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    APOE apolipoprotein E [ Homo sapiens (human) ]

    Gene ID: 348, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Impact of work type and APOE-e4 status on cognitive functioning in older women.

    Impact of work type and APOE-e4 status on cognitive functioning in older women.
    Lee LJ, Liu SM, Tabaza R, Morin R, Bennett L, Alzheimer’s Disease Neuroimaging Initiative.

    11/4/2024
    APOE expression in papillary thyroid carcinoma: Influencing tumor progression and macrophage polarization.

    APOE expression in papillary thyroid carcinoma: Influencing tumor progression and macrophage polarization.
    Huo R, Zhao R, Li Z, Li M, Bin Y, Wang D, Xue G, Wu J, Lin X.

    11/1/2024
    APOE epsilon4-associated downregulation of the IL-7/IL-7R pathway in effector memory T cells: Implications for Alzheimer's disease.

    APOE ε4-associated downregulation of the IL-7/IL-7R pathway in effector memory T cells: Implications for Alzheimer's disease.
    Zhang YJ, Cheng Y, Tang HL, Yue Q, Cai XY, Lu ZJ, Hao YX, Dai AX, Hou T, Liu HX, Kong N, Ji XY, Lu CH, Xu SL, Huang K, Zeng X, Wen YQ, Ma WY, Guan JT, Lin Y, Zheng WB, Pan H, Wu J, Wu RH, Wei NL., Free PMC Article

    11/1/2024
    Obesity affects brain cortex gene expression in an APOE genotype and sex dependent manner.

    Obesity affects brain cortex gene expression in an APOE genotype and sex dependent manner.
    Pandit H, Jones NS, Rebeck GW.,

    10/29/2024
    APOE gene polymorphism in ischemic stroke patients from Huizhou and its correlation with blood lipids and homocysteine.

    APOE gene polymorphism in ischemic stroke patients from Huizhou and its correlation with blood lipids and homocysteine.
    Tan J, Li B, Cao J, Xie H.

    10/29/2024
    Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease.

    Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease.
    Rosenzweig N, Kleemann KL, Rust T, Carpenter M, Grucci M, Aronchik M, Brouwer N, Valenbreder I, Cooper-Hohn J, Iyer M, Krishnan RK, Sivanathan KN, Brandão W, Yahya T, Durao A, Yin Z, Chadarevian JP, Properzi MJ, Nowarski R, Davtyan H, Weiner HL, Blurton-Jones M, Yang HS, Eggen BJL, Sperling RA, Butovsky O.

    10/25/2024
    APOExBDNF Interaction and Poorer Cognitive Outcomes Among Veterans With Mild Traumatic Brain Injury: An Exploratory Study.

    APOE×BDNF Interaction and Poorer Cognitive Outcomes Among Veterans With Mild Traumatic Brain Injury: An Exploratory Study.
    Ton Loy AF, Adler JS, Merritt VC, Sorg SF, Bondi MW, Delano-Wood L.

    10/20/2024
    APOE epsilon4 carrier status modifies plasma p-tau181 concentrations in cognitively healthy super-seniors.

    APOE ε4 carrier status modifies plasma p-tau181 concentrations in cognitively healthy super-seniors.
    Cooper JG, Ghodsi M, Stukas S, Leach S, Brooks-Wilson A, Wellington CL., Free PMC Article

    10/17/2024
    Association analyses of apolipoprotein E genotypes and cognitive performance in patients with Parkinson's disease.

    Association analyses of apolipoprotein E genotypes and cognitive performance in patients with Parkinson's disease.
    Zhu SG, Chen ZL, Xiao K, Wang ZW, Lu WB, Liu RP, Huang SS, Zhu JH, Zhang X, Wang JY., Free PMC Article

    10/10/2024
    Identification of a specific APOE transcript and functional elements associated with Alzheimer's disease.

    Identification of a specific APOE transcript and functional elements associated with Alzheimer's disease.
    Chen Q, Aguirre L, Liang G, Zhao H, Dong T, Borrego F, de Rojas I, Hu Q, Reyes C, Su LY, Zhang B, Lechleiter JD, Göring HHH, De Jager PL, Kleinman JE, Hyde TM, Li PP, Ruiz A, Weinberger DR, Seshadri S, Ma L., Free PMC Article

    10/8/2024
    APOE contributes to longitudinal impulse control disorders progression in Parkinson's disease.

    APOE contributes to longitudinal impulse control disorders progression in Parkinson's disease.
    Chen L, He X, Mao L, Liu P., Free PMC Article

    10/7/2024
    The effects of APOE4 and familial Alzheimer's disease mutations on free fatty acid profiles in mouse brain are age- and sex-dependent.

    The effects of APOE4 and familial Alzheimer's disease mutations on free fatty acid profiles in mouse brain are age- and sex-dependent.
    den Hoedt S, Crivelli SM, Dorst-Lagerwerf KY, Leijten FPJ, Losen M, de Vries HE, Sijbrands EJG, Verhoeven AJM, Martinez-Martinez P, Mulder MT.

    10/4/2024
    Impaired cellular copper regulation in the presence of ApoE4.

    Impaired cellular copper regulation in the presence of ApoE4.
    Blades B, Hung YH, Belaidi AA, Volitakis I, Schultz AG, Cater MA, Cheung NS, Bush AI, Ayton S, La Fontaine S.

    10/4/2024
    Synergistic Effect between the APOE epsilon4 Allele with Genetic Variants of GSK3B and MAPT: Differential Profile between Refractory Epilepsy and Alzheimer Disease.

