| GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4. | GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.
Chen Y, Feng Y, Lin Y, Zhou X, Wang L, Zhou Y, Lin K, Cai L., Free PMC Article | 03/6/2024 |
| Low GSTM3 expression is associated with poor disease-free survival in resected esophageal squamous cell carcinoma. | Low GSTM3 expression is associated with poor disease-free survival in resected esophageal squamous cell carcinoma.
Yang F, Wen J, Luo K, Fu J., Free PMC Article | 11/6/2021 |
| Glutathione S-Transferase M3 Is Associated with Glycolysis in Intrinsic Temozolomide-Resistant Glioblastoma Multiforme Cells. | Glutathione S-Transferase M3 Is Associated with Glycolysis in Intrinsic Temozolomide-Resistant Glioblastoma Multiforme Cells.
Cheng SY, Chen NF, Wen ZH, Yao ZK, Tsui KH, Kuo HM, Chen WF., Free PMC Article | 07/24/2021 |
| Whole-proteome analysis of mesonephric-derived cancers describes new potential biomarkers. | Whole-proteome analysis of mesonephric-derived cancers describes new potential biomarkers.
Gibbard E, Cochrane DR, Pors J, Negri GL, Colborne S, Cheng AS, Chow C, Farnell D, Tessier-Cloutier B, McAlpine JN, Morin GB, Schmidt D, Kommoss S, Kommoss F, Keul J, Gilks B, Huntsman DG, Hoang L. | 07/24/2021 |
| GSTM3 variant is a novel genetic modifier in Brugada syndrome, a disease with risk of sudden cardiac death. | GSTM3 variant is a novel genetic modifier in Brugada syndrome, a disease with risk of sudden cardiac death.
Juang JJ, Binda A, Lee SJ, Hwang JJ, Chen WJ, Liu YB, Lin LY, Yu CC, Ho LT, Huang HC, Chen CJ, Lu TP, Lai LC, Yeh SS, Lai LP, Chuang EY, Rivolta I, Antzelevitch C., Free PMC Article | 05/29/2021 |
| High GSTM3 expression is associated with glioma. | LncRNA GAS5 regulates the proliferation, migration, invasion and apoptosis of brain glioma cells through targeting GSTM3 expression. The effect of LncRNA GAS5 on glioma cells.
Li G, Cai Y, Wang C, Huang M, Chen J. | 12/21/2019 |
| this study indicated that a functional polymorphism of GSTM3 -rs1055259 reduced susceptibility of clear cell renal cell carcinoma in the Chinese population. It influenced GSTM3 protein synthesis by interfering miR-556 binding, subsequently suppressed ROS activity and clear cell renal cell carcinoma progression. . | A novel functional polymorphism of GSTM3 reduces clear cell renal cell carcinoma risk through enhancing its expression by interfering miR-556 binding.
Wang Y, Yang ZY, Chen YH, Li F, Shen H, Yu Y, Huang HY, Shen ZY., Free PMC Article | 11/30/2019 |
| ROS production is one mechanism by which cancer drugs kill tumour cells, and according to our evidence, GSTM3 may play an important role in preventing breast cancer treatment-induced cellular cytotoxicity | Oestrogen receptor-regulated glutathione S-transferase mu 3 expression attenuates hydrogen peroxide-induced cytotoxicity, which confers tamoxifen resistance on breast cancer cells.
Lin JH, Tu SH, Chen LC, Huang CC, Chang HL, Cheng TC, Chang HW, Wu CH, Wu HC, Ho YS. | 01/12/2019 |
| Differential activity of antioxidant enzymes caused by the polymorphism in GSTM3 may contribute to resistance to hormonal therapy through oxidative stress. The GSTM3 rs7483 polymorphism may be a promising biomarker for prostate cancer patients treated with androgen-deprivation therapy (ADT) | Gene polymorphisms in antioxidant enzymes correlate with the efficacy of androgen-deprivation therapy for prostate cancer with implications of oxidative stress.
Shiota M, Fujimoto N, Itsumi M, Takeuchi A, Inokuchi J, Tatsugami K, Yokomizo A, Kajioka S, Uchiumi T, Eto M. | 12/23/2017 |
| The individuals carrying the deletions of GSTM1 and GSTT1 were at risk for Neurocysticercosis (NCC). Genetic variants of GSTM3 and GSTP1 were not associated with NCC. | Human Glutathione S-Transferase Enzyme Gene Polymorphisms and Their Association With Neurocysticercosis.
Singh A, Prasad KN, Singh AK, Singh SK, Gupta KK, Paliwal VK, Pandey CM, Gupta RK. | 07/8/2017 |
| Expression of GSTM3 might be regulated by epigenetic changes in lens tissue. Hypermethylation in GSTM3 promoter and altered histone modification might have a role in the ARC formation. | Relationship Between the Altered Expression and Epigenetics of GSTM3 and Age-Related Cataract.
Li B, Zhou J, Zhang G, Wang Y, Kang L, Wu J, Chen J, Guan H. | 05/27/2017 |
| This meta-analysis suggested that the GSTT1 and GSTM3 polymorphisms might influence osteosarcoma risk. | The association of glutathione S-transferase polymorphisms in patients with osteosarcoma: evidence from a meta-analysis.
