| ChIP-seq analysis found IL21R, a target gene of GTF2I-the susceptibility gene for primary biliary cholangitis in Chinese Han. | ChIP-seq analysis found IL21R, a target gene of GTF2I-the susceptibility gene for primary biliary cholangitis in Chinese Han.
Wu Z, Li H, Xu H, Feng F, Zhang F, Zhang S, Wang L, Li Y. | 04/17/2024 |
| Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment. | Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment.
Adams JW, Vinokur A, de Souza JS, Austria C, Guerra BS, Herai RH, Wahlin KJ, Muotri AR., Free PMC Article | 04/2/2024 |
| GTF2I mutation in micronodular thymoma with lymphoid stroma. | GTF2I mutation in micronodular thymoma with lymphoid stroma.
Bille A, Fryer K, Wallace A, Nonaka D. | 01/26/2024 |
| Neuronal Gtf2i deletion alters mitochondrial and autophagic properties. | Neuronal Gtf2i deletion alters mitochondrial and autophagic properties.
Nir Sade A, Levy G, Schokoroy Trangle S, Elad Sfadia G, Bar E, Ophir O, Fischer I, Rokach M, Atzmon A, Parnas H, Rosenberg T, Marco A, Elroy Stein O, Barak B., Free PMC Article | 12/20/2023 |
| DUX4-r exerts a neomorphic activity that depends on GTF2I in acute lymphoblastic leukemia. | DUX4-r exerts a neomorphic activity that depends on GTF2I in acute lymphoblastic leukemia.
Campolungo D, Salomé M, Biferali B, Tascini AS, Gabellini D., Free PMC Article | 09/22/2023 |
| Significance of YAP1-MAML2 rearrangement and GTF2I mutation in the diagnosis and differential diagnosis of metaplastic thymoma. | Significance of YAP1-MAML2 rearrangement and GTF2I mutation in the diagnosis and differential diagnosis of metaplastic thymoma.
Wang M, Xu H, Han Q, Wang L., Free PMC Article | 09/8/2023 |
| Unique correlation between GTF2I mutation and spindle cell morphology in thymomas (type A and AB thymomas). | Unique correlation between GTF2I mutation and spindle cell morphology in thymomas (type A and AB thymomas).
Wells K, Lamrca A, Papaxoinis G, Wallace A, Quinn AM, Summers Y, Nonaka D. | 06/26/2023 |
| Identification and validation of immune related core transcription factors GTF2I in NAFLD. | Identification and validation of immune related core transcription factors GTF2I in NAFLD.
Zhang M, Zhang Y, Jiao X, Lai L, Qian Y, Sun B, Yang W., Free PMC Article | 02/14/2023 |
| GTF2I Mutation in Thymomas: Independence From Racial-Ethnic Backgrounds. An Indian/German Comparative Study. | GTF2I Mutation in Thymomas: Independence From Racial-Ethnic Backgrounds. An Indian/German Comparative Study.
Jain D, Guleria P, Singh V, Parshad R, Kumar S, Gaiser T, Kurz KS, Ott G, Porubsky S, Preissler G, Sauer CG, Schölch S, Ströbel P, Hielscher T, Marx A, Popovic ZV., Free PMC Article | 03/19/2022 |
| Sjogren's syndrome-associated SNPs increase GTF2I expression in salivary gland cells to enhance inflammation development. | Sjögren's syndrome-associated SNPs increase GTF2I expression in salivary gland cells to enhance inflammation development.
Shimoyama S, Nakagawa I, Jiang JJ, Matsumoto I, Chiorini JA, Hasegawa Y, Ohara O, Hasebe R, Ota M, Uchida M, Kamimura D, Hojyo S, Tanaka Y, Atsumi T, Murakami M., Free PMC Article | 02/5/2022 |
| Role of the multifunctional transcription factor TFII-I in DNA damage repair. | Role of the multifunctional transcription factor TFII-I in DNA damage repair.
Roy AL. | 10/23/2021 |
| Association of GTF2I, NFKB1, and TYK2 Regional Polymorphisms With Systemic Sclerosis in a Chinese Han Population. | Association of GTF2I, NFKB1, and TYK2 Regional Polymorphisms With Systemic Sclerosis in a Chinese Han Population.
Liu C, Yan S, Chen H, Wu Z, Li L, Cheng L, Li H, Li Y., Free PMC Article | 09/25/2021 |
| Multiomics data reveals the influences of myasthenia gravis on thymoma and its precision treatment. | Multiomics data reveals the influences of myasthenia gravis on thymoma and its precision treatment.
Ruan X, Lu X, Gao J, Jiang L, Zhu Y, Zhou Y, Meng J, Yan H, Yan F, Wang F. | 09/11/2021 |
| Binding of Gtf2i-beta/delta transcription factors to the ARMS2 gene leads to increased circulating HTRA1 in AMD patients and in vitro. | Binding of Gtf2i-β/δ transcription factors to the ARMS2 gene leads to increased circulating HTRA1 in AMD patients and in vitro.
