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    HLA-G major histocompatibility complex, class I, G [ Homo sapiens (human) ]

    Gene ID: 3135, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The Immune Modulation HLA-G*01:01:01 Full Allele Is Associated with Gastric Adenocarcinoma Development.

    The Immune Modulation HLA-G*01:01:01 Full Allele Is Associated with Gastric Adenocarcinoma Development.
    Suarez-Trujillo F, Juarez I, Vaquero-Yuste C, Gutierrez-Calvo A, Lopez-García A, Lasa I, Gomez R, Martin-Villa JM, Arnaiz-Villena A., Free PMC Article

    10/23/2024
    PGRMC2 and HLA-G regulate immune homeostasis in a microphysiological model of human maternal-fetal membrane interface.

    PGRMC2 and HLA-G regulate immune homeostasis in a microphysiological model of human maternal-fetal membrane interface.
    Lintao RCV, Richardson LS, Kammala AK, Chapa J, Yunque-Yap DA, Khanipov K, Golovko G, Dalmacio LMM, Menon R., Free PMC Article

    08/26/2024
    LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis.

    LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis.
    Wang J, Chai Q, Lei Z, Wang Y, He J, Ge P, Lu Z, Qiang L, Zhao D, Yu S, Qiu C, Zhong Y, Li BX, Zhang L, Pang Y, Gao GF, Liu CH., Free PMC Article

    08/23/2024
    Hypoimmunogenic human iPSCs expressing HLA-G, PD-L1, and PD-L2 evade innate and adaptive immunity.

    Hypoimmunogenic human iPSCs expressing HLA-G, PD-L1, and PD-L2 evade innate and adaptive immunity.
    Tsuneyoshi N, Hosoya T, Takeno Y, Saitoh K, Murai H, Amimoto N, Tatsumi R, Watanabe S, Hasegawa Y, Kikkawa E, Goto K, Nishigaki F, Tamura K, Kimura H., Free PMC Article

    07/25/2024
    HLA-G isoforms, HLA-C allotype and their expressions differ between early abortus and placenta in relation to spontaneous abortions.

    HLA-G isoforms, HLA-C allotype and their expressions differ between early abortus and placenta in relation to spontaneous abortions.
    Bora M, Singha S, Madan T, Deka G, Hazarika SG, Baruah S.

    04/12/2024
    HLA-G Expression/Secretion and T-Cell Cytotoxicity in Missed Abortion in Comparison to Normal Pregnancy.

    HLA-G Expression/Secretion and T-Cell Cytotoxicity in Missed Abortion in Comparison to Normal Pregnancy.
    Terzieva A, Alexandrova M, Manchorova D, Slavov S, Djerov L, Dimova T., Free PMC Article

    03/14/2024
    Association of human leukocyte antigen-G and -F with recurrent miscarriage and implantation failure: A systematic review and meta-analysis.

    Association of human leukocyte antigen-G and -F with recurrent miscarriage and implantation failure: A systematic review and meta-analysis.
    Han N, Xia W, Zhu C, Zhang X, Wang F, Yin Z, Zeng Q.

    03/13/2024
    [Research progress on HLA-G in non-small cell lung cancer].

    [Research progress on HLA-G in non-small cell lung cancer].
    Li R, Guo Z, Zhang X, Xiao L.

    03/1/2024
    IDO-1 impairs antitumor immunity of natural killer cells in triple-negative breast cancer via up-regulation of HLA-G.

    IDO-1 impairs antitumor immunity of natural killer cells in triple-negative breast cancer via up-regulation of HLA-G.
    Jing R, Bai S, Zhang P, Ren H, Jia L, Li W, Zheng G., Free PMC Article

    01/9/2024
    HLA-G alleles and their impacts on placental HSV-1 infection in women from southern Brazil.

    HLA-G alleles and their impacts on placental HSV-1 infection in women from southern Brazil.
    Tornatore M, Amaral SC, Alves BM, de Oliveira GR, Finger-Jardim F, Avila EC, Pivato AF, Lobato RC, Chies JAB, Ellwanger JH, Soares EA, Sánchez-Luquez K, Gonçalves CV, Martínez AMB, Soares MA, da Hora VP.

    09/18/2023
    Human leukocyte antigen-G 14 bp insertion/deletion polymorphism contributes to preeclampsia risk in Asian population: A systematic review and meta-analysis.

    Human leukocyte antigen-G 14 bp insertion/deletion polymorphism contributes to preeclampsia risk in Asian population: A systematic review and meta‑analysis.
    Meng Y, Liu J, Ji C, Zhang R, Hua Z, Chen J, Wang H, Wan S, Gao S, Yang X.

    09/15/2023
    Opposing impacts of HLA-G haplotypes PROMO-G010104-UTR-3 and PROMO-G010101b/c-UTR-4 on risk of recurrent implantation failure.

    Opposing impacts of HLA-G haplotypes PROMO-G010104-UTR-3 and PROMO-G010101b/c-UTR-4 on risk of recurrent implantation failure.
    Papúchová H, Saxtorph MH, Hallager T, Jepsen IE, Eriksen JO, Persson G, Funck T, Weisdorf I, Macklon N, Larsen LG, Hviid TVF.

    09/12/2023
    HLA-G 3'UTR haplotype analyses in HCV infection and HCV-derived cirrhosis, hepatocellular carcinoma and fibrosis.

