| Two Cases of Recessive Intellectual Disability Caused by NDST1 and METTL23 Variants. | Two Cases of Recessive Intellectual Disability Caused by NDST1 and METTL23 Variants.
Khan A, Miao Z, Umair M, Ullah A, Alshabeeb MA, Bilal M, Ahmad F, Rappold GA, Ansar M, Carapito R., Free PMC Article | 04/3/2021 |
| MiRNA-191 functions as an oncogene in primary glioblastoma by directly targeting NDST1. | MiRNA-191 functions as an oncogene in primary glioblastoma by directly targeting NDST1.
Xue J, Yang M, Hua LH, Wang ZP. | 10/3/2020 |
| Compound heterozygous mutations in NDST1 were identified, in the heparan sulfate N deacetylatase domain of one allele and the sulfotransferase domain of the other allele. This report expands the phenotypic spectrum of Ndst1 deficiency in humans. | A girl with developmental delay, ataxia, cranial nerve palsies, severe respiratory problems in infancy-Expanding NDST1 syndrome.
Armstrong L, Tarailo-Graovac M, Sinclair G, Seath KI, Wasserman WW, Ross CJ, van Karnebeek CD. | 10/21/2017 |
| Among the genes enriched in this screening, the authors found that TM9SF2 is critical for N-sulfation of heparan sulfate and therefore for chikungunya virus infection because it is involved in the proper localization and stability of NDST1. | Genome-Wide Screening Uncovers the Significance of N-Sulfation of Heparan Sulfate as a Host Cell Factor for Chikungunya Virus Infection.
Tanaka A, Tumkosit U, Nakamura S, Motooka D, Kishishita N, Priengprom T, Sa-Ngasang A, Kinoshita T, Takeda N, Maeda Y., Free PMC Article | 07/15/2017 |
| Our data confirm NDST1 mutations as a cause of autosomal recessive intellectual disability with a distinctive phenotype, and support an important function of NDST1 in human development. | NDST1 missense mutations in autosomal recessive intellectual disability.
Reuter MS, Musante L, Hu H, Diederich S, Sticht H, Ekici AB, Uebe S, Wienker TF, Bartsch O, Zechner U, Oppitz C, Keleman K, Jamra RA, Najmabadi H, Schweiger S, Reis A, Kahrizi K. | 05/21/2016 |
| demonstrate the essential role of domain cooperation within NDST-1 in producing HS with specific domain structures | Role of Deacetylase Activity of N-Deacetylase/N-Sulfotransferase 1 in Forming N-Sulfated Domain in Heparan Sulfate.
Dou W, Xu Y, Pagadala V, Pedersen LC, Liu J., Free PMC Article | 12/12/2015 |
| Upregulation of NDST1 is associated with chemoresistance in breast cancer. | Methylation-regulated miR-149 modulates chemoresistance by targeting GlcNAc N-deacetylase/N-sulfotransferase-1 in human breast cancer.
He DX, Gu XT, Li YR, Jiang L, Jin J, Ma X. | 12/20/2014 |
| These findings establish NDST1 as a target of miR-24 and demonstrate how such NDST1 suppression in endothelial cells results in reduced responsiveness to VEGFA | MicroRNA-24 suppression of N-deacetylase/N-sulfotransferase-1 (NDST1) reduces endothelial cell responsiveness to vascular endothelial growth factor A (VEGFA).
Kasza Z, Fredlund Fuchs P, Tamm C, Eriksson AS, O'Callaghan P, Heindryckx F, Spillmann D, Larsson E, Le Jan S, Eriksson I, Gerwins P, Kjellén L, Kreuger J., Free PMC Article | 02/8/2014 |
| MicroRNA-191 targets N-deacetylase/N-sulfotransferase 1 and promotes cell growth in human gastric carcinoma cell line MGC803 | MicroRNA-191 targets N-deacetylase/N-sulfotransferase 1 and promotes cell growth in human gastric carcinoma cell line MGC803.
Shi X, Su S, Long J, Mei B, Chen Y. | 02/25/2012 |
| Inhibitory peptides of the sulfotransferase domain of the heparan sulfate enzyme, N-deacetylase-N-sulfotransferase-1. | Inhibitory peptides of the sulfotransferase domain of the heparan sulfate enzyme, N-deacetylase-N-sulfotransferase-1.
Gesteira TF, Coulson-Thomas VJ, Taunay-Rodrigues A, Oliveira V, Thacker BE, Juliano MA, Pasqualini R, Arap W, Tersariol IL, Nader HB, Esko JD, Pinhal MA., Free PMC Article | 04/16/2011 |
| the expression of the NDST-1 isoform was approximately equal at all stages of mast cell maturation | Mast cell differentiation and activation is closely linked to expression of genes coding for the serglycin proteoglycan core protein and a distinct set of chondroitin sulfate and heparin sulfotransferases.
Duelli A, Rönnberg E, Waern I, Ringvall M, Kolset SO, Pejler G. | 01/21/2010 |
| effect of targeted inactivation of the Ndst1 gene on the inflammatory response associated with allergic inflammation | Deficiency of endothelial heparan sulfates attenuates allergic airway inflammation.
Zuberi RI, Ge XN, Jiang S, Bahaie NS, Kang BN, Hosseinkhani RM, Frenzel EM, Fuster MM, Esko JD, Rao SP, Sriramarao P., Free PMC Article | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesAssociation of genetic variants with hemorrhagic stroke in Japanese individuals.
Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.
Oguri M, Kato K, Yokoi K, Yoshida T, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y. Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.
Drenos F, Talmud PJ, Casas JP, Smeeth L, Palmen J, Humphries SE, Hingorani AD. | 04/22/2009 |
| Altered expression of NDST-1 mRNA in glomerular basement membrane in puromycin aminonucleoside nephrosis. | Altered expression of NDST-1 messenger RNA in puromycin aminonucleoside nephrosis.
Nakayama K, Natori Y, Sato T, Kimura T, Sugiura A, Sato H, Saito T, Ito S, Natori Y. | 01/21/2010 |