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    Gli Gliotactin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34927, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Overexpressed Gliotactin activates BMP signaling through interfering with the Tkv-Dad association.

    Overexpressed Gliotactin activates BMP signaling through interfering with the Tkv-Dad association.
    Sharifkhodaei Z, Auld VJ.

    12/4/2021
    Interplay between Anakonda, Gliotactin, and M6 for Tricellular Junction Assembly and Anchoring of Septate Junctions in Drosophila Epithelium.

    Interplay between Anakonda, Gliotactin, and M6 for Tricellular Junction Assembly and Anchoring of Septate Junctions in Drosophila Epithelium.
    Esmangart de Bournonville T, Le Borgne R.

    09/4/2021
    Disentanglement of the neighbour cells from the midbody, and the midbody movement, are impaired in the absence of the Gliotactin (Gli) and Anakonda (Aka) TCJ proteins.

    Tricellular junction proteins promote disentanglement of daughter and neighbour cells during epithelial cytokinesis.
    Wang Z, Bosveld F, Bellaïche Y.

    12/7/2019
    Gliotactin leads to a feedback loop to control Gliotactin mRNA levels thorough Tkv protein signalling and induction of miR-184.

    The Drosophila tricellular junction protein Gliotactin regulates its own mRNA levels through BMP-mediated induction of miR-184.
    Sharifkhodaei Z, Padash-Barmchi M, Gilbert MM, Samarasekera G, Fulga TA, Van Vactor D, Auld VJ., Free PMC Article

    12/31/2016
    A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response

    A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response.
    Oh S, Kato M, Zhang C, Guo Y, Beachy PA., Free PMC Article

    05/14/2016
    Gliotactin and Discs large are co-regulated to maintain epithelial integrity.

    Gliotactin and Discs large are co-regulated to maintain epithelial integrity.
    Padash-Barmchi M, Charish K, Que J, Auld VJ.

    11/2/2013
    Gliotactin levels within the cell membrane are regulated to ensure correct protein localization and cell survival.

    Control of Gliotactin localization and levels by tyrosine phosphorylation and endocytosis is necessary for survival of polarized epithelia.
    Padash-Barmchi M, Browne K, Sturgeon K, Jusiak B, Auld VJ.

    03/19/2011
    These results suggest a target gene-selective involvement of the PAF1 complex in Hh signaling via the Parafibromin/Hyx-mediated recruitment to Gli/Ci.

    The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control.
    Mosimann C, Hausmann G, Basler K.

    01/21/2010
    The intracellular domain of gliotactin is natively unfolded.

    The intracellular domain of the Drosophila cholinesterase-like neural adhesion protein, gliotactin, is natively unfolded.
    Zeev-Ben-Mordehai T, Rydberg EH, Solomon A, Toker L, Auld VJ, Silman I, Botti S, Sussman JL.

    01/21/2010
    The apical polarization of Gli and Cora functions to stabilize and align prehairs relative to anterior-posterior cell boundaries during pupal wing development.

    Transient apical polarization of Gliotactin and Coracle is required for parallel alignment of wing hairs in Drosophila.
    Venema DR, Zeev-Ben-Mordehai T, Auld VJ.

    01/21/2010
    In Gli mutants, localization of septate junction (SJ) protein markers are disrupted. Also,SJ epithelial barrier function is lost as determined by dye permeability assays.

    Gliotactin, a novel marker of tricellular junctions, is necessary for septate junction development in Drosophila.
    Schulte J, Tepass U, Auld VJ., Free PMC Article

    01/21/2010
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