| The role of FATP1 in lipid accumulation: a review. | The role of FATP1 in lipid accumulation: a review.
Huang J, Zhu R, Shi D. | 07/17/2021 |
| Unraveling FATP1, regulated by ER-beta, as a targeted breast cancer innovative therapy. | Unraveling FATP1, regulated by ER-β, as a targeted breast cancer innovative therapy.
Mendes C, Lopes-Coelho F, Ramos C, Martins F, Santos I, Rodrigues A, Silva F, André S, Serpa J., Free PMC Article | 10/31/2020 |
| The inhibition of Fatp1 by tumor necrosis factor alpha alleviated oleate-induced total FFA and TG accumulation in macrophages. | PPARα and PPARγ activation attenuates total free fatty acid and triglyceride accumulation in macrophages via the inhibition of Fatp1 expression.
Ye G, Gao H, Wang Z, Lin Y, Liao X, Zhang H, Chi Y, Zhu H, Dong S., Free PMC Article | 04/4/2020 |
| we have established for the first time that FATP1 is a major contributor to docosahexaenoic acid efflux from human brain capillary endothelial cells | Amyloid beta(25-35) impairs docosahexaenoic acid efflux by down-regulating fatty acid transport protein 1 (FATP1/SLC27A1) protein expression in human brain capillary endothelial cells.
Ochiai Y, Uchida Y, Tachikawa M, Couraud PO, Terasaki T. | 03/21/2020 |
| In transgenic mice, lipid droplets accumulation induced by retinal pigment cells (RPCs)-specific expression of human FATP1 was non-toxic and promoted mitochondrial energy metabolism in RPCs and non-autonomously in photoreceptor cells. | Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina.
Van Den Brink DM, Cubizolle A, Chatelain G, Davoust N, Girard V, Johansen S, Napoletano F, Dourlen P, Guillou L, Angebault-Prouteau C, Bernoud-Hubac N, Guichardant M, Brabet P, Mollereau B., Free PMC Article | 01/19/2019 |
| Neonatal phthalate ester exposure induced placental MTs, FATP1 and HFABP mRNA expression | Neonatal phthalate ester exposure induced placental MTs, FATP1 and HFABP mRNA expression in two districts of southeast China.
Li B, Xu X, Zhu Y, Cao J, Zhang Y, Huo X., Free PMC Article | 12/31/2016 |
| Several proteins that are expressed in the epidermis have been proposed to facilitate the uptake of long-chain fatty acids (LCFA) in mammalian cells, CD36, fatty acid binding protein, and FATP. [review] | Fatty acid transporters in skin development, function and disease.
Lin MH, Khnykin D., Free PMC Article | 04/19/2014 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| FATP1 inhibits 11-cis retinol formation via interaction with the visual cycle retinoid isomerase RPE65 and lecithin:retinol acyltransferase | FATP1 inhibits 11-cis retinol formation via interaction with the visual cycle retinoid isomerase RPE65 and lecithin:retinol acyltransferase.
Guignard TJ, Jin M, Pequignot MO, Li S, Chassigneux Y, Chekroud K, Guillou L, Richard E, Hamel CP, Brabet P., Free PMC Article | 07/5/2010 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Identification of type 2 diabetes-associated combination of SNPs using support vector machine.
Ban HJ, Heo JY, Oh KS, Park KJ., Free PMC Article | 06/30/2010 |
| These data reveals the localization and points to a regulatory function of FATP1 in myotube mitochondria. | FATP1 localizes to mitochondria and enhances pyruvate dehydrogenase activity in skeletal myotubes.
Guitart M, Andreu AL, García-Arumi E, Briones P, Quintana E, Gómez-Foix AM, García-Martínez C. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (5) articlesGenetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).
Campa D, Hüsing A, Chang-Claude J, Dostal L, Boeing H, Kröger J, Tjønneland A, Roswall N, Overvad K, Dahm CC, Rodríguez L, Sala N, Pérez MJ, Larrañaga N, Chirlaque MD, Ardanaz E, Khaw KT, Wareham N, Allen NE, Travis RC, Trichopoulou A, Naska A, Bamia C, Palli D, Sieri S, Tumino R, Sacerdote C, van Kranen HJ, Bas Bueno-de-Mesquita H, Stattin P, Johansson M, Chajes V, Rinaldi S, Romieu I, Siddiq A, Norat T, Riboli E, Kaaks R, Canzian F. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.
Lu Y, Dollé ME, Imholz S, van 't Slot R, Verschuren WM, Wijmenga C, Feskens EJ, Boer JM. Lack of association between certain candidate gene polymorphisms and the metabolic syndrome.
Meirhaeghe A, Cottel D, Amouyel P, Dallongeville J. A common polymorphism in the fatty acid transport protein-1 gene associated with elevated post-prandial lipaemia and alterations in LDL particle size distribution.
Gertow K, Skoglund-Andersson C, Eriksson P, Boquist S, Orth-Gomér K, Schenck-Gustafsson K, Hamsten A, Fisher RM, Gertow K, Skoglund-Andersson C, Eriksson P, Boquist S, Orth-Gomér K, Schenck-Gustafsson K, Hamsten A, Fisher RM. | 03/13/2008 |
| FATP1 stimulated transport and consumption of palmitate and oleate, which they channeled away from complete oxidation and toward TAG synthesis. | Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells.
García-Martínez C, Marotta M, Moore-Carrasco R, Guitart M, Camps M, Busquets S, Montell E, Gómez-Foix AM. | 01/21/2010 |
| exogenously supplied fatty acids are preferentially channeled by an FATP1-linked mechanism into the TG biosynthetic pathway; such internalized lipids downregulate de novo sphingomyelin and cholesterol metabolism in growing 293 cells | FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells.
Hatch GM, Smith AJ, Xu FY, Hall AM, Bernlohr DA. | 01/21/2010 |
| FATP1 might play a role in post-prandial lipid metabolism and development of cardiovascular disease. | A common polymorphism in the fatty acid transport protein-1 gene associated with elevated post-prandial lipaemia and alterations in LDL particle size distribution.
Gertow K, Skoglund-Andersson C, Eriksson P, Boquist S, Orth-Gomér K, Schenck-Gustafsson K, Hamsten A, Fisher RM, Gertow K, Skoglund-Andersson C, Eriksson P, Boquist S, Orth-Gomér K, Schenck-Gustafsson K, Hamsten A, Fisher RM. | 01/21/2010 |