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    ARG1 arginase 1 [ Homo sapiens (human) ]

    Gene ID: 383, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Emergence of dysfunctional neutrophils with a defect in arginase-1 release in severe COVID-19.

    Emergence of dysfunctional neutrophils with a defect in arginase-1 release in severe COVID-19.
    Dwivedi A, Ui Mhaonaigh A, Carroll M, Khosravi B, Batten I, Ballantine RS, Hendricken Phelan S, O'Doherty L, George AM, Sui J, Hawerkamp HC, Fallon PG, Noppe E, Mason S, Conlon N, Ni Cheallaigh C, Finlay CM, Little MA, Bioresource OBOTSJATTARS., Free PMC Article

    10/31/2024
    Quantitative Multiplexed Analysis of Indoleamine 2,3-Dioxygenase (IDO) and Arginase-1 (ARG1) Expression and Myeloid Cell Infiltration in Colorectal Cancer.

    Quantitative Multiplexed Analysis of Indoleamine 2,3-Dioxygenase (IDO) and Arginase-1 (ARG1) Expression and Myeloid Cell Infiltration in Colorectal Cancer.
    Elomaa H, Härkönen J, Väyrynen SA, Ahtiainen M, Ogino S, Nowak JA, Lau MC, Helminen O, Wirta EV, Seppälä TT, Böhm J, Mecklin JP, Kuopio T, Väyrynen JP.

    05/9/2024
    Arginase-induced cell death pathways and metabolic changes in cancer cells are not altered by insulin.

    Arginase-induced cell death pathways and metabolic changes in cancer cells are not altered by insulin.
    Chew HY, Cvetkovic G, Tepic S, Wells JW., Free PMC Article

    03/4/2024
    DDR2-regulated arginase activity in ovarian cancer-associated fibroblasts promotes collagen production and tumor progression.

    DDR2-regulated arginase activity in ovarian cancer-associated fibroblasts promotes collagen production and tumor progression.
    Akinjiyan FA, Ibitoye Z, Zhao P, Shriver LP, Patti GJ, Longmore GD, Fuh KC., Free PMC Article

    01/27/2024
    Arginase-1 promotes lens epithelial-to-mesenchymal transition in different models of anterior subcapsular cataract.

    Arginase-1 promotes lens epithelial-to-mesenchymal transition in different models of anterior subcapsular cataract.
    Li Q, Wang Y, Shi L, Wang Q, Yang G, Deng L, Tian Y, Hua X, Yuan X., Free PMC Article

    09/28/2023
    Arginase 1 is a key driver of immune suppression in pancreatic cancer.

    Arginase 1 is a key driver of immune suppression in pancreatic cancer.
    Menjivar RE, Nwosu ZC, Du W, Donahue KL, Hong HS, Espinoza C, Brown K, Velez-Delgado A, Yan W, Lima F, Bischoff A, Kadiyala P, Salas-Escabillas D, Crawford HC, Bednar F, Carpenter E, Zhang Y, Halbrook CJ, Lyssiotis CA, Pasca di Magliano M., Free PMC Article

    06/22/2023
    Arginase-1+ bone marrow myeloid cells are reduced in myeloproliferative neoplasms and correlate with clinical phenotype, fibrosis, and molecular driver.

    Arginase-1+ bone marrow myeloid cells are reduced in myeloproliferative neoplasms and correlate with clinical phenotype, fibrosis, and molecular driver.
    Bonometti A, Borsani O, Rumi E, Ferretti VV, Dioli C, Lucato E, Paulli M, Boveri E., Free PMC Article

    05/4/2023
    Pathophysiological correlation of arginase-1 in development of type 2 diabetes from obesity in adolescents.

    Pathophysiological correlation of arginase-1 in development of type 2 diabetes from obesity in adolescents.
    Mazrouei S, Petry SF, Sharifpanah F, Javanmard SH, Kelishadi R, Schulze PC, Franz M, Jung C.

    01/11/2023
    Expression of Inhibitory Molecules (Arginase-1, IDO, and PD-L1) by Myeloid-Derived Suppressor Cells in Multiple Myeloma Patients in Remission.

    Expression of Inhibitory Molecules (Arginase-1, IDO, and PD-L1) by Myeloid-Derived Suppressor Cells in Multiple Myeloma Patients in Remission.
    Tyrinova TV, Batorov EV, Aristova TA, Ushakova GY, Sizikova SA, Denisova VV, Ostanin AA, Chernykh ER.

    12/17/2022
    Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils.

    Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils.
    Zhang H, Zhu X, Friesen TJ, Kwak JW, Pisarenko T, Mekvanich S, Velasco MA, Randolph TW, Kargl J, Houghton AM., Free PMC Article

    11/26/2022
    ARG1 and CXCL2 are potential biomarkers target for psoriasis patients.

    ARG1 and CXCL2 are potential biomarkers target for psoriasis patients.
    Wang H, Chen W, Lie C, Zhang Y, Li J, Meng J, Zhang N., Free PMC Article

    10/15/2022
    Epithelial arginase-1 is a key mediator of age-associated delayed healing in vaginal injury.

    Epithelial arginase-1 is a key mediator of age-associated delayed healing in vaginal injury.
    Wilkinson HN, Reubinoff B, Shveiky D, Hardman MJ, Menachem-Zidon OB., Free PMC Article

    09/3/2022
    Identification of a novel homozygous intron 3 splice site (A>T) mutation in the ARG1 gene in cerebral palsy pediatric cases from Odisha, India.