Wang Z, Xu H, He M, Wu H, Zhu Y, Su Z. | 11/12/2016 |
| No associations between the GSTT1, GSTP1, and GSTM3 genotypes and neoplasia risk were observed. In conclusion, we determined the genotype distribution of GST polymorphisms in control subjects and breast cancer patients from northeastern Mexico. | Polymorphisms in GSTM1, GSTT1, GSTP1, and GSTM3 genes and breast cancer risk in northeastern Mexico.
Jaramillo-Rangel G, Ortega-Martínez M, Cerda-Flores RM, Barrera-Saldaña HA. | 04/2/2016 |
| NSD1 interacted with RNAPII and bound to GSTM3 -63A/C TATA box. | Role of NSD1 in H2O2-induced GSTM3 suppression.
Chu G, Li Y, Dong X, Liu J, Zhao Y. | 08/8/2015 |
| To identify the genotypes of CYP1A1, GSTM1, GSTM3, GSTT1 and GSTP1 in a case-control study. | Susceptibility of lung cancer with polymorphisms of CYP1A1, GSTM1, GSTM3, GSTT1 and GSTP1 genotypes in the population of Inner Mongolia region.
Jiang XY, Chang FH, Bai TY, Lv XL, Wang MJ. | 04/11/2015 |
| All three markers correlated significantly with regional lymph node metastasis: FXYD3 (p = 0.0110), S100A11 (p = 0.0071), and GSTM3 (p = 0.0173) in colon cancer lymphatic metastasis. | Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer.
Meding S, Balluff B, Elsner M, Schöne C, Rauser S, Nitsche U, Maak M, Schäfer A, Hauck SM, Ueffing M, Langer R, Höfler H, Friess H, Rosenberg R, Walch A. | 01/10/2015 |
| This meta-analysis suggests that the GSTM3 A/B polymorphism may be an important protective factor for head and neck cancer, especially of laryngeal cancer and Caucasian populations. | GSTM3 A/B polymorphism and risk for head and neck cancer: a meta-analysis.
Xu Y, Wang J, Dong W., Free PMC Article | 09/13/2014 |
| rs1332018 genetic variants in the GSTM3 promoter predispose the host to downregulating GSTM3 expression in kidney, facilitate carcinogenesis, and predict an unfavourable postoperative prognosis of renal cell carcinoma. | Genetic variation in the GSTM3 promoter confer risk and prognosis of renal cell carcinoma by reducing gene expression.
Tan X, Wang Y, Han Y, Chang W, Su T, Hou J, Xu D, Yu Y, Ma W, Thompson TC, Cao G., Free PMC Article | 07/12/2014 |
| In conclusion, this epistatic interaction showed a high degree of consistency when stratifying by sex, the epsilon4 allele of apolipoprotein E genotype, and geographic region. | Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease.
Bullock JM, Medway C, Cortina-Borja M, Turton JC, Prince JA, Ibrahim-Verbaas CA, Schuur M, Breteler MM, van Duijn CM, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Hammond N, Combarros O, Mateo I, Warden DR, Lehmann MG, Belbin O, Brown K, Wilcock GK, Heun R, Kölsch H, Smith AD, Lehmann DJ, Morgan K. | 08/3/2013 |
| The GSTM3 A/B gene polymorphism is not associated with lung cancer susceptibility. | Lack of association of glutathione S-transferase M3 gene polymorphism with the susceptibility of lung cancer.
Feng X, Dong CQ, Shi JJ, Zhou HF, He W, Zheng BS. | 06/15/2013 |
| Methylation of GSTM3 promoter may contribute to oxidative stress-associated liver damage and correlate with the disease severity in Acute-on-chronic hepatitis B liver failure. | Methylation of the glutathione-S-transferase M3 gene promoter is associated with oxidative stress in acute-on-chronic hepatitis B liver failure.
Qi L, Zou ZQ, Wang LY, Gao S, Fan YC, Long B, Guo YM, Xu AL, Han J, Li T, Wang K. | 02/9/2013 |
| A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. | Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
Martins-de-Souza D, Guest PC, Mann DM, Roeber S, Rahmoune H, Bauder C, Kretzschmar H, Volk B, Baborie A, Bahn S. | 04/26/2012 |
| There were no significant differences in distribution of 3-bp deletion polymorphism in intron 6 variant allele in Glutathione-S-transferase M3 between chronic obstructive pulmonary disease patients and controls in a north Indian population. | Association of genetic polymorphism of GSTT1, GSTM1 and GSTM3 in COPD patients in a north Indian population.
Shukla RK, Kant S, Bhattacharya S, Mittal B. | 09/24/2011 |
| This study aims to investigate the genotype frequencies of GSTM1, GSTT1 and GSTM3 genes in 80 osteosarcoma patients and 160 normal control participants, and also the influence of these polymorphisms in the clinical outcome of osteosarcoma patients. | Glutathione S-transferase polymorphisms in osteosarcoma patients.
Salinas-Souza C, Petrilli AS, de Toledo SR. | 02/26/2011 |
| In individuals from Angola, Mozambique and the Sao Tome e Principe islands, the GSTM3*B allele was three times more frequent (0.74-0.78) than the GSTM3*A allele (0.22-0.26), with no significant differences in allele frequency across the three groups. | High prevalence of the GSTM3*A/B polymorphism in sub-Sarahan African populations.
Teixeira D, Vargens D, Príncipe A, Oliveira E, Amorim A, Prata MJ, Suarez-Kurtz G. | 02/5/2011 |