| Association of polymorphisms of HSD11B1 and ACE genes with trachoma disease. | Association of polymorphisms of HSD11B1 and ACE genes with trachoma disease.
Valdez-Velazquez LL, Ochoa-Díaz-López H, Delgado-Enciso I, Rangel-Villalobos H, Rodríguez-Sánchez IP, García-Miranda R, Velázquez-Ramírez DD, Reyes-Méndez NA, Barajas-Saucedo CE, Martínez-Fierro ML. | 08/30/2024 |
| 11-beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) gene expression in muscle is linked to reduced skeletal muscle index in sarcopenic patients. | 11-beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) gene expression in muscle is linked to reduced skeletal muscle index in sarcopenic patients.
Schluessel S, Zhang W, Nowotny H, Bidlingmaier M, Hintze S, Kunz S, Martini S, Mehaffey S, Meinke P, Neuerburg C, Schmidmaier R, Schoser B, Reisch N, Drey M., Free PMC Article | 01/10/2024 |
| G6PC1 and G6PC2 influence G6P flux but not HSD11B1 activity. | G6PC1 and G6PC2 influence G6P flux but not HSD11B1 activity.
Hawes EM, Boortz KA, Oeser JK, O'Rourke ML, O'Brien RM., Free PMC Article | 10/30/2023 |
| Hyperglycemia-activated 11beta-hydroxysteroid dehydrogenase type 1 increases endoplasmic reticulum stress and skin barrier dysfunction. | Hyperglycemia-activated 11β-hydroxysteroid dehydrogenase type 1 increases endoplasmic reticulum stress and skin barrier dysfunction.
Lee YB, Hwang HJ, Kim E, Lim SH, Chung CH, Choi EH., Free PMC Article | 08/25/2023 |
| Inhibition of 11beta-hydroxysteroid dehydrogenase 1 relieves fibrosis through depolarizing of hepatic stellate cell in NASH. | Inhibition of 11β-hydroxysteroid dehydrogenase 1 relieves fibrosis through depolarizing of hepatic stellate cell in NASH.
Lee SY, Kim S, Choi I, Song Y, Kim N, Ryu HC, Lim JW, Kang HJ, Kim J, Seo HR., Free PMC Article | 12/17/2022 |
| Variants in HSD11B1 gene modulate susceptibility to diabetes kidney disease and to insulin resistance in type 1 diabetes. | Variants in HSD11B1 gene modulate susceptibility to diabetes kidney disease and to insulin resistance in type 1 diabetes.
Mori RC, Santos-Bezerra DP, Pelaes TS, Admoni SN, Perez RV, Monteiro MB, Machado CG, Queiroz MS, Machado UF, Correa-Giannella ML. | 03/19/2022 |
| Microenvironment-associated gene HSD11B1 may serve as a prognostic biomarker in clear cell renal cell carcinoma: a study based on TCGA, RTqPCR, Western blotting, and immunohistochemistry. | Microenvironment-associated gene HSD11B1 may serve as a prognostic biomarker in clear cell renal cell carcinoma: a study based on TCGA, RT‑qPCR, Western blotting, and immunohistochemistry.
Han D, Yu Z, Zhang H, Liu H, Wang B, Qian D., Free PMC Article | 02/19/2022 |
| Association between Selected Polymorphisms rs12086634, rs846910, rs4844880, rs3753519 of 11beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) and the Presence of Insulin Resistance in the Polish Population of People Living in Upper Silesia. | Association between Selected Polymorphisms rs12086634, rs846910, rs4844880, rs3753519 of 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) and the Presence of Insulin Resistance in the Polish Population of People Living in Upper Silesia.
Szweda-Gandor N, Śnit M, Grzeszczak W., Free PMC Article | 10/30/2021 |
| Lack of association of the 11 beta-hydroxysteroid dehydrogenase type 1 gene 25669dupA polymorphism with obesity and metabolic syndrome. | Lack of association of the 11 beta-hydroxysteroid dehydrogenase type 1 gene 25669dupA polymorphism with obesity and metabolic syndrome.
