Overexpressed Gliotactin activates BMP signaling through interfering with the Tkv-Dad association. | Overexpressed Gliotactin activates BMP signaling through interfering with the Tkv-Dad association. Sharifkhodaei Z, Auld VJ. | 12/4/2021 |
Interplay between Anakonda, Gliotactin, and M6 for Tricellular Junction Assembly and Anchoring of Septate Junctions in Drosophila Epithelium. | Interplay between Anakonda, Gliotactin, and M6 for Tricellular Junction Assembly and Anchoring of Septate Junctions in Drosophila Epithelium. Esmangart de Bournonville T, Le Borgne R. | 09/4/2021 |
Disentanglement of the neighbour cells from the midbody, and the midbody movement, are impaired in the absence of the Gliotactin (Gli) and Anakonda (Aka) TCJ proteins. | Tricellular junction proteins promote disentanglement of daughter and neighbour cells during epithelial cytokinesis. Wang Z, Bosveld F, Bellaïche Y. | 12/7/2019 |
Gliotactin leads to a feedback loop to control Gliotactin mRNA levels thorough Tkv protein signalling and induction of miR-184. | The Drosophila tricellular junction protein Gliotactin regulates its own mRNA levels through BMP-mediated induction of miR-184. Sharifkhodaei Z, Padash-Barmchi M, Gilbert MM, Samarasekera G, Fulga TA, Van Vactor D, Auld VJ., Free PMC Article | 12/31/2016 |
A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response | A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response. Oh S, Kato M, Zhang C, Guo Y, Beachy PA., Free PMC Article | 05/14/2016 |
Gliotactin and Discs large are co-regulated to maintain epithelial integrity. | Gliotactin and Discs large are co-regulated to maintain epithelial integrity. Padash-Barmchi M, Charish K, Que J, Auld VJ. | 11/2/2013 |
Gliotactin levels within the cell membrane are regulated to ensure correct protein localization and cell survival. | Control of Gliotactin localization and levels by tyrosine phosphorylation and endocytosis is necessary for survival of polarized epithelia. Padash-Barmchi M, Browne K, Sturgeon K, Jusiak B, Auld VJ. | 03/19/2011 |
These results suggest a target gene-selective involvement of the PAF1 complex in Hh signaling via the Parafibromin/Hyx-mediated recruitment to Gli/Ci. | The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control. Mosimann C, Hausmann G, Basler K. | 01/21/2010 |
The intracellular domain of gliotactin is natively unfolded. | The intracellular domain of the Drosophila cholinesterase-like neural adhesion protein, gliotactin, is natively unfolded. Zeev-Ben-Mordehai T, Rydberg EH, Solomon A, Toker L, Auld VJ, Silman I, Botti S, Sussman JL. | 01/21/2010 |
The apical polarization of Gli and Cora functions to stabilize and align prehairs relative to anterior-posterior cell boundaries during pupal wing development. | Transient apical polarization of Gliotactin and Coracle is required for parallel alignment of wing hairs in Drosophila. Venema DR, Zeev-Ben-Mordehai T, Auld VJ. | 01/21/2010 |
In Gli mutants, localization of septate junction (SJ) protein markers are disrupted. Also,SJ epithelial barrier function is lost as determined by dye permeability assays. | Gliotactin, a novel marker of tricellular junctions, is necessary for septate junction development in Drosophila. Schulte J, Tepass U, Auld VJ., Free PMC Article | 01/21/2010 |