| SIAH2 suppresses c-JUN pathway by promoting the polyubiquitination and degradation of HBx in hepatocellular carcinoma. | SIAH2 suppresses c-JUN pathway by promoting the polyubiquitination and degradation of HBx in hepatocellular carcinoma.
Hu Q, Liu Z, Liu Y, Qiu J, Zhang X, Sun J, Zhang B, Shi H., Free PMC Article | 10/28/2024 |
| A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth. | A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth.
Kurlishchuk Y, Cindric Vranesic A, Jessen M, Kipping A, Ritter C, Kim K, Cramer P, von Eyss B., Free PMC Article | 10/20/2024 |
| FOXA2 rewires AP-1 for transcriptional reprogramming and lineage plasticity in prostate cancer. | FOXA2 rewires AP-1 for transcriptional reprogramming and lineage plasticity in prostate cancer.
Wang Z, Townley SL, Zhang S, Liu M, Li M, Labaf M, Patalano S, Venkataramani K, Siegfried KR, Macoska JA, Han D, Gao S, Risbridger GP, Taylor RA, Lawrence MG, He HH, Selth LA, Cai C., Free PMC Article | 10/9/2024 |
| The Role of Activator Protein-1 Complex in Diabetes-Associated Atherosclerosis: Insights From Single-Cell RNA Sequencing. | The Role of Activator Protein-1 Complex in Diabetes-Associated Atherosclerosis: Insights From Single-Cell RNA Sequencing.
Khan AW, Aziz M, Sourris KC, Lee MKS, Dai A, Watson AMD, Maxwell S, Sharma A, Zhou Y, Cooper ME, Calkin AC, Murphy AJ, Baratchi S, Jandeleit-Dahm KAM. | 10/1/2024 |
| Interferon subverts an AHR-JUN axis to promote CXCL13[+] T cells in lupus. | Interferon subverts an AHR-JUN axis to promote CXCL13(+) T cells in lupus.
Law C, Wacleche VS, Cao Y, Pillai A, Sowerby J, Hancock B, Horisberger A, Bracero S, Skidanova V, Li Z, Adejoorin I, Dillon E, Benque IJ, Nunez DP, Simmons DP, Keegan J, Chen L, Baker T, Brohawn PZ, Al-Mossawi H, Hao LY, Jones B, Rao N, Qu Y, Alves SE, Accelerating Medicines Partnership: RA/SLE Network, Jonsson AH, Shaw KS, Vleugels RA, Massarotti E, Costenbader KH, Brenner MB, Lederer JA, Hultquist JF, Choi J, Rao DA. | 07/26/2024 |
| Knockdown of BUB1B Inhibits the Proliferation, Migration, and Invasion of Colorectal Cancer by Regulating the JNK/c-Jun Signaling Pathway. | Knockdown of BUB1B Inhibits the Proliferation, Migration, and Invasion of Colorectal Cancer by Regulating the JNK/c-Jun Signaling Pathway.
Zeng Q, Zhang S, He L, Fu Q, Liao L, Chen L, Ding X. | 04/17/2024 |
| Single cell RNA-seq identifies a FOS/JUN-related monocyte signature associated with clinical response of heart failure patients with mesenchymal stem cell therapy. | Single cell RNA-seq identifies a FOS/JUN-related monocyte signature associated with clinical response of heart failure patients with mesenchymal stem cell therapy.
Yuan H, Zhang P, Xin Y, Liu Z, Gao B., Free PMC Article | 04/12/2024 |
| Inhibition of ATM promotes PD-L1 expression by activating JNK/c-Jun/TNF-alpha signaling axis in triple-negative breast cancer. | Inhibition of ATM promotes PD-L1 expression by activating JNK/c-Jun/TNF-α signaling axis in triple-negative breast cancer.
Liu C, Qian X, Yu C, Xia X, Li J, Li Y, Xie Y, Gao G, Song Y, Zhang M, Xue H, Wang X, Sun H, Liu J, Deng W, Guo X. | 03/19/2024 |
| ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation. | ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation.
Mazzeo L, Ghosh S, Di Cicco E, Isma J, Tavernari D, Samarkina A, Ostano P, Youssef MK, Simon C, Dotto GP., Free PMC Article | 02/7/2024 |
| Homeobox Protein PROX1 Expression is Negatively Regulated by Histone Deacetylase 1 and c-JUN Complex in MDA-MB-231 Human Breast Cancer Cells. | Homeobox Protein PROX1 Expression is Negatively Regulated by Histone Deacetylase 1 and c-JUN Complex in MDA-MB-231 Human Breast Cancer Cells.
Jeong M, Jung E, Oh S, Shin SY. | 01/17/2024 |
| Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer. | Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer.
Lin X, Chen JD, Wang CY, Cai Z, Zhan R, Yang C, Zhang LY, Li LY, Xiao Y, Chen MK, Wu M., Free PMC Article | 12/1/2023 |
| Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer. | Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer.
He L, Shi M, Ren S, Zhang J, Tian Y, Yang X, Liu H., Free PMC Article | 11/8/2023 |
| Thrombin-Induced COX-2 Expression and PGE2 Synthesis in Human Tracheal Smooth Muscle Cells: Role of PKCdelta/Pyk2-Dependent AP-1 Pathway Modulation. | Thrombin-Induced COX-2 Expression and PGE(2) Synthesis in Human Tracheal Smooth Muscle Cells: Role of PKCδ/Pyk2-Dependent AP-1 Pathway Modulation.