    Synergistic Effect between the APOE ε4 Allele with Genetic Variants of GSK3B and MAPT: Differential Profile between Refractory Epilepsy and Alzheimer Disease.
    Toral-Rios D, Pichardo-Rojas P, Ruiz-Sánchez E, Rosas-Carrasco Ó, Carvajal-García R, Gálvez-Coutiño DC, Martínez-Rodríguez NL, Rubio-Chávez AD, Alcántara-Flores M, López-Ramírez A, Martínez-Rosas AR, Ruiz-Chow ÁA, Alonso-Vanegas M, Campos-Peña V., Free PMC Article

    10/3/2024
    Functional network centrality indicates interactions between APOE4 and age across the clinical spectrum of Alzheimer's Disease.

    Functional network centrality indicates interactions between APOE4 and age across the clinical spectrum of Alzheimer's Disease.
    Fall AB, Preti MG, Eshmawey M, Kagerer SM, Van De Ville D, Unschuld PG, Alzheimer’s Disease Neuroimaging Initiative., Free PMC Article

    09/27/2024
    Effects of APOE4 on omega-3 brain metabolism across the lifespan.

    Effects of APOE4 on omega-3 brain metabolism across the lifespan.
    Ebright B, Duro MV, Chen K, Louie S, Yassine HN.,

    09/24/2024
    Protein intake and episodic memory: the moderating role of the apolipoprotein E epsilon4 status.

    Protein intake and episodic memory: the moderating role of the apolipoprotein E ε4 status.
    Keum M, Lee BC, Choe YM, Suh GH, Kim SG, Kim HS, Hwang J, Yi D, Kim JW., Free PMC Article

    09/23/2024
    The biphasic impact of apolipoprotein E epsilon4 allele on age-related hearing loss.

    The biphasic impact of apolipoprotein E ε4 allele on age-related hearing loss.
    Han JS, Yoo SG, Lee SJ, Lee HJ, Choi IY, Park KH., Free PMC Article

    09/23/2024
    Retrospective analysis of Braak stage- and APOE4 allele-dependent associations between MR spectroscopy and markers of tau and neurodegeneration in cognitively unimpaired elderly.

    Retrospective analysis of Braak stage- and APOE4 allele-dependent associations between MR spectroscopy and markers of tau and neurodegeneration in cognitively unimpaired elderly.
    Chen AM, Gajdošík M, Ahmed W, Ahn S, Babb JS, Blessing EM, Boutajangout A, de Leon MJ, Debure L, Gaggi N, Gajdošík M, George A, Ghuman M, Glodzik L, Harvey P, Juchem C, Marsh K, Peralta R, Rusinek H, Sheriff S, Vedvyas A, Wisniewski T, Zheng H, Osorio R, Kirov II., Free PMC Article

    09/19/2024
    Implication of Apolipoprotein E gene variants in pediatric-onset multiple sclerosis: Possible association with disease susceptibility and its clinical characteristics, in a Hellenic cohort.

    Implication of Apolipoprotein E gene variants in pediatric-onset multiple sclerosis: Possible association with disease susceptibility and its clinical characteristics, in a Hellenic cohort.
    Skarlis C, Markoglou N, Artemiadis A, Gontika M, Koutsis G, Chrousos G, Anagnostouli M.

    09/19/2024
    Apolipoprotein E E3/E4 genotype is associated with an increased risk of coronary atherosclerosis in patients with hypertension.

    Apolipoprotein E E3/E4 genotype is associated with an increased risk of coronary atherosclerosis in patients with hypertension.
    Wei G, Li B, Wang H, Chen L, Chen W, Chen K, Wang W, Wang S, Zeng H, Liu Y, Zeng Y, Rao H., Free PMC Article

    09/12/2024
    Association of APOE genotype and cerebrospinal fluid Abeta and tau biomarkers with cognitive and motor phenotype in amyotrophic lateral sclerosis.

    Association of APOE genotype and cerebrospinal fluid Aβ and tau biomarkers with cognitive and motor phenotype in amyotrophic lateral sclerosis.
    Maranzano A, Verde F, Dubini A, Torre S, Colombo E, Doretti A, Gentile F, Manini A, Milone I, Brusati A, Peverelli S, Santangelo S, Spinelli EG, Torresani E, Gentilini D, Messina S, Morelli C, Poletti B, Agosta F, Ratti A, Filippi M, Silani V, Ticozzi N., Free PMC Article

    09/11/2024
    Role of nerve growth factor on cognitive impairment in patients with Alzheimer's disease carrying apolipoprotein E epsilon4.

    Role of nerve growth factor on cognitive impairment in patients with Alzheimer's disease carrying apolipoprotein E ε4.
    He M, Liu Z, Lian T, Guo P, Zhang W, Huang Y, Zhang Y, Liu G, Zhang W, Li J, Guan H, Zhang W, Luo D, Qi J, Yue H, Wang X, Zhang W., Free PMC Article

    09/4/2024
    Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis.

    Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis.
    Whitacre BE, Howles P, Street S, Morris J, Swertfeger D, Davidson WS., Free PMC Article

    08/27/2024
    Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain Age: A Longitudinal Cohort Study.

    Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain Age: A Longitudinal Cohort Study.
    Subramaniapillai S, Schindler LS, Redmond P, Bastin ME, Wardlaw JM, Valdés Hernández M, Maniega SM, Aribisala B, Westlye LT, Coath W, Groves J, Cash DM, Barnes J, James SN, Sudre CH, Barkhof F, Richards M, Corley J, Russ TC, Cox SR, Schott JM, Cole JH, de Lange AG., Free PMC Article

    08/26/2024
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