| Deciphering the role of KLRB1: a novel prognostic indicator in hepatocellular carcinoma. | Deciphering the role of KLRB1: a novel prognostic indicator in hepatocellular carcinoma.
Fang S, Zhou Y., Free PMC Article | 07/12/2024 |
| KLRB1 defines an activated phenotype of CD4+ T cells and shows significant upregulation in patients with primary Sjogren's syndrome. | KLRB1 defines an activated phenotype of CD4+ T cells and shows significant upregulation in patients with primary Sjögren's syndrome.
Zhang Z, Bahabayi A, Liu D, Hasimu A, Zhang Y, Guo S, Liu R, Zhang K, Li Q, Xiong Z, Wang P, Liu C. | 06/20/2024 |
| Down-regulation of KLRB1 is associated with increased cell growth, metastasis, poor prognosis, as well as a dysfunctional immune microenvironment in LUAD. | Down-regulation of KLRB1 is associated with increased cell growth, metastasis, poor prognosis, as well as a dysfunctional immune microenvironment in LUAD.
Chen JL, Wu CY, Luo XY, Wang XY, Wang FM, Huang X, Yuan W, Guo Q., Free PMC Article | 06/3/2024 |
| A comprehensive analysis of the KLRB1 expression and its clinical implication in testicular germ cell tumors: A review. | A comprehensive analysis of the KLRB1 expression and its clinical implication in testicular germ cell tumors: A review.
Li L, Hu Y, Li X, Ju B., Free PMC Article | 04/17/2024 |
| Immune checkpoint CD161/LLT1-associated immunological landscape and diagnostic value in oral squamous cell carcinoma. | Immune checkpoint CD161/LLT1-associated immunological landscape and diagnostic value in oral squamous cell carcinoma.
Hu X, Dong Y, Xie S, Song Y, Yu C, He Y, Wang Z, Hu Q, Ni Y, Ding L., Free PMC Article | 03/20/2024 |
| Inhibiting KLRB1 expression is associated with impairing cancer immunity and leading to cancer progression and poor prognosis in breast invasive carcinoma patients. | Inhibiting KLRB1 expression is associated with impairing cancer immunity and leading to cancer progression and poor prognosis in breast invasive carcinoma patients.
He JR, Li D, Zhang QX, Liu T, Ding Y, Wu CY, Chen SS, Chen JL., Free PMC Article | 12/15/2023 |
| Eosinophilic allergic rhinitis is strongly associated with the CD45RB[lo] subset of CD161[+] Th2 cells that secretes IL-2, IL-3, IL-4, IL-5, IL-9, and IL-13. | Eosinophilic allergic rhinitis is strongly associated with the CD45RB(lo) subset of CD161(+) Th2 cells that secretes IL-2, IL-3, IL-4, IL-5, IL-9, and IL-13.
Lee WWL, Puan KJ, Lee B, Chua C, Koh SM, Yusof N, Tan KP, Luis BS, Ong J, Merid SK, Ang R, Chan XY, Hui LJ, Terenzani E, Lum J, Foo S, Zolezzi F, Yan ATS, Melen E, Yi SJ, Rotzschke O, Andiappan AK. | 10/10/2023 |
| SARS-CoV-2 infection impairs NK cell functions via activation of the LLT1-CD161 axis. | SARS-CoV-2 infection impairs NK cell functions via activation of the LLT1-CD161 axis.
Lenart M, Górecka M, Bochenek M, Barreto-Duran E, Szczepański A, Gałuszka-Bulaga A, Mazur-Panasiuk N, Węglarczyk K, Siwiec-Koźlik A, Korkosz M, Łabaj PP, Baj-Krzyworzeka M, Siedlar M, Pyrc K., Free PMC Article | 06/15/2023 |
| CD161 Characterizes an Inflamed Subset of Cytotoxic T Lymphocytes Associated with Prolonged Survival in Human Papillomavirus-Driven Oropharyngeal Cancer. | CD161 Characterizes an Inflamed Subset of Cytotoxic T Lymphocytes Associated with Prolonged Survival in Human Papillomavirus-Driven Oropharyngeal Cancer.
Wei Y, Xu T, Li C, Zhou X, Qian W, Shen C, Wang Q, Xing X, Ou X, He X, Yin H, Hu C, Wang Y, Ji Q, Su F, Lu X., Free PMC Article | 03/3/2023 |
| Immunobiology and conflicting roles of the human CD161 receptor in T cells. | Immunobiology and conflicting roles of the human CD161 receptor in T cells.
Wyrożemski Ł, Qiao SW. | 06/11/2022 |
| LLT1-CD161 Interaction in Cancer: Promises and Challenges. | LLT1-CD161 Interaction in Cancer: Promises and Challenges.
Braud VM, Meghraoui-Kheddar A, Elaldi R, Petti L, Germain C, Anjuère F., Free PMC Article | 04/2/2022 |
| Clinical characterization and immunosuppressive regulation of CD161 (KLRB1) in glioma through 916 samples. | Clinical characterization and immunosuppressive regulation of CD161 (KLRB1) in glioma through 916 samples.
Di W, Fan W, Wu F, Shi Z, Wang Z, Yu M, Zhai Y, Chang Y, Pan C, Li G, Kahlert UD, Zhang W., Free PMC Article | 02/12/2022 |
| A Pan-Cancer Analysis of CD161, a Potential New Immune Checkpoint. | A Pan-Cancer Analysis of CD161, a Potential New Immune Checkpoint.