Yang CC, Lee IT, Lin YJ, Wu WB, Hsiao LD, Yang CM., Free PMC Article | 10/30/2023 |
| c-JUN-induced upregulation of LINC00174 contributes to colorectal cancer proliferation and invasion through accelerating USP21 expression. | c-JUN-induced upregulation of LINC00174 contributes to colorectal cancer proliferation and invasion through accelerating USP21 expression.
Liang W, Liu D, Wu J. | 10/25/2023 |
| LncRNA THRIL, transcriptionally activated by AP-1 and stabilized by METTL14-mediated m6A modification, accelerates LPS-evoked acute injury in alveolar epithelial cells. | LncRNA THRIL, transcriptionally activated by AP-1 and stabilized by METTL14-mediated m6A modification, accelerates LPS-evoked acute injury in alveolar epithelial cells.
Shi Q, Li Z, Dong Y, Yang G, Li M. | 09/27/2023 |
| Targeting c-Jun Is a Potential Therapy for Luminal Breast Cancer Bone Metastasis. | Targeting c-Jun Is a Potential Therapy for Luminal Breast Cancer Bone Metastasis.
Han Y, Katayama S, Futakuchi M, Nakamichi K, Wakabayashi Y, Sakamoto M, Nakayama J, Semba K. | 09/6/2023 |
| c-JUN is a barrier in hESC to cardiomyocyte transition. | c-JUN is a barrier in hESC to cardiomyocyte transition.
Zhong H, Zhang R, Li G, Huang P, Zhang Y, Zhu J, Kuang J, Hutchins AP, Qin D, Zhu P, Pei D, Li D., Free PMC Article | 08/28/2023 |
| Programmed death ligand-1 regulates angiogenesis and metastasis by participating in the c-JUN/VEGFR2 signaling axis in ovarian cancer. | Programmed death ligand-1 regulates angiogenesis and metastasis by participating in the c-JUN/VEGFR2 signaling axis in ovarian cancer.
Yang Y, Xia L, Wu Y, Zhou H, Chen X, Li H, Xu M, Qi Z, Wang Z, Sun H, Cheng X., Free PMC Article | 06/15/2023 |
| Interleukin-1ss Attenuates Expression of Augmenter of Liver Regeneration (ALR) by Regulating HNF4alpha Independent of c-Jun. | Interleukin-1ß Attenuates Expression of Augmenter of Liver Regeneration (ALR) by Regulating HNF4α Independent of c-Jun.
Nimphy J, Ibrahim S, Dayoub R, Kubitza M, Melter M, Weiss TS., Free PMC Article | 06/7/2023 |
| MAPK/AP-1 Signaling Pathway Is Involved in the Protection Mechanism of Bone Marrow Mesenchymal Stem Cells-Derived Exosomes against Ultraviolet-Induced Photoaging in Human Dermal Fibroblasts. | MAPK/AP-1 Signaling Pathway Is Involved in the Protection Mechanism of Bone Marrow Mesenchymal Stem Cells-Derived Exosomes against Ultraviolet-Induced Photoaging in Human Dermal Fibroblasts.
Yan T, Huang L, Yan Y, Zhong Y, Xie H, Wang X. | 06/1/2023 |
| JNK-JUN-NCOA4 axis contributes to chondrocyte ferroptosis and aggravates osteoarthritis via ferritinophagy. | JNK-JUN-NCOA4 axis contributes to chondrocyte ferroptosis and aggravates osteoarthritis via ferritinophagy.
Sun K, Hou L, Guo Z, Wang G, Guo J, Xu J, Zhang X, Guo F. | 05/23/2023 |
| Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity. | Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Lu Y, Tang K, Wang S, Tian Z, Fan Y, Li B, Wang M, Zhao J, Xie J. | 05/17/2023 |
| Integrative epigenetic analysis reveals AP-1 promotes activation of tumor-infiltrating regulatory T cells in HCC. | Integrative epigenetic analysis reveals AP-1 promotes activation of tumor-infiltrating regulatory T cells in HCC.
Zhuo B, Zhang Q, Xie T, Wang Y, Chen Z, Zuo D, Guo B., Free PMC Article | 03/29/2023 |
| Elevation of hsa-miR-7-5p level mediated by CtBP1-p300-AP1 complex targets ATXN1 to trigger NF-kappaB-dependent inflammation response. | Elevation of hsa-miR-7-5p level mediated by CtBP1-p300-AP1 complex targets ATXN1 to trigger NF-κB-dependent inflammation response.
Lou LQ, Zhou WQ, Song X, Chen Z. | 03/28/2023 |
| LYN kinase programs stromal fibroblasts to facilitate leukemic survival via regulation of c-JUN and THBS1. | LYN kinase programs stromal fibroblasts to facilitate leukemic survival via regulation of c-JUN and THBS1.
Vom Stein AF, Rebollido-Rios R, Lukas A, Koch M, von Lom A, Reinartz S, Bachurski D, Rose F, Bozek K, Abdallah AT, Kohlhas V, Saggau J, Zölzer R, Zhao Y, Bruns C, Bröckelmann PJ, Lohneis P, Büttner R, Häupl B, Oellerich T, Nguyen PH, Hallek M., Free PMC Article | 03/21/2023 |