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    IL19 interleukin 19 [ Homo sapiens (human) ]

    Gene ID: 29949, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Highlighting allelic variations at the interleukin-19 locus in term of preeclampsia predisposing factors and access to an accurate diagnostic/screening option.

    Highlighting allelic variations at the interleukin-19 locus in term of preeclampsia predisposing factors and access to an accurate diagnostic/screening option.
    Parhoudeh S, Saadaty A, Khashei Varnamkhasti K, Khashei Varnamkhasti S, Naeimi L, Naeimi S., Free PMC Article

    12/18/2023
    Interleukin-19 is associated with severity and age-related phenotype of atopic dermatitis in children.

    Interleukin-19 is associated with severity and age-related phenotype of atopic dermatitis in children.
    Dumycz K, Kunkiel K, Stelmaszczyk-Emmel A, Józefczuk P, Adamiec A, Kulus M, Feleszko W.

    01/28/2023
    Upregulation of interleukin-19 in saliva of patients with COVID-19.

    Upregulation of interleukin-19 in saliva of patients with COVID-19.
    Saheb Sharif-Askari F, Saheb Sharif-Askari N, Hafezi S, Goel S, Ali Hussain Alsayed H, Ansari AW, Mahboub B, Al-Muhsen S, Temsah MH, Hamid Q, Halwani R., Free PMC Article

    10/8/2022
    Association between interleukin-19 gene polymorphisms and maternal puerperal infection.

    Association between interleukin-19 gene polymorphisms and maternal puerperal infection.
    Sang Z, Tan W, Wu H, Tian T, Li L.

    09/3/2022
    Comparison of TNF-alpha and IL-19 concentrations at different stages of breast cancer.

    Comparison of TNF-α and IL-19 concentrations at different stages of breast cancer.
    Mohammed AK., Free PMC Article

    08/27/2022
    Elevated IL-19 Serum Levels in Patients With Pernicious Anemia and Autoimmune Gastritis.

    Elevated IL-19 Serum Levels in Patients With Pernicious Anemia and Autoimmune Gastritis.
    Della Bella C, Antico A, Panozzo MP, Capitani N, Benagiano M, Petrone L, Azzurri A, Pratesi S, D'Elios S, Cianchi F, Ortiz-Princz D, Bizzaro N, D'Elios MM., Free PMC Article

    05/7/2022
    Interleukin19 gene polymorphism and its serum level in acne vulgaris patients.

    Interleukin19 gene polymorphism and its serum level in acne vulgaris patients.
    Bazid H, Marae A, Tayel N, Sleem R, Mahrous E, Mostafa MI, El Gayed EMA.

    03/19/2022
    IL-19 Contributes to the Development of Nonalcoholic Steatohepatitis by Altering Lipid Metabolism.

    IL-19 Contributes to the Development of Nonalcoholic Steatohepatitis by Altering Lipid Metabolism.
    Azuma YT, Fujita T, Izawa T, Hirota K, Nishiyama K, Ikegami A, Aoyama T, Ike M, Ushikai Y, Kuwamura M, Fujii H, Tsuneyama K., Free PMC Article

    01/22/2022
    Interleukin-17A Drives IL-19 and IL-24 Expression in Skin Stromal Cells Regulating Keratinocyte Proliferation.

    Interleukin-17A Drives IL-19 and IL-24 Expression in Skin Stromal Cells Regulating Keratinocyte Proliferation.
    Xu X, Prens E, Florencia E, Leenen P, Boon L, Asmawidjaja P, Mus AM, Lubberts E., Free PMC Article

    12/18/2021
    Osteocytes regulate neutrophil development through IL-19: a potent cytokine for neutropenia treatment.

    Osteocytes regulate neutrophil development through IL-19: a potent cytokine for neutropenia treatment.
    Xiao M, Zhang W, Liu W, Mao L, Yang J, Hu L, Zhang S, Zheng Y, Liu A, Song Q, Li Y, Xiao G, Zou Z, Bai X., Free PMC Article

    12/4/2021
    Assessment of serum interleukin-19 in acne vulgaris patients of different clinical severities.

    Assessment of serum interleukin-19 in acne vulgaris patients of different clinical severities.
    Saleh HM, Deif MA, El-Husseiny RM.

    09/25/2021
    IL-10 and Its Related Superfamily Members IL-19 and IL-24 Provide Parallel/Redundant Immune-Modulation in Loa loa Infection.

    IL-10 and Its Related Superfamily Members IL-19 and IL-24 Provide Parallel/Redundant Immune-Modulation in Loa loa Infection.
    Ricciardi A, Nutman TB., Free PMC Article

    09/11/2021
    Association of BCL2 polymorphisms and the IL19 single nucleotide polymorphism rs2243188 with systemic lupus erythematosus.

    Association of BCL2 polymorphisms and the IL19 single nucleotide polymorphism rs2243188 with systemic lupus erythematosus.
    Wang W, Wang X, Yang K, Fan Y., Free PMC Article

    06/5/2021
    IL-19 Up-Regulates Mucin 5AC Production in Patients With Chronic Rhinosinusitis via STAT3 Pathway.

