| Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization. | Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization.
Yatsenko AS, Kucherenko MM, Xie Y, Urlaub H, Shcherbata HR., Free PMC Article | 01/29/2022 |
| Oriented basement membrane fibrils provide a memory for F-actin planar polarization via the Dystrophin-Dystroglycan complex during tissue elongation. | Oriented basement membrane fibrils provide a memory for F-actin planar polarization via the Dystrophin-Dystroglycan complex during tissue elongation.
Cerqueira Campos F, Dennis C, Alégot H, Fritsch C, Isabella A, Pouchin P, Bardot O, Horne-Badovinac S, Mirouse V., Free PMC Article | 10/31/2020 |
| in Drosophila the microRNA complex miR-310s acts as an executive mechanism to buffer levels of the muscular dystrophy-associated extracellular matrix receptor dystroglycan via its alternative 3'-UTR | miRNA-based buffering of the cobblestone-lissencephaly-associated extracellular matrix receptor dystroglycan via its alternative 3'-UTR.
Yatsenko AS, Marrone AK, Shcherbata HR., Free PMC Article | 12/19/2015 |
| photoreceptor(R) cell differentiation defects appear at the same stage in a deficiency line Df(2R)Dg(248) that affects Dystroglycan (DG) and the neighboring mitochondrial ribosomal gene, mRpL34; findings discussed in view of recent work implicating DG as a regulator of cell metabolism and its genetic interaction with mRpL34 | Dystroglycan and mitochondrial ribosomal protein L34 regulate differentiation in the Drosophila eye.
Zhan Y, Melian NY, Pantoja M, Haines N, Ruohola-Baker H, Bourque CW, Rao Y, Carbonetto S., Free PMC Article | 11/24/2012 |
| Nrk, mbl, capt and Cam genetically interact with dystrophin and/or dystroglycan in the process of axon path-finding in the eye. | New dystrophin/dystroglycan interactors control neuron behavior in Drosophila eye.
Marrone AK, Kucherenko MM, Rishko VM, Shcherbata HR., Free PMC Article | 07/28/2012 |
| differential splicing of Dystroglycan is developmentally regulated and tissue-specific | Differential expression of Dystroglycan-spliceforms with and without the mucin-like domain during Drosophila embryogenesis.
Schneider M, Baumgartner S. | 06/18/2011 |
| only dystroglycan, but not dystrophin deficiency causes myodegeneration induced by energetic stress suggesting that dystroglycan might be a component of the low-energy pathway and act as a transducer of energetic stress in normal and dystrophic muscles | Stress and muscular dystrophy: a genetic screen for dystroglycan and dystrophin interactors in Drosophila identifies cellular stress response components.
Kucherenko MM, Marrone AK, Rishko VM, Magliarelli Hde F, Shcherbata HR. | 05/28/2011 |
| Study finds that both WW binding sites are important for maintaining full Dg function in the establishment of oocyte polarity in Drosophila. | The conserved WW-domain binding sites in Dystroglycan C-terminus are essential but partially redundant for Dystroglycan function.
Yatsenko AS, Kucherenko MM, Pantoja M, Fischer KA, Madeoy J, Deng WM, Schneider M, Baumgartner S, Akey J, Shcherbata HR, Ruohola-Baker H., Free PMC Article | 01/21/2010 |
| reduced expression of dystroglycan induced tolerance to cold as well as preference for low temperature; sustained increase in mitochondrial oxidative metabolism caused by reduced expression of DmDG accounted for the cryophilic phenotype of the atu mutant | Changes in temperature preferences and energy homeostasis in dystroglycan mutants.
Takeuchi K, Nakano Y, Kato U, Kaneda M, Aizu M, Awano W, Yonemura S, Kiyonaka S, Mori Y, Yamamoto D, Umeda M. | 01/21/2010 |
| The synaptic role of Dystroglycan (Dg) in Drosophila, is studied. | Muscle dystroglycan organizes the postsynapse and regulates presynaptic neurotransmitter release at the Drosophila neuromuscular junction.
Bogdanik L, Framery B, Frölich A, Franco B, Mornet D, Bockaert J, Sigrist SJ, Grau Y, Parmentier ML., Free PMC Article | 01/21/2010 |
| establish a central role for Dg in maintaining integrity in Drosophila larval muscles and demonstrate the importance of glycosylation to Dg function in Drosophila | Dystroglycan and protein O-mannosyltransferases 1 and 2 are required to maintain integrity of Drosophila larval muscles.
Haines N, Seabrooke S, Stewart BA., Free PMC Article | 01/21/2010 |
| the primary function of Dystroglycan in oogenesis is to organize cellular polarity | Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila.
Deng WM, Schneider M, Frock R, Castillejo-Lopez C, Gaman EA, Baumgartner S, Ruohola-Baker H. | 01/21/2010 |
| The interaction of perlecan and dystroglycan at the basal side of the epithelium promotes basal membrane differentiation and is required for maintenance of cell polarity in the follicle-cell epithelium. | Perlecan and Dystroglycan act at the basal side of the Drosophila follicular epithelium to maintain epithelial organization.
Schneider M, Khalil AA, Poulton J, Castillejo-Lopez C, Egger-Adam D, Wodarz A, Deng WM, Baumgartner S., Free PMC Article | 01/21/2010 |
| Dystroglycan links EGF receptor-induced repression of the anterior follicle cell fate and anterior-posterior polarity formation in the oocyte | Dystroglycan down-regulation links EGF receptor signaling and anterior-posterior polarity formation in the Drosophila oocyte.
Poulton JS, Deng WM., Free PMC Article | 01/21/2010 |