    Identification of a novel homozygous intron 3 splice site (A>T) mutation in the ARG1 gene in cerebral palsy pediatric cases from Odisha, India.
    Behera CK, Rup AR, Samal S, Das B.

    06/18/2022
    Common variants in AGR1 genes contributed to the risk and traits of cirrhotic cardiomyopathy in the Han Chinese population.

    Common variants in AGR1 genes contributed to the risk and traits of cirrhotic cardiomyopathy in the Han Chinese population.
    Yu S, Sun L, Jiang J, He X, Zhou Q.

    05/14/2022
    Physical Interaction between Embryonic Stem Cell-Expressed Ras (ERas) and Arginase-1 in Quiescent Hepatic Stellate Cells.

    Physical Interaction between Embryonic Stem Cell-Expressed Ras (ERas) and Arginase-1 in Quiescent Hepatic Stellate Cells.
    Pudewell S, Lissy J, Nakhaeizadeh H, Taha MS, Akbarzadeh M, Rezaei Adariani S, Nakhaei-Rad S, Li J, Kordes C, Häussinger D, Piekorz RP, Cortese-Krott MM, Ahmadian MR., Free PMC Article

    04/16/2022
    Efficacy of expressions of Arg-1, Hep Par-1, and CK19 in the diagnosis of the primary hepatocellular carcinoma subtypes and exclusion of the metastases.

    Efficacy of expressions of Arg-1, Hep Par-1, and CK19 in the diagnosis of the primary hepatocellular carcinoma subtypes and exclusion of the metastases.
    Atta IS.

    03/26/2022
    Development of a Novel Label-Free and High-Throughput Arginase-1 Assay Using Self-Assembled Monolayer Desorption Ionization Mass Spectrometry.

    Development of a Novel Label-Free and High-Throughput Arginase-1 Assay Using Self-Assembled Monolayer Desorption Ionization Mass Spectrometry.
    Scholle MD, Gurard-Levin ZA.

    02/26/2022
    Expression dynamics of the immune mediators ARG1, TBET, CIITA, IL10 and TGFB1 in chronic myeloid leukaemia patients during the first year of imatinib therapy.

    Expression dynamics of the immune mediators ARG1, TBET, CIITA, IL10 and TGFB1 in chronic myeloid leukaemia patients during the first year of imatinib therapy.
    Toloza MJ, Bestach Y, Lincango-Yupanki M, Bordone J, Mariano R, Tarqui M, Pérez M, Aranguren PN, Enrico A, Larripa IB, Belli CB.

    02/12/2022
    Clinical effect and safety profile of pegzilarginase in patients with arginase 1 deficiency.

    Clinical effect and safety profile of pegzilarginase in patients with arginase 1 deficiency.
    Diaz GA, Schulze A, McNutt MC, Leão-Teles E, Merritt JL 2nd, Enns GM, Batzios S, Bannick A, Zori RT, Sloan LS, Potts SL, Bubb G, Quinn AG., Free PMC Article

    01/22/2022
    CD15(+) Bone Marrow-derived Cells Are Regulators of Immune Response in ARG1-producing Colorectal Cancer Cells.

    CD15(+) Bone Marrow-derived Cells Are Regulators of Immune Response in ARG1-producing Colorectal Cancer Cells.
    Miyoshi K, Sato E, Katsumata K, Fukushima G, Udo R, Nishimura E, Tago T, Kasahara K, Mazaki J, Enomoto M, Ishizaki T, Nagakawa Y, Tsuchida A.

    01/15/2022
    Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1-Dependent Myeloid Cells.

    Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1-Dependent Myeloid Cells.
    Van de Velde LA, Allen EK, Crawford JC, Wilson TL, Guy CS, Russier M, Zeitler L, Bahrami A, Finkelstein D, Pelletier S, Schultz-Cherry S, Thomas PG, Murray PJ., Free PMC Article

    01/8/2022
    Arginase II polymorphisms modify the hypotensive responses to propofol by affecting nitric oxide bioavailability.

    Arginase II polymorphisms modify the hypotensive responses to propofol by affecting nitric oxide bioavailability.
    Oliveira-Paula GH, Coeli-Lacchini FB, Ferezin LP, Ferreira GC, Pinheiro LC, Paula-Garcia WN, Garcia LV, Tanus-Santos JE, Lacchini R.

    11/22/2021
    Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action.

    Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action.
    Palte RL, Juan V, Gomez-Llorente Y, Bailly MA, Chakravarthy K, Chen X, Cipriano D, Fayad GN, Fayadat-Dilman L, Gathiaka S, Greb H, Hall B, Handa M, Hsieh M, Kofman E, Lin H, Miller JR, Nguyen N, O'Neil J, Shaheen H, Sterner E, Strickland C, Sun A, Taremi S, Scapin G., Free PMC Article

    11/13/2021
    The prognostic value of arginase-1 and glypican-3 expression levels in patients after surgical intrahepatic cholangiocarcinoma resection.

    The prognostic value of arginase-1 and glypican-3 expression levels in patients after surgical intrahepatic cholangiocarcinoma resection.
    Qiang Z, Zhang H, Jin S, Yan C, Li Z, Tao L, Yu H., Free PMC Article

    11/6/2021
    Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release.

    Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release.
    García-Navas R, Gajate C, Mollinedo F., Free PMC Article

    10/30/2021
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