| MicroRNA-322-5p protects against myocardial infarction through targeting BTG2. | MicroRNA-322-5p protects against myocardial infarction through targeting BTG2.
Ruan Y, Meng S, Jia R, Cao X, Jin Z. | 07/9/2024 |
| The involvement of EGR1 in neuron apoptosis in the in vitro model of spinal cord injury via BTG2 up-regulation. | The involvement of EGR1 in neuron apoptosis in the in vitro model of spinal cord injury via BTG2 up-regulation.
Wu F, Zhang P, Zhou G. | 06/2/2023 |
| Btg1 and Btg2 regulate neonatal cardiomyocyte cell cycle arrest. | Btg1 and Btg2 regulate neonatal cardiomyocyte cell cycle arrest.
Velayutham N, Calderon MU, Alfieri CM, Padula SL, van Leeuwen FN, Scheijen B, Yutzey KE., Free PMC Article | 05/17/2023 |
| Btg2 mutation induces renal injury and impairs blood pressure control in female rats. | Btg2 mutation induces renal injury and impairs blood pressure control in female rats.
Hoffman MJ, Takizawa A, Jensen ES, Schilling R, Grzybowski M, Geurts AM, Dwinell MR., Free PMC Article | 06/25/2022 |
| Icariside II protects cardiomyocytes from hypoxiainduced injury by upregulating the miR75p/BTG2 axis and activating the PI3K/Akt signaling pathway. | Icariside II protects cardiomyocytes from hypoxia‑induced injury by upregulating the miR‑7‑5p/BTG2 axis and activating the PI3K/Akt signaling pathway.
Hu D, Gu Y, Wu D, Zhang J, Li Q, Luo J, Li S, Yuan Z, Zhu B., Free PMC Article | 07/3/2021 |
| PC3/Tis21 associates with HDAC1, HDAC4, and HDAC9 in vivo, in fibroblast cells. | HDAC1, HDAC4, and HDAC9 Bind to PC3/Tis21/Btg2 and Are Required for Its Inhibition of Cell Cycle Progression and Cyclin D1 Expression.
Micheli L, D'Andrea G, Leonardi L, Tirone F. | 05/20/2017 |
| B-cell translocation gene 2 (BTG2) is a crucial regulator in GLP-1-induced insulin gene expression and insulin secretion via upregulation of pancreatic duodenal homeobox-1 (PDX-1) in pancreatic beta-cells. | B-cell translocation gene 2 positively regulates GLP-1-stimulated insulin secretion via induction of PDX-1 in pancreatic β-cells.
Hwang SL, Kwon O, Kim SG, Lee IK, Kim YD., Free PMC Article | 10/26/2013 |
| These findings demonstrate the gonadotropin stimulation of Btg2 in the ovary and, the physical interaction of Btg2 with Ant2 in mitochondria. | B-cell translocation gene 2: expression in the rat ovary and potential association with adenine nucleotide translocase 2 in mitochondria.
Park JI, Kim SG, Baek MW, Park TJ, Lim IK, Seo YW, Chun SY. | 09/28/2013 |
| the present study provides us with a novel molecular mechanism of BTG2-mediated induction of hepatic gluconeogenesis and suggests that BTG2 plays an important role in hepatic glucose metabolism. | B-cell translocation gene-2 increases hepatic gluconeogenesis via induction of CREB.
Hwang SL, Kwon O, Lee SJ, Roh SS, Kim YD, Choi JH. | 03/30/2013 |
| Math1 was expressed on postnatal days 0 - 5 in rat greater epithelial ridge cells. | [Expression of three kinds of transcription factors in greater epithelial ridge cells of rat cochlear].
Zhang Y, Hu YY, Song W, Guo WW, Zhai SQ. | 03/12/2011 |
| These results suggest that PC3 is involved in the shift from proliferation to differentiation and maturation in the ganglion neurons of the rat cochlea. | PC3 is involved in the shift from proliferation to differentiation and maturation in spiral ganglion neurons.
Hayashida M, Minoda R, Shinmyo Y, Ohta K, Tanaka H, Yumoto E. | 03/15/2010 |
| PC3/Tis21/BTG2 promotes differentiation of neural cells and protects neurons from apoptosis. | PC3 potentiates NGF-induced differentiation and protects neurons from apoptosis.
Corrente G, Guardavaccaro D, Tirone F, Corrente G, Guardavaccaro D, Tirone F, Corrente G, Guardavaccaro D, Tirone F. | 12/23/2009 |
| PC3/Tis21/BTG2 is a tumor suppressor of medulloblastoma | Inhibition of medulloblastoma tumorigenesis by the antiproliferative and pro-differentiative gene PC3.
Farioli-Vecchioli S, Tanori M, Micheli L, Mancuso M, Leonardi L, Saran A, Ciotti MT, Ferretti E, Gulino A, Pazzaglia S, Tirone F, Farioli-Vecchioli S, Tanori M, Micheli L, Mancuso M, Leonardi L, Saran A, Ciotti MT, Ferretti E, Gulino A, Pazzaglia S, Tirone F, Farioli-Vecchioli S, Tanori M, Micheli L, Mancuso M, Leonardi L, Saran A, Ciotti MT, Ferretti E, Gulino A, Pazzaglia S, Tirone F. | 12/23/2009 |
| A rat PC3 gene expressed in transgenic mice may prevent medulloblastoma development by controlling cell cycle and promoting differentiation of cerebellar granule cell precursors. | Inhibition of medulloblastoma tumorigenesis by the antiproliferative and pro-differentiative gene PC3.
