| Association between KRAS mutation and alcohol consumption in Brazilian patients with colorectal cancer. | Association between KRAS mutation and alcohol consumption in Brazilian patients with colorectal cancer.
Gomes-Fernandes B, Trindade LM, de Castro Bastos Rodrigues M, Cardoso JPD, Lima FT, Rogerio L, de Vasconcelos Generoso S, Carneiro JG, da Silva RG, de Souza RP, De Marco L, Bastos-Rodrigues L., Free PMC Article | 11/7/2024 |
| Loss of Heterozygosity and Mutations in the RAS-ERK Pathway Genes in Tumor Cells of Various Loci in Multiple Myeloma. | Loss of Heterozygosity and Mutations in the RAS-ERK Pathway Genes in Tumor Cells of Various Loci in Multiple Myeloma.
Soloveva M, Solovev M, Risinskaya N, Nikulina E, Yakutik I, Biderman B, Obukhova T, Chabaeva Y, Kulikov S, Sudarikov A, Mendeleeva L., Free PMC Article | 11/6/2024 |
| Influence of recipient KRAS gene rs712 polymorphisms on the overall survival rate of hepatocellular carcinoma after hepatic transplantation. | Influence of recipient KRAS gene rs712 polymorphisms on the overall survival rate of hepatocellular carcinoma after hepatic transplantation.
Chu T, Zhang R, Liu X, Lin L, Li Y, Niu Z, Quan H, Zhao Y, Li Y., Free PMC Article | 11/4/2024 |
| KRAS mutation promotes the colonization of Fusobacterium nucleatum in colorectal cancer by down-regulating SERTAD4. | KRAS mutation promotes the colonization of Fusobacterium nucleatum in colorectal cancer by down-regulating SERTAD4.
Chen Y, Zheng Y, Liu S., Free PMC Article | 11/4/2024 |
| The prominent pervasive oncogenic role and tissue specific permissiveness of RAS gene mutations. | The prominent pervasive oncogenic role and tissue specific permissiveness of RAS gene mutations.
Yi M, Soppet D, McCormick F, Nissley DV., Free PMC Article | 10/31/2024 |
| PARP-1 selectively impairs KRAS-driven phenotypic and molecular features in intrahepatic cholangiocarcinoma. | PARP-1 selectively impairs KRAS-driven phenotypic and molecular features in intrahepatic cholangiocarcinoma.
Keggenhoff FL, Castven D, Becker D, Stojkovic S, Castven J, Zimpel C, Straub BK, Gerber T, Langer H, Hähnel P, Kindler T, Fahrer J, O'Rourke CJ, Ehmer U, Saborowski A, Ma L, Wang XW, Gaiser T, Matter MS, Sina C, Derer S, Lee JS, Roessler S, Kaina B, Andersen JB, Galle PR, Marquardt JU., Free PMC Article | 10/30/2024 |
| Oncogenic KRAS drives immunosuppression of colorectal cancer by impairing DDX60-mediated dsRNA accumulation and viral mimicry. | Oncogenic KRAS drives immunosuppression of colorectal cancer by impairing DDX60-mediated dsRNA accumulation and viral mimicry.
Zhou Y, Zhang Y, Li M, Ming T, Zhang C, Huang C, Li J, Li F, Li H, Zhao E, Shu F, Liu L, Pan X, Gao Y, Tian L, Song L, Huang H, Liao W. | 10/10/2024 |
| Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells. | Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells.
Park JM, Su YH, Fan CS, Chen HH, Qiu YK, Chen LL, Chen HA, Ramasamy TS, Chang JS, Huang SY, Chang WW, Lee AY, Huang TS, Kuo CC, Chiu CF., Free PMC Article | 10/9/2024 |
| The TRIM4 E3 ubiquitin ligase degrades TPL2 and is modulated by oncogenic KRAS. | The TRIM4 E3 ubiquitin ligase degrades TPL2 and is modulated by oncogenic KRAS.
Bansod S, Dodhiawala PB, Geng Y, Bulle A, Liu P, Li L, Townsend R, Grierson PM, Held JM, Adhikari H, Lim KH., Free PMC Article | 10/2/2024 |
| Prevalence of KRAS amplification in patients with metastatic cancer: Real-world next-generation sequencing analysis. | Prevalence of KRAS amplification in patients with metastatic cancer: Real-world next-generation sequencing analysis.
Choi DH, Jang HL, Lim SH, Kim ST, Hong JY, Park SH, Park JO, Kim DG, Kim KM, Lee J. | 09/25/2024 |
| Oncogenic KRAS Induces Arginine Auxotrophy and Confers a Therapeutic Vulnerability to SLC7A1 Inhibition in Non-Small Cell Lung Cancer. | Oncogenic KRAS Induces Arginine Auxotrophy and Confers a Therapeutic Vulnerability to SLC7A1 Inhibition in Non-Small Cell Lung Cancer.
Gai X, Liu Y, Lan X, Chen L, Yuan T, Xu J, Li Y, Zheng Y, Yan Y, Yang L, Fu Y, Tang S, Cao S, Dai X, Zhu H, Geng M, Ding J, Pu C, Huang M. | 09/23/2024 |
| Combined KRAS and TP53 mutation in patients with colorectal cancer enhance chemoresistance to promote postoperative recurrence and metastasis. | Combined KRAS and TP53 mutation in patients with colorectal cancer enhance chemoresistance to promote postoperative recurrence and metastasis.