    HLA-G 3'UTR haplotype analyses in HCV infection and HCV-derived cirrhosis, hepatocellular carcinoma and fibrosis.
    Oliveira Correa JD, Zambra FMB, Michita RT, Álvares-da-Silva MR, Simon D, Chies JAB.

    09/11/2023
    The Molecular Mechanisms of HLA-G Regulatory Function on Immune Cells during Early Pregnancy.

    The Molecular Mechanisms of HLA-G Regulatory Function on Immune Cells during Early Pregnancy.
    Mao J, Feng Y, Zhu X, Ma F., Free PMC Article

    08/28/2023
    Role of the HLA-G regulatory region polymorphisms in idiopathic recurrent spontaneous abortions (RSA).

    Role of the HLA-G regulatory region polymorphisms in idiopathic recurrent spontaneous abortions (RSA).
    Marik B, Nomani K, Agarwal N, Dadhwal V, Sharma A.

    07/27/2023
    Peripheral HLA-G/ILT-2 immune checkpoint axis in acute and convalescent COVID-19 patients.

    Peripheral HLA-G/ILT-2 immune checkpoint axis in acute and convalescent COVID-19 patients.
    Rohn H, Schramm S, Pansikaki K, Jansen S, Hendriks C, Platte M, Konik MJ, Dolff S, Wilde B, Kordelas L, Trilling M, Krawczyk A, Horn PA, Witzke O, Rebmann V., Free PMC Article

    07/21/2023
    Dynamic changes of soluble HLA-G and cytokine plasma levels in cervical cancer patients: potential role in cancer progression and immunotherapy.

    Dynamic changes of soluble HLA-G and cytokine plasma levels in cervical cancer patients: potential role in cancer progression and immunotherapy.
    Xu HH, Xie YY, Jun-Gan, Yang Z, Han QY., Free PMC Article

    07/20/2023
    HLA-G susceptibility to hepatitis B infection and related hepatocellular carcinoma in the Japanese population.

    HLA-G susceptibility to hepatitis B infection and related hepatocellular carcinoma in the Japanese population.
    Okumura T, Joshita S, Yamazaki T, Iwadare T, Wakabayashi SI, Kobayashi H, Yamashita Y, Sugiura A, Kimura T, Ota M, Umemura T.

    07/17/2023
    [Correlation between Serum Interleukin-33, beta2-Microglobulin Levels and DS Stage in Patients with Multiple Myeloma].

    [Correlation between Serum Interleukin-33, β(2)-Microglobulin Levels and DS Stage in Patients with Multiple Myeloma].
    Wang SY, Qiu DB, Fan CH.

    06/29/2023
    The Upregulation of HLA-G1 and miRNA-34a in Lens Epithelial Cells of Diabetic Retinopathy Patients.

    The Upregulation of HLA-G1 and miRNA-34a in Lens Epithelial Cells of Diabetic Retinopathy Patients.
    Taghvaei-Bijandi E, Abedian F, Ahmadzadeh Amiri A, Jafari N, Abediankenari S.

    06/3/2023
    KIR2DL4/HLA-G polymorphisms were associated with HCV infection susceptibility among Chinese high-risk population.

    KIR2DL4/HLA-G polymorphisms were associated with HCV infection susceptibility among Chinese high-risk population.
    Feng Z, Huang P, Zhang J, Xia X, Zhang AM, Zeng T, Chen Q, Zhu C, Tan W, Zhang Y, Yue M.

    03/30/2023
    The + 3010/C single nucleotide polymorphism (rs1710) at the HLA-G 3' untranslated region is associated with a short transcript exhibiting a deletion of 92 nucleotides.

    The + 3010/C single nucleotide polymorphism (rs1710) at the HLA-G 3' untranslated region is associated with a short transcript exhibiting a deletion of 92 nucleotides.
    Castelli EC, Paes GS, da Silva IM, Moreau P, Donadi EA.

    03/28/2023
    The association between genetic variants at 3'-UTR and 5'-URR of HLA-G gene and the clinical outcomes of patients with leukemia receiving hematopoietic stem cell transplantation.

    The association between genetic variants at 3'-UTR and 5'-URR of HLA-G gene and the clinical outcomes of patients with leukemia receiving hematopoietic stem cell transplantation.
    Chen DP, Wang PN, Hour AL, Lin WT, Hsu FP, Wang WT, Tseng CP., Free PMC Article

    03/16/2023
    Evidence for Epistatic Interaction between HLA-G and LILRB1 in the Pathogenesis of Nonsegmental Vitiligo.

    Evidence for Epistatic Interaction between HLA-G and LILRB1 in the Pathogenesis of Nonsegmental Vitiligo.
    Oliveira-Caramez ML, Veiga-Castelli L, Souza AS, Cardili RN, Courtin D, Flória-Santos M, Donadi E, Giuliatti S, Sabbagh A, Castelli EC, Mendes-Junior CT., Free PMC Article

    03/2/2023
    HLA-G 5'URR regulatory polymorphisms are associated with the risk of developing gliomas.

    HLA-G 5'URR regulatory polymorphisms are associated with the risk of developing gliomas.
    Durmanova V, Kluckova K, Filova B, Minarik G, Kozak J, Rychly B, Svajdler M, Matejcik V, Steno J, Bucova M.

    03/2/2023
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