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    NRG1 neuregulin 1 [ Homo sapiens (human) ]

    Gene ID: 3084, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The role and mechanism of NRG1/ErbB4 in inducing the differentiation of induced pluripotent stem cells into cardiomyocytes.

    The role and mechanism of NRG1/ErbB4 in inducing the differentiation of induced pluripotent stem cells into cardiomyocytes.
    Li X, Zhang H, Li W, Tuo H, He B, Jiang H., Free PMC Article

    10/20/2024
    Neuregulin 1 mitigated prolactin deficiency through enhancing TRPM8 signaling under the influence of melatonin in senescent pituitary lactotrophs.

    Neuregulin 1 mitigated prolactin deficiency through enhancing TRPM8 signaling under the influence of melatonin in senescent pituitary lactotrophs.
    Zhang W, Dao JJ, Li Q, Liu C, Qiao CM, Cui C, Shen YQ, Zhao WJ.

    08/20/2024
    NRG1 regulates Fra-1 transcription and metastasis of triple-negative breast cancer cells via the c-Myc ubiquitination as manipulated by ERK1/2-mediated Fbxw7 phosphorylation.

    NRG1 regulates Fra-1 transcription and metastasis of triple-negative breast cancer cells via the c-Myc ubiquitination as manipulated by ERK1/2-mediated Fbxw7 phosphorylation.
    Shu L, Chen A, Li L, Yao L, He Y, Xu J, Gu W, Li Q, Wang K, Zhang T, Liu G.

    07/26/2024
    Myeloid Cell-Derived IL-1 Signaling Damps Neuregulin-1 from Fibroblasts to Suppress Colitis-Induced Early Repair of the Intestinal Epithelium.

    Myeloid Cell-Derived IL-1 Signaling Damps Neuregulin-1 from Fibroblasts to Suppress Colitis-Induced Early Repair of the Intestinal Epithelium.
    Qiu D, Xu S, Ji K, Tang C., Free PMC Article

    05/7/2024
    Identification and validation of CRLF1 and NRG1 as immune-related signatures in hypertrophic scar.

    Identification and validation of CRLF1 and NRG1 as immune-related signatures in hypertrophic scar.
    Yu B, Cao Y, Li S, Bai R, Zhou G, Fu Q, Liang L, Gu W, Zhang L, Chen M.

    03/26/2024
    Neuregulin-1 and ALS19 (ERBB4): at the crossroads of amyotrophic lateral sclerosis and cancer.

    Neuregulin-1 and ALS19 (ERBB4): at the crossroads of amyotrophic lateral sclerosis and cancer.
    Adashek JJ, Pandya C, Maragakis NJ, De P, Cohen PR, Kato S, Kurzrock R., Free PMC Article

    03/21/2024
    Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma.

    Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma.
    Hosni S, Kilian V, Klümper N, Gabbia D, Sieckmann K, Corvino D, Winkler A, Saponaro M, Wörsdörfer K, Schmidt D, Hahn O, Zanotto I, Bertlich M, Toma M, Bald T, Eckstein M, Hölzel M, Geyer M, Ritter M, Wachten D, De Martin S, Alajati A., Free PMC Article

    03/6/2024
    The involvement of Neuregulin-1 in the process of facial nerve injury repair through the utilization of dental pulp stem cells.

    The involvement of Neuregulin-1 in the process of facial nerve injury repair through the utilization of dental pulp stem cells.
    Yao L, Xu W, Liu L, Xu X, Xi H, Xue B, Cao X, Lin S, Piao G, Sun J, Wang X., Free PMC Article

    02/21/2024
    Diagnostic potential of NRG1 in benign nerve sheath tumors and its influence on the PI3K-Akt signaling and tumor immunity.

    Diagnostic potential of NRG1 in benign nerve sheath tumors and its influence on the PI3K-Akt signaling and tumor immunity.
    Yan S, Zhao J, Gao P, Li Z, Li Z, Liu X, Wang P., Free PMC Article

    02/14/2024
    Neuregulin 1 as a potential biomarker for disease progression in moyamoya disease: A case-control study in Chinese population.

    Neuregulin 1 as a potential biomarker for disease progression in moyamoya disease: A case-control study in Chinese population.
    Chen J, Zheng H, Wu X, Niu X, Dai Y, Zhou Z, Ye F.

    02/14/2024
    Serum neuregulin 1 in relation to ventricular function and subclinical atherosclerosis in type 2 diabetes patients.

    Serum neuregulin 1 in relation to ventricular function and subclinical atherosclerosis in type 2 diabetes patients.
    Eldin AS, Fawzy O, Mahmoud E, Elaziz OHA, Enayet AEA, Khidr EG.

    01/11/2024
    NRG1 promotes tumorigenesis and metastasis and afatinib treatment efficiency is enhanced by NRG1 inhibition in esophageal squamous cell carcinoma.

    NRG1 promotes tumorigenesis and metastasis and afatinib treatment efficiency is enhanced by NRG1 inhibition in esophageal squamous cell carcinoma.
    Hou G, Niu T, Jia A, Zhang Y, Chen X, Wei H, Jia Y, Xu Y, Li Y, Wang P, Chatterjee A.

