| Cofilin regulates axon growth and branching of Drosophila gamma-neurons. | Cofilin regulates axon growth and branching of Drosophila γ-neurons.
Sudarsanam S, Yaniv S, Meltzer H, Schuldiner O., Free PMC Article | 08/28/2021 |
| Cofilin Loss in Drosophila Muscles Contributes to Muscle Weakness through Defective Sarcomerogenesis during Muscle Growth. | Cofilin Loss in Drosophila Muscles Contributes to Muscle Weakness through Defective Sarcomerogenesis during Muscle Growth.
Balakrishnan M, Yu SF, Chin SM, Soffar DB, Windner SE, Goode BL, Baylies MK., Free PMC Article | 05/1/2021 |
| Cofilin expression in mushroom bodies regulates actin filament dynamics and acquisition of alcohol consumption preference. | Altered Actin Filament Dynamics in the Drosophila Mushroom Bodies Lead to Fast Acquisition of Alcohol Consumption Preference.
Butts AR, Ojelade SA, Pronovost ED, Seguin A, Merrill CB, Rodan AR, Rothenfluh A., Free PMC Article | 07/4/2020 |
| Data suggest that actin-interacting protein 1 (AIP1) and twinstar protein (Drosophila cofilin gene) achieve an optimal balance between resistance to tissue tension and morphogenesis. | AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement.
Ikawa K, Sugimura K., Free PMC Article | 01/5/2019 |
| study of the structure, backbone dynamics, and biochemical activities of Twinstar; strong affinity for ADP-G-Actin and ATP-G-Actin; mild F-actin depolymerizing activity and stable interaction with F-actin | Structure, dynamics, and biochemical characterization of ADF/cofilin Twinstar from Drosophilamelanogaster.
Shukla VK, Maheshwari D, Jain A, Tripathi S, Kumar D, Arora A. | 12/22/2018 |
| Taken together, our data suggest that Tsr is required for cell survival and tissue growth by regulating JNK and Yki signaling while maintaining the epithelial integrity by controlling cell junctions. This study provides an insight into potential roles of ADF/cofilin in invasive cell migration and tumor suppression in higher animals. | Twinstar/cofilin is required for regulation of epithelial integrity and tissue growth in Drosophila.
Ko C, Kim YG, Le TP, Choi KW. | 09/2/2017 |
| Mical and cofilin, therefore, form a redox-dependent synergistic pair that promotes F-actin instability by rapidly dismantling F-actin and generating post-translationally modified actin that has altered assembly properties | F-actin dismantling through a redox-driven synergy between Mical and cofilin.
Grintsevich EE, Yesilyurt HG, Rich SK, Hung RJ, Terman JR, Reisler E., Free PMC Article | 06/10/2017 |
| Cofilin/Twinstar phosphorylation levels increase in response to impaired coenzyme a metabolism. | Cofilin/Twinstar phosphorylation levels increase in response to impaired coenzyme a metabolism.
Siudeja K, Grzeschik NA, Rana A, de Jong J, Sibon OC., Free PMC Article | 05/4/2013 |
| AIP1 enhances cofilin-mediated actin disassembly in the apical region of precluster cells to promote remodeling of adherense junctions. | AIP1 acts with cofilin to control actin dynamics during epithelial morphogenesis.
Chu D, Pan H, Wan P, Wu J, Luo J, Zhu H, Chen J. | 11/24/2012 |
| Data show that cofilin is required for F-actin turnover and lamellipodial protrusion in the border cells. | Regulation of cofilin phosphorylation and asymmetry in collective cell migration during morphogenesis.
Zhang L, Luo J, Wan P, Wu J, Laski F, Chen J. | 02/5/2011 |
| Results show that twinstar (tsr), which encodes Drosophila cofilin/ADF (actin-depolymerizing factor), is required for elongation of the retinal cell body and the morphogenesis of the rhabdomere. | Cofilin/ADF is required for retinal elongation and morphogenesis of the Drosophila rhabdomere.
Pham H, Yu H, Laski FA., Free PMC Article | 01/21/2010 |
| tsr is required for planar cell polarity patterning. | Twinstar, the Drosophila homolog of cofilin/ADF, is required for planar cell polarity patterning.
Blair A, Tomlinson A, Pham H, Gunsalus KC, Goldberg ML, Laski FA. | 01/21/2010 |
| These results indicate that changes in the extent of cofilin phosphorylation are regulated by Ssh in response to changes in the levels and/or organisation of F-actin. | Dynamic cofilin phosphorylation in the control of lamellipodial actin homeostasis.
Jovceva E, Larsen MR, Waterfield MD, Baum B, Timms JF. | 01/21/2010 |