Tang Y, Fan Y., Free PMC Article | 09/20/2024 |
| Association of KRAS Mutation and Gene Pathways in Colorectal Carcinoma: A Transcriptome- and Methylome-Wide Study and Potential Implications for Therapy. | Association of KRAS Mutation and Gene Pathways in Colorectal Carcinoma: A Transcriptome- and Methylome-Wide Study and Potential Implications for Therapy.
Jasmine F, Almazan A, Khamkevych Y, Bissonnette M, Ahsan H, Kibriya MG., Free PMC Article | 09/18/2024 |
| Conformations of KRAS4B Affected by Its Partner Binding and G12C Mutation: Insights from GaMD Trajectory-Image Transformation-Based Deep Learning. | Conformations of KRAS4B Affected by Its Partner Binding and G12C Mutation: Insights from GaMD Trajectory-Image Transformation-Based Deep Learning.
Chen J, Wang J, Yang W, Zhao L, Hu G. | 09/17/2024 |
| Real-World Evidence Study of Patients with KRAS-Mutated NSCLC in Finland. | Real-World Evidence Study of Patients with KRAS-Mutated NSCLC in Finland.
Anttalainen A, Pietarinen P, Tuominen S, Mattila R, Mutka A, Knuuttila A., Free PMC Article | 09/5/2024 |
| Loss of STK11 Suppresses Lipid Metabolism and Attenuates KRAS-Induced Immunogenicity in Patients with Non-Small Cell Lung Cancer. | Loss of STK11 Suppresses Lipid Metabolism and Attenuates KRAS-Induced Immunogenicity in Patients with Non-Small Cell Lung Cancer.
Principe DR, Pasquinelli MM, Nguyen RH, Munshi HG, Hulbert A, Aissa AF, Weinberg F., Free PMC Article | 09/4/2024 |
| Inhibition of ULK1/2 and KRAS[G12C] controls tumor growth in preclinical models of lung cancer. | Inhibition of ULK1/2 and KRAS(G12C) controls tumor growth in preclinical models of lung cancer.
Ghazi PC, O'Toole KT, Srinivas Boggaram S, Scherzer MT, Silvis MR, Zhang Y, Bogdan M, Smith BD, Lozano G, Flynn DL, Snyder EL, Kinsey CG, McMahon M., Free PMC Article | 09/4/2024 |
| Variation in KRAS/NRAS/BRAF-Mutation Status by Age, Sex, and Race/Ethnicity Among a Large Cohort of Patients with Metastatic Colorectal Cancer (mCRC). | Variation in KRAS/NRAS/BRAF-Mutation Status by Age, Sex, and Race/Ethnicity Among a Large Cohort of Patients with Metastatic Colorectal Cancer (mCRC).
Booker BD, Markt SC, Schumacher FR, Rose J, Cooper G, Selfridge JE, Koroukian SM. | 08/30/2024 |
| Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis. | Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis.
Moye AL, Dost AF, Ietswaart R, Sengupta S, Ya V, Aluya C, Fahey CG, Louie SM, Paschini M, Kim CF., Free PMC Article | 08/13/2024 |
| Molecular Mechanism of Phosphorylation-Mediated Impacts on the Conformation Dynamics of GTP-Bound KRAS Probed by GaMD Trajectory-Based Deep Learning. | Molecular Mechanism of Phosphorylation-Mediated Impacts on the Conformation Dynamics of GTP-Bound KRAS Probed by GaMD Trajectory-Based Deep Learning.
Chen J, Wang J, Yang W, Zhao L, Zhao J, Hu G., Free PMC Article | 08/13/2024 |
| KRAS and BRAF genetic alterations in lung cancer: A case - control study. | KRAS and BRAF genetic alterations in lung cancer: A case - control study.
Sawal HA, Shah SI, Malik SS, Mehmood S, Baig M, Rasool E, Masood N. | 08/5/2024 |
| KRAS Mutation Subtypes and Their Association with Other Driver Mutations in Oncogenic Pathways. | KRAS Mutation Subtypes and Their Association with Other Driver Mutations in Oncogenic Pathways.
Mondal K, Posa MK, Shenoy RP, Roychoudhury S., Free PMC Article | 08/1/2024 |
| Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex. | Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex.
Damianou A, Liang Z, Lassen F, Vendrell I, Vere G, Hester S, Charles PD, Pinto-Fernandez A, Santos A, Fischer R, Kessler BM., Free PMC Article | 08/1/2024 |
| KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis. | KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis.
Sigafoos AN, Tolosa EJ, Carr RM, Fernandez-Barrena MG, Almada LL, Pease DR, Hogenson TL, Raja Arul GL, Mousavi F, Sen S, Vera RE, Marks DL, Flores LF, LaRue-Nolan KC, Wu C, Bamlet WR, Vrabel AM, Sicotte H, Schenk EL, Smyrk TC, Zhang L, Rabe KG, Oberg AL, Zaphiropoulos PG, Chevet E, Graham RP, Hagen CE, di Magliano MP, Elsawa SF, Pin CL, Mao J, McWilliams RR, Fernandez-Zapico ME., Free PMC Article | 07/31/2024 |
| Endogenous oncogenic KRAS expression increases cell proliferation and motility in near-diploid hTERT RPE-1 cells. | Endogenous oncogenic KRAS expression increases cell proliferation and motility in near-diploid hTERT RPE-1 cells.
Hindul NL, Abbott LR, Adan SMD, Straatman KR, Fry AM, Hirota K, Tanaka K., Free PMC Article | 07/24/2024 |