| Ginsenoside Rd attenuates cerebral ischemia/reperfusion injury by exerting an anti-pyroptotic effect via the miR-139-5p/FoxO1/Keap1/Nrf2 axis. | Ginsenoside Rd attenuates cerebral ischemia/reperfusion injury by exerting an anti-pyroptotic effect via the miR-139-5p/FoxO1/Keap1/Nrf2 axis.
Yao Y, Hu S, Zhang C, Zhou Q, Wang H, Yang Y, Liu C, Ding H. | 07/16/2022 |
| MicroRNA-139-5p acts as a suppressor gene for depression by targeting nuclear receptor subfamily 3, group C, member 1. | MicroRNA-139-5p acts as a suppressor gene for depression by targeting nuclear receptor subfamily 3, group C, member 1.
Su B, Cheng S, Wang L, Wang B., Free PMC Article | 05/14/2022 |
| The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis. | The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis.
Stavast CJ, van Zuijen I, Karkoulia E, Özçelik A, van Hoven-Beijen A, Leon LG, Voerman JSA, Janssen GMC, van Veelen PA, Burocziova M, Brouwer RWW, van IJcken WFJ, Maas A, Bindels EM, van der Velden VHJ, Schliehe C, Katsikis PD, Alberich-Jorda M, Erkeland SJ., Free PMC Article | 03/12/2022 |
| MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8(+) T Cell Responses. | MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8(+) T Cell Responses.
Hope JL, Zhao M, Stairiker CJ, Kiernan CH, Carey AJ, Mueller YM, van Meurs M, Brouwers-Haspels I, Otero DC, Bae EA, Faso HA, Maas A, de Looper H, Fortina PM, Rigoutsos I, Bradley LM, Erkeland SJ, Katsikis PD., Free PMC Article | 02/12/2022 |
| Dysregulated microRNA expression in IL-4 transgenic mice, an animal model of atopic dermatitis. | Dysregulated microRNA expression in IL-4 transgenic mice, an animal model of atopic dermatitis.
Bao L, Chau CS, Lei Z, Hu H, Chan AG, Amber KT, Maienschein-Cline M, Tsoukas MM. | 02/12/2022 |
| MicroRNA-139-5p inhibits inflammatory and oxidative stress responses of Salmonella-infected macrophages through modulating TRAF6. | MicroRNA-139-5p inhibits inflammatory and oxidative stress responses of Salmonella-infected macrophages through modulating TRAF6.
Xu X, Ye T, Wang Y, Pan L, Ye Y, Ding Z, Bao D. | 01/15/2022 |
| Long noncoding RNA lnc-NAP sponges mmu-miR-139-5p to modulate Nanog functions in mouse ESCs and embryos. | Long noncoding RNA lnc-NAP sponges mmu-miR-139-5p to modulate Nanog functions in mouse ESCs and embryos.
Xie D, Tong M, Xia B, Feng G, Wang L, Li A, Luo G, Wan H, Zhang Z, Zhang H, Yang YG, Zhou Q, Wang M, Wang XJ., Free PMC Article | 11/27/2021 |
| miR-139-5p promotes neovascularization in diabetic retinopathy by regulating the phosphatase and tensin homolog. | miR-139-5p promotes neovascularization in diabetic retinopathy by regulating the phosphatase and tensin homolog.
Zhang Z, Song C, Wang T, Sun L, Qin L, Ju J. | 09/25/2021 |
| Senescence Osteoblast-Derived Exosome-Mediated miR-139-5p Regulates Endothelial Cell Functions. | Senescence Osteoblast-Derived Exosome-Mediated miR-139-5p Regulates Endothelial Cell Functions.
Lu Q, Qin H, Tan H, Wei C, Yang X, He J, Liang W, Li J., Free PMC Article | 06/19/2021 |
| MicroRNA-139-5p upregulation is associated with diabetic endothelial cell dysfunction by targeting c-jun. | MicroRNA-139-5p upregulation is associated with diabetic endothelial cell dysfunction by targeting c-jun.
Luo YF, Wan XX, Zhao LL, Guo Z, Shen RT, Zeng PY, Wang LH, Yuan JJ, Yang WJ, Yue C, Mo ZH., Free PMC Article | 05/8/2021 |
| miR-139-5p protects septic mice with acute lung injury by inhibiting Toll-like receptor 4/Myeloid differentiation factor 88/Nuclear factor-&mac_kgr;B signaling pathway. | miR-139-5p protects septic mice with acute lung injury by inhibiting Toll-like receptor 4/Myeloid differentiation factor 88/Nuclear factor-&mac_kgr;B signaling pathway.
Zhang X, Liu X, Chang R, Li Y., Free PMC Article | 05/1/2021 |
| Up-regulation of miR-139-5p protects diabetic mice from liver tissue damage and oxidative stress through inhibiting Notch signaling pathway. | Up-regulation of miR-139-5p protects diabetic mice from liver tissue damage and oxidative stress through inhibiting Notch signaling pathway.
Wei H, Huang L, Wei F, Li G, Huang B, Li J, Cao C. | 01/9/2021 |
| PICK1 attenuates high glucose-induced pancreatic beta-cell death through the PI3K/Akt pathway and is negatively regulated by miR-139-5p. | PICK1 attenuates high glucose-induced pancreatic β-cell death through the PI3K/Akt pathway and is negatively regulated by miR-139-5p.
