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    Tbp TATA binding protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37476, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Novel Antennapedia and Ultrabithorax trimeric complexes with TBP and Exd regulate transcription.

    Novel Antennapedia and Ultrabithorax trimeric complexes with TBP and Exd regulate transcription.
    Villarreal-Puente A, Altamirano-Torres C, Jiménez-Mejía G, Hernández-Bautista C, Montalvo-Méndez R, Vázquez M, Zurita M, Reséndez-Pérez D., Free PMC Article

    07/31/2024
    Trimeric complexes of Antp-TBP with TFIIEbeta or Exd modulate transcriptional activity.

    Trimeric complexes of Antp-TBP with TFIIEβ or Exd modulate transcriptional activity.
    Jiménez-Mejía G, Montalvo-Méndez R, Hernández-Bautista C, Altamirano-Torres C, Vázquez M, Zurita M, Reséndez-Pérez D., Free PMC Article

    06/18/2022
    Expression of the core promoter factors TATA box binding protein and TATA box binding protein-related factor 2 in Drosophila germ cells and their distinct functions in germline development.

    Expression of the core promoter factors TATA box binding protein and TATA box binding protein-related factor 2 in Drosophila germ cells and their distinct functions in germline development.
    Nakamura S, Hira S, Kojima M, Kondo A, Mukai M.

    09/25/2021
    Assembly of SNAPc, Bdp1, and TBP on the U6 snRNA Gene Promoter in Drosophila melanogaster.

    Assembly of SNAPc, Bdp1, and TBP on the U6 snRNA Gene Promoter in Drosophila melanogaster.
    Kim MK, Tranvo A, Hurlburt AM, Verma N, Phan P, Luo J, Ranish J, Stumph WE., Free PMC Article

    08/29/2020
    Results indicate that a portion of Brf1 is sandwiched between Bdp1 and TBP upstream of the U6 TATA box. Furthermore, Bdp1 traverses the DNA under the N-terminal stirrup of TBP to interact with the DNA (and very likely Brf1) downstream of the TATA sequence.

    TFIIIB subunit locations on U6 gene promoter DNA mapped by site-specific protein-DNA photo-cross-linking.
    Kang JJ, Kang YS, Stumph WE.

    05/13/2017
    TFIID has two disctinct modes of transcription initiation, de novo initiation and reinitiation, as revealed by the inhibitory effect of TFIID-bound tin compounds on the de novo initiation, but not on the reinitiation.

    Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation.
    Zhang Z, Boskovic Z, Hussain MM, Hu W, Inouye C, Kim HJ, Abole AK, Doud MK, Lewis TA, Koehler AN, Schreiber SL, Tjian R., Free PMC Article

    07/2/2016
    Deactivation of TBP contributes to SCA17 pathogenesis.

    Deactivation of TBP contributes to SCA17 pathogenesis.
    Hsu TC, Wang CK, Yang CY, Lee LC, Hsieh-Li HM, Ro LS, Chen CM, Lee-Chen GJ, Su MT.

    07/25/2015
    Aptamers generated by both selections were able to bind specifically to TBP, but the two groups showed characteristics which were clearly different in terms of their capability to compete with TATA-DNA.

    Perturbation of discrete sites on a single protein domain with RNA aptamers: targeting of different sides of the TATA-binding protein (TBP).
    Hohmura KI, Shi H, Hirayoshi K.

    04/5/2014
    in fruit flies, different classes of RNA polymerase III promoters differentially utilize TBP and TRF1 for the initiation of transcription.

    Differential utilization of TATA box-binding protein (TBP) and TBP-related factor 1 (TRF1) at different classes of RNA polymerase III promoters.
    Verma N, Hung KH, Kang JJ, Barakat NH, Stumph WE., Free PMC Article

    11/30/2013
    TBP activates TATA-dependent transcription and represses DPE-dependent transcription, whereas Mot1 and NC2 block TBP function and thus repress TATA-dependent transcription and activate DPE-dependent transcription.

    TBP, Mot1, and NC2 establish a regulatory circuit that controls DPE-dependent versus TATA-dependent transcription.
    Hsu JY, Juven-Gershon T, Marr MT 2nd, Wright KJ, Tjian R, Kadonaga JT., Free PMC Article

    01/21/2010
    Tbp targets core histone transcription.

    Transcription of histone gene cluster by differential core-promoter factors.
    Isogai Y, Keles S, Prestel M, Hochheimer A, Tjian R., Free PMC Article

    01/21/2010
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