| UBE2I regulates the nuclear translocation of hnRNPA2B1 by contributing to SUMO modification in osteoarthritis. | UBE2I regulates the nuclear translocation of hnRNPA2B1 by contributing to SUMO modification in osteoarthritis.
Xu H, Xu B. | 07/29/2024 |
| lnc-HC negatively regulates cholesterol metabolism within hepatocytes through physical interaction with hnRNPA2B1. By further binding to the target messenger RNA of Cyp7a1 or Abca1, the lnc-HC-hnRNPA2B1 complex decreases expressions of the two genes that are implicated in cellular cholesterol excretion. | A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism.
Lan X, Yan J, Ren J, Zhong B, Li J, Li Y, Liu L, Yi J, Sun Q, Yang X, Sun J, Meng L, Zhu W, Holmdahl R, Li D, Lu S. | 07/29/2017 |
| These results show that the distribution of hnRNP A2/B1 is regulated by BDNF. | Neuronal activity induces synaptic delivery of hnRNP A2/B1 by a BDNF-dependent mechanism in cultured hippocampal neurons.
Leal G, Afonso PM, Duarte CB., Free PMC Article | 06/20/2015 |
| data suggest that a prominent down-regulation of hnRNP-A2/B1 during hypoxia is associated with the post-transcriptional suppression of hASH1 synthesis. | Shutdown of achaete-scute homolog-1 expression by heterogeneous nuclear ribonucleoprotein (hnRNP)-A2/B1 in hypoxia.
Kasim M, Benko E, Winkelmann A, Mrowka R, Staudacher JJ, Persson PB, Scholz H, Meier JC, Fähling M., Free PMC Article | 12/20/2014 |
| We describe a molecular mechanism in which inducible interactions of noncanonical RNA motif structures with targeting factor heterogeneous nuclear ribonucleoprotein (hnRNP) A2 form the basis for activity-dependent dendritic RNA targeting. | Interactions of noncanonical motifs with hnRNP A2 promote activity-dependent RNA transport in neurons.
Muslimov IA, Tuzhilin A, Tang TH, Wong RK, Bianchi R, Tiedge H., Free PMC Article | 09/27/2014 |
| hnRNP A2/B1 is involved in the tissue-specific regulation of ENaC biosynthesis and may coordinate the response of other genes relevant for transepithelial Na(+) reabsorption by aldosterone. | Heterogeneous nuclear ribonucleoprotein A2/B1 is a tissue-specific aldosterone target gene with prominent induction in the rat distal colon.
Hernández-Díaz I, Giraldez T, Morales S, Hernandez G, Salido E, Canessa CM, Alvarez de la Rosa D. | 03/9/2013 |
| Binding to hnRNP A2 and ensuing dendritic delivery are effectively competed by RNAs with CGG triplet repeat expansions | Spatial code recognition in neuronal RNA targeting: role of RNA-hnRNP A2 interactions.
Muslimov IA, Patel MV, Rose A, Tiedge H., Free PMC Article | 10/8/2011 |
| Akt1-mediated phosphorylation is crucial for the activation and recruitment of hnRNPA2 to the enhanceosome complex. | Activation of Akt is essential for the propagation of mitochondrial respiratory stress signaling and activation of the transcriptional coactivator heterogeneous ribonucleoprotein A2.
Guha M, Fang JK, Monks R, Birnbaum MJ, Avadhani NG., Free PMC Article | 03/19/2011 |
| Over-expression of hnRNP A2/B1 is associated with non-small cell lung cancer. | Deregulated expression of hnRNP A/B proteins in human non-small cell lung cancer: parallel assessment of protein and mRNA levels in paired tumour/non-tumour tissues.
Boukakis G, Patrinou-Georgoula M, Lekarakou M, Valavanis C, Guialis A., Free PMC Article | 02/5/2011 |
| Increased expression and cytoplasmic localization of hnRNP A2/B1 is associated with the development of hepatocellular carcinoma. | Up-regulation and subcellular localization of hnRNP A2/B1 in the development of hepatocellular carcinoma.
Cui H, Wu F, Sun Y, Fan G, Wang Q., Free PMC Article | 02/5/2011 |
| Results showed that expression of hnRNP A2/B1 was significantly downregulated in cerebral cortex and hippocampus from 3 to 24 hr of reperfusion after middle cerebral artery occlusion for 120 min, but significantly upregulated at 48 hr of reperfusion. | Histochemical mapping of hnRNP A2/B1 in rat brain after ischemia-reperfusion insults.
Liu Y, Gao Y, Wu Y, Wu Y, Wang H, Zhang C., Free PMC Article | 08/23/2010 |
| RNAs encoding alpha calcium calmodulin-dependent protein kinase II, neurogranin, and activity-regulated cytoskeleton-associated protein are coassembled into the same RNA granules and targeted to dendrites by the same cis/trans-determinants. | Multiplexed dendritic targeting of alpha calcium calmodulin-dependent protein kinase II, neurogranin, and activity-regulated cytoskeleton-associated protein RNAs by the A2 pathway.
Gao Y, Tatavarty V, Korza G, Levin MK, Carson JH., Free PMC Article | 01/21/2010 |
| These results establish a link between the p53 tumor suppressor and RNA processing via hnRNPA2/B1 and RNA Helicase A. | The p53 target protein Wig-1 binds hnRNP A2/B1 and RNA Helicase A via RNA.
Prahl M, Vilborg A, Palmberg C, Jörnvall H, Asker C, Wiman KG. | 01/21/2010 |
| The hnRNP-A2 to be among the primary inducers of autoimmunity in Pristane-induced arthritis(PIA). Therefore, this Ag might play a pivotal role in the pathogenesis of PIA and possibly also human rheumatoid arthritis(RA). | The rheumatoid arthritis-associated autoantigen hnRNP-A2 (RA33) is a major stimulator of autoimmunity in rats with pristane-induced arthritis.
Hoffmann MH, Tuncel J, Skriner K, Tohidast-Akrad M, Türk B, Pinol-Roma S, Serre G, Schett G, Smolen JS, Holmdahl R, Steiner G. | 01/21/2010 |
| These results are consistent with a model where hnRNP E1 recruited to A2RE RNA granules by binding to hnRNP A2 inhibits translation of A2RE RNA during granule transport. | Heterogeneous nuclear ribonucleoprotein (hnRNP) E1 binds to hnRNP A2 and inhibits translation of A2 response element mRNAs.
Kosturko LD, Maggipinto MJ, Korza G, Lee JW, Carson JH, Barbarese E., Free PMC Article | 01/21/2010 |
| The overall level of heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) increased in oligodendrocytes as they differentiated into myelin basic protein-positive cells, and this was reflected primarily in the cytoplasmic granules. | Increased expression of the MBP mRNA binding protein HnRNP A2 during oligodendrocyte differentiation.
Maggipinto M, Rabiner C, Kidd GJ, Hawkins AJ, Smith R, Barbarese E. | 01/21/2010 |