Qiu H, Ma L, Feng F. | 08/22/2020 |
| inhibition of microRNA-139-5p promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cell via targeting Wnt/beta-catenin signaling pathway by NOTCH1 | The Inhibition of MicroRNA-139-5p Promoted Osteoporosis of Bone Marrow-Derived Mesenchymal Stem Cells by Targeting Wnt/Beta-Catenin Signaling Pathway by NOTCH1.
Feng Y, Wan P, Yin L, Lou X., Free PMC Article | 04/11/2020 |
| MicroRNA-139-3p regulates osteoblast differentiation and apoptosis by targeting ELK1 and interacting with long noncoding RNA ODSM. | MicroRNA-139-3p regulates osteoblast differentiation and apoptosis by targeting ELK1 and interacting with long noncoding RNA ODSM.
Wang Y, Wang K, Hu Z, Zhou H, Zhang L, Wang H, Li G, Zhang S, Cao X, Shi F., Free PMC Article | 12/14/2019 |
| Gomafu functioned as miR-139 sponge and led to the de-repression of its target gene Foxo1, which played an important role in gluconeogenesis in hepatocytes. | Long noncoding RNA Gomafu upregulates Foxo1 expression to promote hepatic insulin resistance by sponging miR-139-5p.
Yan C, Li J, Feng S, Li Y, Tan L., Free PMC Article | 10/26/2019 |
| MiR-139-5p reduces the osteosarcoma cell migration and invasion by regulating DNMT1 and suppresses osteosarcoma tumor growth in vivo. | MiR-139-5p suppresses osteosarcoma cell growth and invasion through regulating DNMT1.
Shi YK, Guo YH. | 12/22/2018 |
| MicroRNA-139-5p suppresses myosin heavy chain I and IIa expression via inhibition of the calcineurin/NFAT signaling pathway. | MicroRNA-139-5p suppresses myosin heavy chain I and IIa expression via inhibition of the calcineurin/NFAT signaling pathway.
Xu M, Chen X, Huang Z, Chen D, Yu B, Chen H, He J, Zheng P, Luo J, Yu J, Luo Y. | 09/8/2018 |
| thi8s study shows that elevated expression of miR-139 is involved in regulating Th1/Th2 balance with acute exposure of fine particulate matter in mice | Elevated expression of miR-146, miR-139 and miR-340 involved in regulating Th1/Th2 balance with acute exposure of fine particulate matter in mice.
Hou T, Liao J, Zhang C, Sun C, Li X, Wang G. | 07/28/2018 |
| miR139-5p is a potent tumor suppressor in acute myeloid leukemia. | MiR-139-5p is a potent tumor suppressor in adult acute myeloid leukemia.
Krowiorz K, Ruschmann J, Lai C, Ngom M, Maetzig T, Martins V, Scheffold A, Schneider E, Pochert N, Miller C, Palmqvist L, Staffas A, Mulaw M, Bohl SR, Buske C, Heuser M, Kraus J, O'Neill K, Hansen CL, Petriv OI, Kestler H, Döhner H, Bullinger L, Döhner K, Humphries RK, Rouhi A, Kuchenbauer F., Free PMC Article | 03/31/2018 |
| our results identify miR-139-5p as a key regulator of cellular proliferation during early hematopoiesis and suggest that it is a potent antileukemic molecule. | MicroRNA-139-5p regulates proliferation of hematopoietic progenitors and is repressed during BCR-ABL-mediated leukemogenesis.
Choi J, Kim YK, Park K, Nah J, Yoon SS, Kim DW, Kim VN, Seong RH. | 07/29/2017 |
| Results suggest that 25-hydroxycholesterol (25-HC) induced the interaction between NFATc1 and Sp1, reducing the level of free Sp1 to inhibit microRNA miR-139-5p expression and promote osteoclastogenesis. | 25-hydroxycholesterol promotes RANKL-induced osteoclastogenesis through coordinating NFATc1 and Sp1 complex in the transcription of miR-139-5p.
Zhang L, Lv Y, Xian G, Lin Y. | 06/24/2017 |
| Findings demonstrate that miR-139 exerts a pathogenic effect in Alzheimer's disease by modulating CB2-meditated neuroinflammatory processes. | MicroRNA-139 modulates Alzheimer's-associated pathogenesis in SAMP8 mice by targeting cannabinoid receptor type 2.
Tang Y, Bao JS, Su JH, Huang W. | 03/4/2017 |
| miR-139-5p plays a crucial role in the development and progression of colitis-associated tumorigenesis. | The loss of MiR-139-5p promotes colitis-associated tumorigenesis by mediating PI3K/AKT/Wnt signaling.
Maoa R, Zou F, Yang L, Lin S, Li Y, Ma M, Yin P, Liang X, Liu J. | 09/24/2016 |
| Endothelial CXCR4 is negatively regulated by miR-139-5p, whose transcription is in turn induced by laminar flow and APLN/APLNR signalling. | MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation.
Papangeli I, Kim J, Maier I, Park S, Lee A, Kang Y, Tanaka K, Khan OF, Ju H, Kojima Y, Red-Horse K, Anderson DG, Siekmann AF, Chun HJ., Free PMC Article | 09/17/2016 |