Kaitozis O, Anousakis-Vlachochristou N, Chalikias G, Synetos A, Latsios G, Papanas N, Toutouzas K, Tousoulis D, Papazoglou D. | 09/18/2021 |
| The rise in expression and activity of 11beta-HSD1 in human mesenchymal progenitor cells induces adipogenesis through increased local cortisol synthesis. | The rise in expression and activity of 11β-HSD1 in human mesenchymal progenitor cells induces adipogenesis through increased local cortisol synthesis.
Blaschke M, Koepp R, Streit F, Beismann J, Manthey G, Seitz MT, Kragl A, Siggelkow H. | 08/28/2021 |
| Increased Expression of 11beta-Hydroxysteroid Dehydrogenase Type 1 Contributes to Epidermal Permeability Barrier Dysfunction in Aged Skin. | Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 Contributes to Epidermal Permeability Barrier Dysfunction in Aged Skin.
Kim BJ, Lee NR, Lee CH, Lee YB, Choe SJ, Lee S, Hwang HJ, Kim E, Lavery GG, Shin KO, Park K, Choi EH., Free PMC Article | 06/26/2021 |
| Addressing the role of 11beta-hydroxysteroid dehydrogenase type 1 in the development of polycystic ovary syndrome and the putative therapeutic effects of its selective inhibition in a preclinical model. | Addressing the role of 11β-hydroxysteroid dehydrogenase type 1 in the development of polycystic ovary syndrome and the putative therapeutic effects of its selective inhibition in a preclinical model.
Li X, Hu S, Zhu Q, Yao G, Yao J, Li J, Wang Y, Ding Y, Qi J, Xu R, Zhao H, Zhu Z, Du Y, Sun K, Sun Y. | 06/26/2021 |
| Exploring the activity of the enzyme 11beta-hydroxylase in the polycystic ovary syndrome. | Exploring the activity of the enzyme 11β-hydroxylase in the polycystic ovary syndrome.
Freitas de Medeiros S, Angelo LCA, Souto de Medeiros MA, Barbosa BB, Yamamoto MMW. | 06/5/2021 |
| Association of 11beta-hydroxysteroid dehydrogenase type1 (HSD11b1) gene polymorphisms with outcome of antidepressant therapy and suicide attempts. | Association of 11β-hydroxysteroid dehydrogenase type1 (HSD11b1) gene polymorphisms with outcome of antidepressant therapy and suicide attempts.
Figaro-Drumond FV, Pereira SC, Menezes IC, von Werne Baes C, Coeli-Lacchini FB, Oliveira-Paula GH, Cleare AJ, Young AH, Tanus-Santos JE, Juruena MF, Lacchini R. | 05/29/2021 |
| The upregulation of 11beta-HSD1 in ovarian granulosa cells by cortisol and interleukin-1beta in polycystic ovary syndrome. | The upregulation of 11β-HSD1 in ovarian granulosa cells by cortisol and interleukin-1β in polycystic ovary syndrome.
Wu H, Zhu Q, Li X, He Y, Wang Y, Lu Y, Qi J, Ding Y, Li J, Xu R, Sun Y. | 05/29/2021 |
| 11betahydroxysteroid dehydrogenase1 is associated with the activation of hepatic stellate cells in the development of hepatic fibrosis. | 11β‑hydroxysteroid dehydrogenase‑1 is associated with the activation of hepatic stellate cells in the development of hepatic fibrosis.
Xiao W, Lu MH, Rong PF, Zhang HY, Gong J, Peng YQ, Gong HY, Liu ZG., Free PMC Article | 05/1/2021 |
| Influence of labor on direct and indirect determinants of placental 11beta-hydroxysteroid dehydrogenase activity. | Influence of labor on direct and indirect determinants of placental 11beta-hydroxysteroid dehydrogenase activity.