    IL-19 Up-Regulates Mucin 5AC Production in Patients With Chronic Rhinosinusitis via STAT3 Pathway.
    Lai X, Li X, Chang L, Chen X, Huang Z, Bao H, Huang J, Yang L, Wu X, Wang Z, Bellanti JA, Zheng SG, Zhang G., Free PMC Article

    10/3/2020
    Our results show that polymorphisms in IFNgamma and IL19 genes significantly impacts in the probability of not achieving an optimal immune recovery in HIV-patients starting cART with CD4 T-cells <200cells/muL.

    CD4 recovery is associated with genetic variation in IFNγ and IL19 genes.
    García M, Jiménez-Sousa MA, Blanco J, Restrepo C, Pacheco YM, Brochado-Kith Ó, López-Bernaldo JC, Gutiérrez F, Portilla J, Estrada V, Górgolas M, Cabello A, Resino S, Benito JM, Rallón N, CoRIS and the Spanish HIV Biobank integrated in the Spanish AIDS Research Network Project RIS/EPICLIN 10_2015.

    08/1/2020
    Increased serum levels of HIF-1alpha and IL-19 correlated with the disease progression of COPD.

    Correlation of serum levels of HIF-1α and IL-19 with the disease progression of COPD: a retrospective study.
    Rong B, Liu Y, Li M, Fu T, Gao W, Liu H., Free PMC Article

    04/13/2019
    IL-19 was increased in the sera and skin of patients with cutaneous T-cell lymphoma and atopic dermatitis.

    Increased Interleukin-19 Expression in Cutaneous T-cell Lymphoma and Atopic Dermatitis.
    Oka T, Sugaya M, Takahashi N, Nakajima R, Otobe S, Kabasawa M, Suga H, Miyagaki T, Asano Y, Sato S.

    07/14/2018
    IL-19 is significantly positive correlated with UAE and Cystatin C. IL-19 may play an important role that contributes to the progression of diabetic nephropathy.

    The association between interleukin-19 concentration and diabetic nephropathy.
    Li L, Jiang XG, Hu JY, Yu ZQ, Xu JY, Liu F, Zhao GC, Zhang L, Gu HM, Zhang SJ, Meng J., Free PMC Article

    02/24/2018
    The authors identified highly significant associations with better melanoma overall survival for rs6673928, impacting IL19 expression (HR, 0.56; 95% CI, 0.41-0.77; P = 0.0002) and rs6695772, controlling the expression of BATF3 (HR, 1.64; 95% CI, 1.19-2.24; P = 0.0019).

    The Expression Quantitative Trait Loci in Immune Pathways and their Effect on Cutaneous Melanoma Prognosis.
    Vogelsang M, Martinez CN, Rendleman J, Bapodra A, Malecek K, Romanchuk A, Kazlow E, Shapiro RL, Berman RS, Krogsgaard M, Osman I, Kirchhoff T., Free PMC Article

    02/3/2018
    a set of IL-17A-regulated genes in keratinocytes, which recapitulate typical psoriasis genes exemplified by DEFB4A, S100A7, IL19 and CSF3, based on the differences in the expression profiles of cells stimulated with six cytokines versus cells stimulated with only five cytokines lacking IL-17A.

    IL-17A plays a central role in the expression of psoriasis signature genes through the induction of IκB-ζ in keratinocytes.
    Muromoto R, Hirao T, Tawa K, Hirashima K, Kon S, Kitai Y, Matsuda T.

    12/16/2017
    findings show that the expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis; microbial-driven expression of IL-19 by intestinal macrophages may contribute to the pathogenesis of inflammatory bowel disease

    The Stimulation of Macrophages with TLR Ligands Supports Increased IL-19 Expression in Inflammatory Bowel Disease Patients and in Colitis Models.
    Steinert A, Linas I, Kaya B, Ibrahim M, Schlitzer A, Hruz P, Radulovic K, Terracciano L, Macpherson AJ, Niess JH.

    10/28/2017
    The SNP of IL-19 rs1798 may be associated with susceptibility to hepatitis B in children.

    [Association between IL-19 gene polymorphisms and hepatitis B virus susceptibility in children].
    Fan J, Mu LH, Zhou L, Huang X, Huang YF., Free PMC Article

    06/3/2017
    The frequency of allele C in rs2243188 was lower in the SLE population.

    Analysis of interleukin 19 serum levels and single nucleotide polymorphisms in systemic lupus erythematosus.
    Lin JR, Qin HH, Wang Y, Liang J, Xu JH.

    02/18/2017
    These data are the first to implicate the association between the interleukin-19 and type 2 diabetes mellitus with vascular complications.

    Association between interleukin-19 and angiopoietin-2 with vascular complications in type 2 diabetes.
    Li L, ZHeng-Qing Y, Juan-Yu H, Jian-Yong X, Fan L, Guang-Chun Z, Lei Z, Hui-Ming G, Si-Jing Z, Meng J., Free PMC Article

    02/18/2017
    IL-19 and Ang-2 might be involved in angiogenesis of T2 Diabetes mellitus complications.

    Interleukin-19 and angiopoietin-2 can enhance angiogenesis of diabetic complications.
    Li L, Yu ZH, Qian L, Xu JY, Liu F, Zhao GC, Zhang L, Gu HM, Zhang SJ, Meng J.

    12/17/2016
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