| Lactylated Apolipoprotein C-II Induces Immunotherapy Resistance by Promoting Extracellular Lipolysis. | Lactylated Apolipoprotein C-II Induces Immunotherapy Resistance by Promoting Extracellular Lipolysis.
Chen J, Zhao D, Wang Y, Liu M, Zhang Y, Feng T, Xiao C, Song H, Miao R, Xu L, Chen H, Qiu X, Xu Y, Xu J, Cui Z, Wang W, Quan Y, Zhu Y, Huang C, Zheng SG, Zhao JY, Zhu T, Sun L, Fan G., Free PMC Article | 10/22/2024 |
| Sequence Variant Analysis of the APOCII Locus among an Arab Cohort. | Sequence Variant Analysis of the APOCII Locus among an Arab Cohort.
Al-Bustan SA, Alrashid MH, Al-Serri AE, Annice BG, Bahbahani HM., Free PMC Article | 11/28/2023 |
| Inverse association between apolipoprotein C-II and cardiovascular mortality: role of lipoprotein lipase activity modulation. | Inverse association between apolipoprotein C-II and cardiovascular mortality: role of lipoprotein lipase activity modulation.
Silbernagel G, Chen YQ, Rief M, Kleber ME, Hoffmann MM, Stojakovic T, Stang A, Sarzynski MA, Bouchard C, März W, Qian YW, Scharnagl H, Konrad RJ. | 07/4/2023 |
| Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase. | Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase.
Kumari A, Grønnemose AL, Kristensen KK, Winther AL, Young SG, Jørgensen TJD, Ploug M., Free PMC Article | 04/26/2023 |
| ScRNA-seq expression of IFI27 and APOC2 identifies four alveolar macrophage superclusters in healthy BALF. | ScRNA-seq expression of IFI27 and APOC2 identifies four alveolar macrophage superclusters in healthy BALF.
Li X, Kolling FW, Aridgides D, Mellinger D, Ashare A, Jakubzick CV., Free PMC Article | 07/23/2022 |
| Apolipoprotein C2 - CD36 Promotes Leukemia Growth and Presents a Targetable Axis in Acute Myeloid Leukemia. | Apolipoprotein C2 - CD36 Promotes Leukemia Growth and Presents a Targetable Axis in Acute Myeloid Leukemia.
Zhang T, Yang J, Vaikari VP, Beckford JS, Wu S, Akhtari M, Alachkar H., Free PMC Article | 03/26/2022 |
| Association of the lipoprotein lipase and Apolipoprotein C-II gene polymorphisms with risk of dyslipidemia in smokers and non-smokers male. | Association of the lipoprotein lipase and Apolipoprotein C-II gene polymorphisms with risk of dyslipidemia in smokers and non-smokers male.
Al-Samawi RI, Smaism MF., Free PMC Article | 03/5/2022 |
| Apolipoprotein C-II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway. | Apolipoprotein C-II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway.
Wang C, Yang Z, Xu E, Shen X, Wang X, Li Z, Yu H, Chen K, Hu Q, Xia X, Liu S, Guan W., Free PMC Article | 02/19/2022 |
| Deregulation of apolipoprotein C2 gene in cancer: A potential metabolic vulnerability. | Deregulation of apolipoprotein C2 gene in cancer: A potential metabolic vulnerability.
Liu Y, Meng Y, Zhang T, Alachkar H., Free PMC Article | 02/12/2022 |
| Plasma apolipopotein C-2 elevation is associated with Takayasu arteritis. | Plasma apolipopotein C-2 elevation is associated with Takayasu arteritis.
Tamura N, Maejima Y, Shiheido-Watanabe Y, Nakagama S, Isobe M, Sasano T., Free PMC Article | 12/25/2021 |
| Apolipoprotein C-II and C-III preferably transfer to both high-density lipoprotein (HDL)2 and the larger HDL3 from very low-density lipoprotein (VLDL). | Apolipoprotein C-II and C-III preferably transfer to both high-density lipoprotein (HDL)2 and the larger HDL3 from very low-density lipoprotein (VLDL).
Yamazaki A, Ohkawa R, Yamagata Y, Horiuchi Y, Lai SJ, Kameda T, Ichimura N, Tohda S, Tozuka M. | 09/4/2021 |
| Regulation of lipoprotein lipase-mediated lipolysis of triglycerides. | Regulation of lipoprotein lipase-mediated lipolysis of triglycerides.
Basu D, Goldberg IJ., Free PMC Article | 06/19/2021 |
| Apolipoprotein C-II: the re-emergence of a forgotten factor. | Apolipoprotein C-II: the re-emergence of a forgotten factor.
Wolska A, Reimund M, Remaley AT. | 06/19/2021 |
| Successful management of acute pancreatitis due to apolipoprotein C-II deficiency in a 37-day-old infant. | Successful management of acute pancreatitis due to apolipoprotein C-II deficiency in a 37-day-old infant.
