| VPAC2 receptor mediates VIP-potentiated insulin secretion via ion channels in rat pancreatic beta cells. | VPAC2 receptor mediates VIP-potentiated insulin secretion via ion channels in rat pancreatic β cells.
Zhao X, Deng L, Ren L, Yang H, Wang B, Zhu X, Zhang X, Guo C, Zhang Y, Liu Y. | 02/11/2023 |
| PAC1, VPAC1, and VPAC2 Receptor Expression in Rat and Human Trigeminal Ganglia: Characterization of PACAP-Responsive Receptor Antibodies. | PAC(1), VPAC(1), and VPAC(2) Receptor Expression in Rat and Human Trigeminal Ganglia: Characterization of PACAP-Responsive Receptor Antibodies.
Tasma Z, Siow A, Harris PWR, Brimble MA, O'Carroll SJ, Hay DL, Walker CS., Free PMC Article | 12/10/2022 |
| the protein and mRNA expression of pituitary adenylate cyclase-activating polypeptide-related receptors (PAC1, VPAC1, and VPAC2) in the trigeminal ganglia and trigeminal nucleus caudalis to identify changes associated with repetitive applications of chemical dural stimulations. | Chronic changes in pituitary adenylate cyclase-activating polypeptide and related receptors in response to repeated chemical dural stimulation in rats.
Han X, Ran Y, Su M, Liu Y, Tang W, Dong Z, Yu S., Free PMC Article | 05/5/2018 |
| In cultured rat conjunctival goblet cells, VPAC1 and 2 receptors are functional; VIP stimulates a cAMP-dependent increase in [Ca(2+)]i and glycoconjugate secretion, but not ERK1/2 activation. | Effect of VIP on intracellular [Ca2+], extracellular regulated kinase 1/2, and secretion in cultured rat conjunctival goblet cells.
Li D, Jiao J, Shatos MA, Hodges RR, Dartt DA., Free PMC Article | 06/22/2013 |
| Although cerebellar arteries expressed transcripts for all three PACAP receptor subtypes, middle meningeal arteries demonstrated only PAC1 and VPAC2 receptor expression. | Pituitary adenylate cyclase-activating polypeptide (PACAP) potently dilates middle meningeal arteries: implications for migraine.
Syed AU, Koide M, Braas KM, May V, Wellman GC., Free PMC Article | 04/20/2013 |
| both VPAC1 and VPAC2 could have roles at all stages of retinal development, that PACAP acts through a specific set of PAC1 isoforms, and that Hip and Hop1 are predominantly involved in the postnatal development of rat retina. | Development-related splicing regulates pituitary adenylate cyclase-activating polypeptide (PACAP) receptors in the retina.
Lakk M, Szabó B, Völgyi B, Gábriel R, Dénes V. | 01/26/2013 |
| Expression and distribution of vasoactive intestinal peptide receptor 2 remains unchanged in aged rat brains. | Region-specific changes in the immunoreactivity of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC2, and PAC1 receptor) in the aged rat brains.
Lee JC, Cho YJ, Kim J, Kim N, Kang BG, Cha CI, Joo KM. | 05/21/2011 |
| investigation of role of VPAC2 (& VPAC1) in pulmonary circulation in health/disease: distribution of VPAC2 (& VPAC1) in aorta/pulmonary artery (& smooth muscle cells); effects of VPAC antagonists on cell proliferation; dominant role of VPAC2 | Role of VPAC1 and VPAC2 in VIP mediated inhibition of rat pulmonary artery and aortic smooth muscle cell proliferation.
St Hilaire RC, Murthy SN, Kadowitz PJ, Jeter JR Jr. | 11/27/2010 |
| Involvement of VPAC1 and VPAC2 receptors in increasing local pancreatic blood flow in anesthetized rats. | Involvement of VPAC1 and VPAC2 receptors in increasing local pancreatic blood flow in anesthetized rats.
Igarashi H, Ito T, Kuwano-Kojima M, Takayanagi R, Coy DH, Jensen RT. | 01/21/2010 |
| inhibitory effect of pituitary adenylate cyclase-activating polypeptide on food intake may be mediated, at least in part, through modulation of neuropeptide Y neurotransmission | Expression of PACAP receptor mRNAs by neuropeptide Y neurons in the rat arcuate nucleus.
Mounien L, Bizet P, Boutelet I, Gourcerol G, Basille M, Gonzalez B, Vaudry H, Jegou S. | 01/21/2010 |
| VPAC2 receptor activation mediates vasoactive intestinal polypeptide enhancement of population spike amplitude in the hippocampus essentially through a protein kinase A-dependent mechanism | VPAC2 receptor activation mediates VIP enhancement of population spikes in the CA1 area of the hippocampus.
Cunha-Reis D, Ribeiro JA, Sebastião AM. | 01/21/2010 |
| all three PACAP/VIP receptor subtypes are expressed in primary rat adipocytes, but that the VPAC2-R subtype is responsible for mediating the lipolytic effects induced by PACAP38 and VIP. | VPAC2-R mediates the lipolytic effects of pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide in primary rat adipocytes.
Akesson L, Ahrén B, Edgren G, Degerman E. | 01/21/2010 |
| Aging reduces vasoactive intestinal peptide (VIP) receptor mRNA within the suprachiasmatic nucleus of aged male rats. A diurnal rhythm of VPAC2 receptor mRNA was present but reduced in the aged rats. | Ageing and the diurnal expression of mRNAs for vasoactive intestinal peptide and for the VPAC2 and PAC1 receptors in the suprachiasmatic nucleus of male rats.
Kalló I, Kalamatianos T, Piggins HD, Coen CW. | 01/21/2010 |
| Thus, spinal p38 and p42/44 MAP kinases are activated in neuropathic pain states by mechanisms involving VPAC2, NK2, NMDA receptors and glial cytokine production. | Activation of p38 and p42/44 MAP kinase in neuropathic pain: involvement of VPAC2 and NK2 receptors and mediation by spinal glia.
Garry EM, Delaney A, Blackburn-Munro G, Dickinson T, Moss A, Nakalembe I, Robertson DC, Rosie R, Robberecht P, Mitchell R, Fleetwood-Walker SM. | 01/21/2010 |
| Presence of vasoactive intestinal peptide (VIP) receptor 2 mRNA is demonstrated at sites putatively innervated by VIP-containing projections from the suprachiasmatic nucleus. | Expression of VIP and/or PACAP receptor mRNA in peptide synthesizing cells within the suprachiasmatic nucleus of the rat and in its efferent target sites.
Kalamatianos T, Kalló I, Piggins HD, Coen CW. | 01/21/2010 |