    12/6/2023
    Is neuregulin-1 (NRG-1) a potential blood biomarker linking depression to obesity? A case-control study.

    Is neuregulin-1 (NRG-1) a potential blood biomarker linking depression to obesity? A case-control study.
    Abdelaziz HA, Abdelbaki TN, Dean YE, Assem S., Free PMC Article

    09/20/2023
    Boosting neuregulin 1 type-III expression hastens SMA motor axon maturation.

    Boosting neuregulin 1 type-III expression hastens SMA motor axon maturation.
    Kong L, Hassinan CW, Gerstner F, Buettner JM, Petigrow JB, Valdivia DO, Chan-Cortés MH, Mistri A, Cao A, McGaugh SA, Denton M, Brown S, Ross J, Schwab MH, Simon CM, Sumner CJ., Free PMC Article

    08/10/2023
    RNA Sequencing Identifies Novel NRG1 Fusions in Solid Tumors that Lack Co-Occurring Oncogenic Drivers.

    RNA Sequencing Identifies Novel NRG1 Fusions in Solid Tumors that Lack Co-Occurring Oncogenic Drivers.
    Severson E, Achyut BR, Nesline M, Pabla S, Previs RA, Kannan G, Chenn A, Zhang S, Klein R, Conroy J, Sausen M, Sathyan P, Saini KS, Ghosh A, Jensen TJ, Reddy P, Ramkissoon SH.

    06/26/2023
    Correlation of rs35753505 polymorphism in Neuregulin 1 gene with psychopathology and intelligence of people with schizophrenia.

    Correlation of rs35753505 polymorphism in Neuregulin 1 gene with psychopathology and intelligence of people with schizophrenia.
    Moradkhani A, Turki Jalil A, Mahmood Saleh M, Vanaki E, Daghagh H, Daghighazar B, Akbarpour Z, Ghahramani Almanghadim H.

    04/26/2023
    Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth.

    Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth.
    Lemmetyinen TT, Viitala EW, Wartiovaara L, Kaprio T, Hagström J, Haglund C, Katajisto P, Wang TC, Domènech-Moreno E, Ollila S., Free PMC Article

    04/10/2023
    Patients with neuregulin 1 (NRG1) rearranged cancer are suitable for the theranostic approach and targeted therapy.

    Patients with neuregulin 1 (NRG1) rearranged cancer are suitable for the theranostic approach and targeted therapy.
    Ondič O, Ptáková N, Janovský V, Vančurová J, Hósová M, Michal M, Pešek M.

    03/19/2023
    Neuregulin-1 attenuates hemolysis- and ischemia induced-cerebrovascular inflammation associated with sickle cell disease.

    Neuregulin-1 attenuates hemolysis- and ischemia induced-cerebrovascular inflammation associated with sickle cell disease.
    Chambliss C, Stiles JK, Gee BE., Free PMC Article

    02/11/2023
    Association and epistatic analysis of white matter related genes across the continuum schizophrenia and autism spectrum disorders: The joint effect of NRG1-ErbB genes.

    Association and epistatic analysis of white matter related genes across the continuum schizophrenia and autism spectrum disorders: The joint effect of NRG1-ErbB genes.
    Prats C, Fatjó-Vilas M, Penzol MJ, Kebir O, Pina-Camacho L, Demontis D, Crespo-Facorro B, Peralta V, González-Pinto A, Pomarol-Clotet E, Papiol S, Parellada M, Krebs MO, Fañanás L.

    10/29/2022
    The Prognostic Value of Neuregulin-1beta in Heart Failure Patients With Preserved Ejection Fraction.

    The Prognostic Value of Neuregulin-1β in Heart Failure Patients With Preserved Ejection Fraction.
    Zhbanov KA, Shchendrygina AA, Salakheeva EY, Sokolova IY, Agadzhanyan AA, Zheleznykh EA, Zektser VY, Privalova EV, Belenkov YN.

    10/15/2022
    Elevated peripheral Neuregulin-1 protein levels in non-medicated focal epilepsy patients.

    Elevated peripheral Neuregulin-1 protein levels in non-medicated focal epilepsy patients.
    Zhao X, Huang G, Han Y, Xie Z, Zhu H, Gao Y, Tang W.

    07/16/2022
    Oncogenic Neuregulin 1 gene (NRG1) fusions in cancer: A potential new therapeutic opportunities.

    Oncogenic Neuregulin 1 gene (NRG1) fusions in cancer: A potential new therapeutic opportunities.
    Zhang C, Mei W, Zeng C.

    06/25/2022
    Neuregulin-1 regulates the conversion of M1/M2 microglia phenotype via ErbB4-dependent inhibition of the NF-kappaB pathway.

    Neuregulin-1 regulates the conversion of M1/M2 microglia phenotype via ErbB4-dependent inhibition of the NF-κB pathway.
    Ma Y, Fan P, Zhao R, Zhang Y, Wang X, Cui W.

    06/18/2022
    Effects of Oncogene Neuregulin 1 on Breast Cancer Cells.

    Effects of Oncogene Neuregulin 1 on Breast Cancer Cells.
    Li Q, Zhu B, Chen J, Wang H, Wu Y, Chen H, He X.

    06/11/2022
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