Huebner H, Heussner K, Ruebner M, Schmid M, Nadal J, Woelfle J, Hartner A, Menendez-Castro C, Rauh M, Beckmann MW, Kehl S, Fahlbusch FB., Free PMC Article | 03/20/2021 |
| Role of 11beta-hydroxysteroid dehydrogenase type 1 in the development of atopic dermatitis. | Role of 11β-hydroxysteroid dehydrogenase type 1 in the development of atopic dermatitis.
Lee NR, Kim BJ, Lee CH, Lee YB, Lee S, Hwang HJ, Kim E, Kim SH, Lee MG, Lee SE, Lavery GG, Choi EH., Free PMC Article | 03/6/2021 |
| 11beta hydroxysteroid dehydrogenase 1: a new marker for predicting response to immune-checkpoint blockade therapy in non-small-cell lung carcinoma. | 11β hydroxysteroid dehydrogenase 1: a new marker for predicting response to immune-checkpoint blockade therapy in non-small-cell lung carcinoma.
Saito R, Miki Y, Abe T, Miyauchi E, Abe J, Nanamiya R, Inoue C, Sato I, Sasano H., Free PMC Article | 02/20/2021 |
| Haplotypes 1 and 4 of GR and a polymorphism of the HSD11B1 gene were associated with clinically relevant inflammatory and metabolic outcomes in ANCA-associated vasculitis. | Clinical outcome in anti-neutrophil cytoplasmic antibody-associated vasculitis and gene variants of 11β-hydroxysteroid dehydrogenase type 1 and the glucocorticoid receptor.
Hessels AC, Tuin J, Sanders JSF, Huitema MG, van Rossum EFC, Koper JW, van Beek AP, Stegeman CA, Rutgers A. | 01/11/2020 |
| 11beta-HSD1 and 11beta-HSD2 interconvert C11-keto and 11beta-hydroxy C19 and C21 steroids. | 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro.
Gent R, du Toit T, Swart AC. | 11/23/2019 |
| 11-beta-HSD1 has a larger Km and lower Vmax for the C19 and C21 C11-keto steroids. | The 11β-hydroxysteroid dehydrogenase isoforms: pivotal catalytic activities yield potent C11-oxy C(19) steroids with 11βHSD2 favouring 11-ketotestosterone, 11-ketoandrostenedione and 11-ketoprogesterone biosynthesis.
Gent R, du Toit T, Bloem LM, Swart AC. | 11/23/2019 |
| The formation of 7-keto,25-hydroxycholesterol from 7-ketocholesterol by cholesterol 25-hydroxylase (CH25H) and further stereospecific oxoreduction to 7beta,25-dihydroxycholesterol by human and mouse 11-beta-HSD1 could be demonstrated. | Enzymatic interconversion of the oxysterols 7β,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11β-hydroxysteroid dehydrogenase type 1 and 2.
Beck KR, Kanagaratnam S, Kratschmar DV, Birk J, Yamaguchi H, Sailer AW, Seuwen K, Odermatt A. | 11/16/2019 |
| High 11beta Hydroxysteroid dehydrogenase - 1 expression is associated with type 2 diabetes mellitus. | 11β Hydroxysteroid dehydrogenase - 1 activity in type 2 diabetes mellitus: a comparative study.
Shukla R, Basu AK, Mandal B, Mukhopadhyay P, Maity A, Chakraborty S, Devrabhai PK., Free PMC Article | 06/8/2019 |
| In human skin, either with or without atopic dermatitis (AD), there was negative correlation between the staining intensity of HSD11beta1 and ARTN. The mechanism of skin sensitivity in AD could be explained partly by decreased HSD11beta1 expression and subsequent ARTN overexpression. | Attenuated Activation of Homeostatic Glucocorticoid in Keratinocytes Induces Alloknesis via Aberrant Artemin Production.
Matsumoto A, Murota H, Terao M, Katayama I. | 05/25/2019 |