Pan Y, Iejima D, Nakayama M, Suga A, Noda T, Kaur I, Das T, Chakrabarti S, Guymer RH, DeAngelis MM, Yamamoto M, Baird PN, Iwata T., Free PMC Article | 09/4/2021 |
| A small 7q11.23 microduplication involving GTF2I in a family with intellectual disability. | A small 7q11.23 microduplication involving GTF2I in a family with intellectual disability.
Pinelli M, Terrone G, Troglio F, Squeo GM, Cappuccio G, Imperati F, Pignataro P, Genesio R, Nitch L, Del Giudice E, Merla G, Testa G, Brunetti-Pierri N., Free PMC Article | 06/5/2021 |
| Gene of the month: GTF2I. | Gene of the month: GTF2I.
Nathany S, Tripathi R, Mehta A. | 01/9/2021 |
| TFII-I-mediated polymerase pausing antagonizes GLI2 induction by TGFbeta. | TFII-I-mediated polymerase pausing antagonizes GLI2 induction by TGFβ.
McCleary-Wheeler AL, Paradise BD, Almada LL, Carlson AJ, Marks DL, Vrabel A, Vera RE, Sigafoos AN, Olson RL, Fernandez-Zapico ME., Free PMC Article | 09/26/2020 |
| A significant genetic association in the variant rs117026326 of GTF2I and neuromyelitis optica spectrum disorder was observed in a Norther Han Chinese population. | The GTF2I rs117026326 polymorphism is associated with neuromyelitis optica spectrum disorder but not with multiple sclerosis in a Northern Han Chinese population.
Liang H, Gao W, Liu X, Liu J, Mao X, Yang M, Long X, Zhou Y, Zhang Q, Zhu J, Wang S, Jin T. | 06/20/2020 |
| TFII-I factors and the neural crest master regulator AP2alpha associate with the promoters of key genes important in the development of facial and dental structures. GTF2I and GTF2IRD1 are deleted in Williams-Beuren syndrome. | TFII-I and AP2α Co-Occupy the Promoters of Key Regulatory Genes Associated with Craniofacial Development.
Miranda P, Enkhmandakh B, Bayarsaihan D. | 10/12/2019 |
| A case-control study identified the involvement of GTF2I gene polymorphisms in development of systemic lupus erythematosus, particularly in renal involvement. | Association of GTF2I gene polymorphisms with renal involvement of systemic lupus erythematosus in a Chinese population.
Meng Y, He Y, Zhang J, Xie Q, Yang M, Chen Y, Wu Y., Free PMC Article | 08/17/2019 |
| demonstrate a marked prevalence of a thymoma-specific mutated oncogene, GTF2I | The Integrated Genomic Landscape of Thymic Epithelial Tumors.
Radovich M, Pickering CR, Felau I, Ha G, Zhang H, Jo H, Hoadley KA, Anur P, Zhang J, McLellan M, Bowlby R, Matthew T, Danilova L, Hegde AM, Kim J, Leiserson MDM, Sethi G, Lu C, Ryan M, Su X, Cherniack AD, Robertson G, Akbani R, Spellman P, Weinstein JN, Hayes DN, Raphael B, Lichtenberg T, Leraas K, Zenklusen JC, Cancer Genome Atlas Network, Fujimoto J, Scapulatempo-Neto C, Moreira AL, Hwang D, Huang J, Marino M, Korst R, Giaccone G, Gokmen-Polar Y, Badve S, Rajan A, Ströbel P, Girard N, Tsao MS, Marx A, Tsao AS, Loehrer PJ., Free PMC Article | 12/22/2018 |
| we identified largest-ever effect on Asian rheumatoid arthritis across human non-HLA regions at GTF2I by heterogeneity mapping followed by replication studies, and pinpointed a possible causal variant | Association-heterogeneity mapping identifies an Asian-specific association of the GTF2I locus with rheumatoid arthritis.
Kim K, Bang SY, Ikari K, Yoo DH, Cho SK, Choi CB, Sung YK, Kim TH, Jun JB, Kang YM, Suh CH, Shim SC, Lee SS, Lee J, Chung WT, Kim SK, Choe JY, Momohara S, Taniguchi A, Yamanaka H, Nath SK, Lee HS, Bae SC., Free PMC Article | 04/28/2018 |
| the frequency of GTF2I mutation is higher in more indolent TETs and correlated with better prognosis. | GTF2I mutation frequently occurs in more indolent thymic epithelial tumors and predicts better prognosis.
Feng Y, Lei Y, Wu X, Huang Y, Rao H, Zhang Y, Wang F. | 03/31/2018 |
| GTF2I/Gtf2i, its physiologic role in human disorders was relatively unknown until recently. Novel studies show that it is involved in an array of human diseases including neurocognitive disorders, systemic lupus erythematosus (SLE), and cancer. | Pathophysiology of TFII-I: Old Guard Wearing New Hats.
Roy AL., Free PMC Article | 02/10/2018 |
| the results reported here support a model whereby common genetic variation in GTF2I mediates human sociality and anxiety via effects on oxytocin reactivity. | The Williams syndrome prosociality gene GTF2I mediates oxytocin reactivity and social anxiety in a healthy population.
Procyshyn TL, Spence J, Read S, Watson NV, Crespi BJ., Free PMC Article | 02/3/2018 |