| The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood-brain barrier formation and maturation. | The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood-brain barrier formation and maturation.
Li X, Fetter R, Schwabe T, Jung C, Liu L, Steller H, Gaul U., Free PMC Article | 10/16/2021 |
| The authors show that PKA phosphorylates Meng Po and that both proteins synergize in a feedforward loop to control CREBB levels and long-term memory. | A kinase-dependent feedforward loop affects CREBB stability and long term memory formation.
Lee PT, Lin G, Lin WW, Diao F, White BH, Bellen HJ., Free PMC Article | 07/20/2019 |
| Early-onset sleep defects in mutated HTT Drosophila models of Huntington's disease reflect alterations of PKA/CREB signaling. | Early-onset sleep defects in Drosophila models of Huntington's disease reflect alterations of PKA/CREB signaling.
Gonzales ED, Tanenhaus AK, Zhang J, Chaffee RP, Yin JC., Free PMC Article | 12/17/2016 |
| Hedgehog signalling activation causes PKA to switch its substrates from Ci to Smo within the Hh signalling complex. | Switch of PKA substrates from Cubitus interruptus to Smoothened in the Hedgehog signalosome complex.
Ranieri N, Thérond PP, Ruel L. | 07/25/2015 |
| tightly controlled dose-dependent intra-neuronal PKA activity levels are critical in determining the dendritic arbor complexity, one of the possible ways being through the regulation of organelle distribution. | Developmental shaping of dendritic arbors in Drosophila relies on tightly regulated intra-neuronal activity of protein kinase A (PKA).
Copf T. | 11/29/2014 |
| Alpha- NAC is a substrate of PKA following Parathyroid Hormone signaling. | The PTH-Gαs-protein kinase A cascade controls αNAC localization to regulate bone mass.
Pellicelli M, Miller JA, Arabian A, Gauthier C, Akhouayri O, Wu JY, Kronenberg HM, St-Arnaud R., Free PMC Article | 06/7/2014 |
| that manipulations that increase cAMP/PKA signaling in adipokinetic hormone (AKH)-producing cells at the base of the neuroendocrine ring gland restore the dNf1 growth deficiency. | Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency.
Walker JA, Gouzi JY, Long JB, Huang S, Maher RC, Xia H, Khalil K, Ray A, Van Vactor D, Bernards R, Bernards A., Free PMC Article | 05/17/2014 |
| Acute expression of protein kinase A inhibitory peptide in aged animals is sufficient to reverse age-related memory impairment in wild-type animals. | Acute inhibition of PKA activity at old ages ameliorates age-related memory impairment in Drosophila.
Yamazaki D, Horiuchi J, Miyashita T, Saitoe M., Free PMC Article | 01/1/2011 |
| Two-dimensional gel electrophoresis, (32)P labelling and immunodetection show that "in vitro" PKA phosphorylates the serine in the C-terminus of the NDUFS4 subunit in isolated bovine complex I. | Phosphorylation pattern of the NDUFS4 subunit of complex I of the mammalian respiratory chain.
De Rasmo D, Palmisano G, Scacco S, Technikova-Dobrova Z, Panelli D, Cocco T, Sardanelli AM, Gnoni A, Micelli L, Trani A, Di Luccia A, Papa S. | 11/27/2010 |
| We found that decreased PKA activity in neurons rendered flies insensitive to the wake-promoting effects of octopamine. | Octopamine regulates sleep in drosophila through protein kinase A-dependent mechanisms.
Crocker A, Sehgal A., Free PMC Article | 01/21/2010 |
| Its signaling underlies age-related memory impairment.(review) | [cAMP/PKA signaling underlies age-related memory impairment].
Yamazaki D, Saitoe M. | 01/21/2010 |