mitochondrial dysfunction in the skeletal muscle of obese mice may be because of, at least in part, miR-149 dysregulation | MicroRNA-149 inhibits PARP-2 and promotes mitochondrial biogenesis via SIRT-1/PGC-1α network in skeletal muscle.
Mohamed JS, Hajira A, Pardo PS, Boriek AM. | 06/14/2014 |