Zhou X, Du J, Liu C, Zeng H, Chen Y, Liu L, Wu D., Free PMC Article | 10/30/2021 |
| Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis. | Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.
Mathewson ND, Ashenberg O, Tirosh I, Gritsch S, Perez EM, Marx S, Jerby-Arnon L, Chanoch-Myers R, Hara T, Richman AR, Ito Y, Pyrdol J, Friedrich M, Schumann K, Poitras MJ, Gokhale PC, Gonzalez Castro LN, Shore ME, Hebert CM, Shaw B, Cahill HL, Drummond M, Zhang W, Olawoyin O, Wakimoto H, Rozenblatt-Rosen O, Brastianos PK, Liu XS, Jones PS, Cahill DP, Frosch MP, Louis DN, Freeman GJ, Ligon KL, Marson A, Chiocca EA, Reardon DA, Regev A, Suvà ML, Wucherpfennig KW., Free PMC Article | 09/18/2021 |
| Transcription/Expression of KLRB1 Gene as A Prognostic Indicator in Human Esophageal Squamous Cell Carcinoma. | Transcription/Expression of KLRB1 Gene as A Prognostic Indicator in Human Esophageal Squamous Cell Carcinoma.
Zhang G, Liu Y, Dong F, Liu X. | 07/3/2021 |
| C-type lectin-like CD161 is not a co-signalling receptor in gluten-reactive CD4 + T cells. | C-type lectin-like CD161 is not a co-signalling receptor in gluten-reactive CD4 + T cells.
Wyrożemski Ł, Sollid LM, Qiao SW. | 06/5/2021 |
| Extracellular ATP, P2Rs, ecto-nucleotidases, adenosine, and P1Rs are basic elements of the purinergic signaling network and fundamental pillars of inflammation. | Purinergic signaling, DAMPs, and inflammation.
Di Virgilio F, Sarti AC, Coutinho-Silva R. | 08/12/2020 |
| CD161 has a role in prenatal immune suppression of IFNgamma-producing PLZF+ T cells | CD161 contributes to prenatal immune suppression of IFNγ-producing PLZF+ T cells.
Halkias J, Rackaityte E, Hillman SL, Aran D, Mendoza VF, Marshall LR, MacKenzie TC, Burt TD., Free PMC Article | 06/27/2020 |
| These novel results suggest that CD161 is often aberrantly expressed in a defined subset of T-cell prolymphocytic leukemia positive for CD8. | CD161 Is Expressed in a Subset of T-Cell Prolymphocytic Leukemia Cases and Is Useful for Disease Follow-up.
Gilles SR, Yohe SL, Linden MA, Dolan M, Hirsch B, Grzywacz B. | 03/28/2020 |
| REVIEW: Biological and Clinical Significance of Human NKRP1A/LLT1 Receptor/Ligand Interactions | Biological and Clinical Significance of Human NKRP1A/LLT1 Receptor/Ligand Interactions.
Bialoszewska A, Malejczyk J. | 09/21/2019 |
| this study shows that chronic inflammation during osteoarthritis is associated with an increased expression of CD161 during advanced stage | Chronic inflammation during osteoarthritis is associated with an increased expression of CD161 during advanced stage.
Sachdeva M, Aggarwal A, Sharma R, Randhawa A, Sahni D, Jacob J, Sharma V, Aggarwal A. | 07/13/2019 |
| CD161 expression identifies NK cells that may contribute to inflammatory disease pathogenesis and correlates with an innate responsiveness to cytokines in both T and NK cells. | CD161 Defines a Functionally Distinct Subset of Pro-Inflammatory Natural Killer Cells.
Kurioka A, Cosgrove C, Simoni Y, van Wilgenburg B, Geremia A, Björkander S, Sverremark-Ekström E, Thurnheer C, Günthard HF, Khanna N, Swiss HIV Cohort Study, Oxford IBD Cohort Investigators, Walker LJ, Arancibia-Cárcamo CV, Newell EW, Willberg CB, Klenerman P., Free PMC Article | 04/13/2019 |
| The killer cell lectin-like receptor B1 (KLRB1) 503T>C polymorphism (rs1135816) and acute rejection after liver transplantation. | The killer cell lectin-like receptor B1 (KLRB1) 503T>C polymorphism (rs1135816) and acute rejection after liver transplantation.
Thude H, Rother S, Sterneck M, Klempnauer J, Nashan B, Schwinzer R, Koch M. | 03/16/2019 |
| These results show that susceptibility of normal articular chondrocytes to lysis by NK cells is modulated by NKR-P1A/LLT1 interactions. Thus, NKR-P1A/LLT1 interaction might provide some novel target for therapeutic interventions in the course of pathological cartilage injury. | A Role of NKR-P1A (CD161) and Lectin-like Transcript 1 in Natural Cytotoxicity against Human Articular Chondrocytes.
Białoszewska A, Olkowska-Truchanowicz J, Bocian K, Osiecka-Iwan A, Czop A, Kieda C, Malejczyk J. | 09/1/2018 |
| Blocking LLT1-NKRP1A interaction will make prostate cancer cells susceptible to killing by NK cells, suggesting a therapeutic option for treatment of prostate cancer. | Overexpression of LLT1 (OCIL, CLEC2D) on prostate cancer cells inhibits NK cell-mediated killing through LLT1-NKRP1A (CD161) interaction.
Mathew SO, Chaudhary P, Powers SB, Vishwanatha JK, Mathew PA., Free PMC Article | 02/17/2018 |