Farioli-Vecchioli S, Tanori M, Micheli L, Mancuso M, Leonardi L, Saran A, Ciotti MT, Ferretti E, Gulino A, Pazzaglia S, Tirone F, Farioli-Vecchioli S, Tanori M, Micheli L, Mancuso M, Leonardi L, Saran A, Ciotti MT, Ferretti E, Gulino A, Pazzaglia S, Tirone F, Farioli-Vecchioli S, Tanori M, Micheli L, Mancuso M, Leonardi L, Saran A, Ciotti MT, Ferretti E, Gulino A, Pazzaglia S, Tirone F. | 01/21/2010 |
| PC3/Tis21/BTG2 is essential for terminal differentiation of neural progenitors. Genetic ablation of PC3/Tis21/BTG2 impairs terminal differentiation and shortens G1 phase of cell cycle duration of neural progenitor cells. | Impaired terminal differentiation of hippocampal granule neurons and defective contextual memory in PC3/Tis21 knockout mice.
Farioli-Vecchioli S, Saraulli D, Costanzi M, Leonardi L, Cinà I, Micheli L, Nutini M, Longone P, Oh SP, Cestari V, Tirone F., Free PMC Article | 12/24/2009 |
| Overexpression of BTG1 or BTG2 arrested granulosa cells at the G0/G1 phase of the cell cycle and decreased cell apoptosis. | The B cell translocation gene (BTG) family in the rat ovary: hormonal induction, regulation, and impact on cell cycle kinetics.
Li F, Liu J, Park ES, Jo M, Curry TE Jr., Free PMC Article | 01/21/2010 |
| The gene PC3/Tis21/BTG2 binds the histone deacetylases HDAC4 and HDAC1 and, as detected by chromatin immunoprecipitation, associates directly to the cyclin D1 promoter where it is likely to recruit the histone deacetylases. | Inhibition of medulloblastoma tumorigenesis by the antiproliferative and pro-differentiative gene PC3.
Farioli-Vecchioli S, Tanori M, Micheli L, Mancuso M, Leonardi L, Saran A, Ciotti MT, Ferretti E, Gulino A, Pazzaglia S, Tirone F, Farioli-Vecchioli S, Tanori M, Micheli L, Mancuso M, Leonardi L, Saran A, Ciotti MT, Ferretti E, Gulino A, Pazzaglia S, Tirone F, Farioli-Vecchioli S, Tanori M, Micheli L, Mancuso M, Leonardi L, Saran A, Ciotti MT, Ferretti E, Gulino A, Pazzaglia S, Tirone F. | 10/7/2008 |
| A comprehensive review of the different properties of the gene BTG2/Tis21/PC3 | The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?
Tirone F. | 10/7/2008 |
| The gene BTG2/Tis21/PC3 inhibits cyclin D1 transcription and is a G1-S cell cycle phase checkpoint | Arrest of G(1)-S progression by the p53-inducible gene PC3 is Rb dependent and relies on the inhibition of cyclin D1 transcription.
Guardavaccaro D, Corrente G, Covone F, Micheli L, D'Agnano I, Starace G, Caruso M, Tirone F., Free PMC Article | 10/7/2008 |
| The gene BTG2/Tis21/PC3 induces the differentiation in vivo of cerebellar neural progenitors, acting on the transcription of the proneural gene Math1 | Dual control of neurogenesis by PC3 through cell cycle inhibition and induction of Math1.
Canzoniere D, Farioli-Vecchioli S, Conti F, Ciotti MT, Tata AM, Augusti-Tocco G, Mattei E, Lakshmana MK, Krizhanovsky V, Reeves SA, Giovannoni R, Castano F, Servadio A, Ben-Arie N, Tirone F., Free PMC Article | 10/7/2008 |
| The gene PC3/Tis21/BTG2 potentiates the NGF-induced neural differentiation in vitro | PC3 potentiates NGF-induced differentiation and protects neurons from apoptosis.
Corrente G, Guardavaccaro D, Tirone F, Corrente G, Guardavaccaro D, Tirone F, Corrente G, Guardavaccaro D, Tirone F. | 10/7/2008 |
| PC3 potentiates the induction of neuronal markers tyrosine hydroxylase and neurofilament 160 kDa protein, enhances nerve growth factor-induced differentiation and protects neurons from apoptosis. | PC3 potentiates NGF-induced differentiation and protects neurons from apoptosis.
Corrente G, Guardavaccaro D, Tirone F, Corrente G, Guardavaccaro D, Tirone F, Corrente G, Guardavaccaro D, Tirone F. | 01/21/2010 |
| The role of NO in the enteric system is discussed with respect to neuronal nitric oxide synthase expression in neurons associated with the gut and the nerve growth factor and its receptor, tyrosine kinase A expression in the lamina epithelialis. | Neuronal nitric oxide synthase and nerve growth factor expression in the enteric nervous system.
Thippeswamy T, McKay JS. | 01/21/2010 |
| BTG2(TIS21/PC3) expression promotes neuronal differentiation and that it is required for survival of terminally differentiated cells. | BTG2(TIS21/PC3) induces neuronal differentiation and prevents apoptosis of terminally differentiated PC12 cells.
el-Ghissassi F, Valsesia-Wittmann S, Falette N, Duriez C, Walden PD, Puisieux A. | 01/21/2010 |
| genes induced by FSH in rat Sertoli cells would also show hormonal regulation during rat folliculogenesis | Regulation of protein tyrosine phosphatase 4a1, B-cell translocation gene 2, nuclear receptor subfamily 4a1 and diacylglycerol O-acyltransferase 1 by follicle stimulating hormone in the rat ovary.
Schmidt J, de Avila J, McLean D. | 01/21/2010 |