Yıldız Y, Uysal Yazıcı M, Çınar HG, Özbay Hoşnut F, Kurt Çolak F, Kılıç M. | 04/13/2021 |
| miR-4510 acts as a tumor suppressor in gastrointestinal stromal tumor by targeting APOC2. | miR-4510 acts as a tumor suppressor in gastrointestinal stromal tumor by targeting APOC2.
Chen Y, Qin C, Cui X, Geng W, Xian G, Wang Z. | 03/13/2021 |
| Blood miR-1275 levels were negatively associated with the occurrence of Ischemic stroke (IS), and miR-1275 might exert an athero-protective role against the development of IS by targeting ApoC2 and blocking the formation of macrophage foam cells. | Blood miR-1275 is associated with risk of ischemic stroke and inhibits macrophage foam cell formation by targeting ApoC2 gene.
Li L, Xu W, Fu X, Huang Y, Wen Y, Xu Q, He X, Wang K, Huang S, Lv Z. | 02/29/2020 |
| A case of patient with hereditary systemic amyloidosis caused by K19T apolipoprotein C-II variant is described. | Hereditary systemic amyloidosis caused by K19T apolipoprotein C-II variant.
Liapis K, Panagopoulou P, Charitaki E, Rowczenio D, Gilbertson J, Papathoma A, Kostopoulou M, Dimopoulos MA, Gillmore JD, Kastritis E. | 08/31/2019 |
| Reduced serum levels apolipoprotein A2 and apolipoprotein C2 were significantly associated with the presence of aneurysm wall enhancement in MRI angiography. | Decreased Antiatherogenic Protein Levels are Associated with Aneurysm Structure Alterations in MR Vessel Wall Imaging.
Ishii D, Matsushige T, Sakamoto S, Shimonaga K, Akiyama Y, Okazaki T, Oshita J, Kurisu K. | 08/17/2019 |
| The effect of apolipoprotein C2 K30D-D69K mutations on rod-like apolipoprotein C2 fibril formation. | Polymorphism in disease-related apolipoprotein C-II amyloid fibrils: a structural model for rod-like fibrils.
Zlatic CO, Mao Y, Todorova N, Mok YF, Howlett GJ, Yarovsky I, Gooley PR, Griffin MDW. | 06/8/2019 |
| Results from this exploratory analysis suggest that regulatory element methylation levels within the larger TOMM40-APOE-APOC2 gene region correlate with AD-related biomarkers and TOMM40 or APOE gene expression in AD. | DNA methylation of TOMM40-APOE-APOC2 in Alzheimer's disease.
Shao Y, Shaw M, Todd K, Khrestian M, D'Aleo G, Barnard PJ, Zahratka J, Pillai J, Yu CE, Keene CD, Leverenz JB, Bekris LM., Free PMC Article | 09/8/2018 |
| Triglyceride-raising variant alleles of the APOC2 encoding apo C-II, associated with clinical Cardiovascular endpoints. | Genetics of Triglycerides and the Risk of Atherosclerosis.
Dron JS, Hegele RA., Free PMC Article | 01/13/2018 |
| The results demonstrate the important role of both intra- and inter-subunit charge interactions in stabilizing apoC-II amyloid fibrils, a process that may be a key factor in determining the general ability of proteins to form amyloid fibrils. | Intra- and Intersubunit Ion-Pair Interactions Determine the Ability of Apolipoprotein C-II Mutants To Form Hybrid Amyloid Fibrils.
Todorova N, Zlatic CO, Mao Y, Yarovsky I, Howlett GJ, Gooley PR, Griffin MD. | 06/3/2017 |
| The results highlight the importance of charge-pair interactions within the apoC-II fibril core | Hydrogen/Deuterium Exchange and Molecular Dynamics Analysis of Amyloid Fibrils Formed by a D69K Charge-Pair Mutant of Human Apolipoprotein C-II.
Mao Y, Zlatic CO, Griffin MD, Howlett GJ, Todorova N, Yarovsky I, Gooley PR. | 10/24/2015 |
| Conformational rearrangement of apoC-II at lipoprotein surfaces promotes interaction with LPL. | A Pressure-dependent Model for the Regulation of Lipoprotein Lipase by Apolipoprotein C-II.
Meyers NL, Larsson M, Olivecrona G, Small DM., Free PMC Article | 10/17/2015 |
| Large deletion in APOC2 caused by Alu-Alu homologous recombination is associated with with apolipoprotein C-II deficiency. | Apolipoprotein C-II Tuzla: a novel large deletion in APOC2 caused by Alu-Alu homologous recombination in an infant with apolipoprotein C-II deficiency.
Okubo M, Toromanovic A, Ebara T, Murase T. | 08/1/2015 |