| Anti-tumor effect of PTEN and its effect on inhibition of the bone tumor through the CD47-SIRPalpha signaling pathway. | Anti-tumor effect of PTEN and its effect on inhibition of the bone tumor through the CD47-SIRPα signaling pathway.
Zhang Y, Hao J. | 02/1/2024 |
| Upregulated TSP1 and CD47 expression in the lung in nitrofen-induced congenital diaphragmatic hernia. | Upregulated TSP1 and CD47 expression in the lung in nitrofen-induced congenital diaphragmatic hernia.
Takayasu H. | 04/14/2023 |
| CD47 blocking antibody accelerates hematoma clearance and alleviates hydrocephalus after experimental intraventricular hemorrhage. | CD47 blocking antibody accelerates hematoma clearance and alleviates hydrocephalus after experimental intraventricular hemorrhage.
Ye F, Hua Y, Keep RF, Xi G, Garton HJL., Free PMC Article | 01/22/2022 |
| For the quantification of an anti-CD47 monoclonal antibody. | Two validated liquid chromatography-mass spectrometry methods with different pretreatments for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum compared with an electrochemiluminescence method.
Gao Y, Zhang D, Yang C, Duan X, Li X, Zhong D. | 02/1/2020 |
| The CD47 antibody or SiCD47 can protect cardiomyocytes against H/R injury through increasing autophagic flux and autophagic clearance. CD47 deficiency may offer a potential therapeutic approach for preventing myocardial I/R injury. | CD47 deficiency protects cardiomyocytes against hypoxia/reoxygenation injury by rescuing autophagic clearance.
Li Y, Zhao K, Zong P, Fu H, Zheng Y, Bao D, Yin Y, Chen Q, Lu L, Dai Y, Hou D, Kong X. | 08/31/2019 |
| Evidence linking the overexpression of TSP1-CD47 signaling in diabetes to a number of parameters associated with endothelial dysfunction including impaired angiogenesis, cellular senescence and a heightened state of oxidative stress was found. | Diabetes Impairs Angiogenesis and Induces Endothelial Cell Senescence by Up-Regulating Thrombospondin-CD47-Dependent Signaling.
Bitar MS., Free PMC Article | 06/29/2019 |
| down-regulation of CD47 exerts a protective effect against myocardial I/R injury, which may be attributable to attenuation of oxidative stress via activation of the eNOS/nitric oxide signaling pathway. | RNAi-Mediated Down-Regulation of CD47 Protects against Ischemia/Reperfusion-Induced Myocardial Damage via Activation of eNOS in a Rat Model.
Wang HB, Yang J, Ding JW, Chen LH, Li S, Liu XW, Yang CJ, Fan ZX, Yang J. | 02/18/2017 |
| Bone marrow mesenchymal stromal cells expression CD47/STAT1/STAT3 prevent isoproterenol induced myocardial fibrosis. | Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis.
Deng W, Chen QW, Li XS, Yuan ZM, Li GQ, Ke DZ, Wang L, Wu ZQ, Luo SL., Free PMC Article | 10/1/2016 |
| CD47 blockade with CD47mAb400 administered both to the donor and the recipient reduced liver graft ischemia reperfusion injury in a rat liver transplantation model. | CD47 blockade reduces ischemia/reperfusion injury and improves survival in a rat liver transplantation model.
Xiao ZY, Banan B, Jia J, Manning PT, Hiebsch RR, Gunasekaran M, Upadhya GA, Frazier WA, Mohanakumar T, Lin Y, Chapman WC., Free PMC Article | 12/26/2015 |
| IAP2 overexpression in neural stem cells induced neuronal differentiation. | Integrin-associated protein promotes neuronal differentiation of neural stem/progenitor cells.
Fujimura K, Niidome T, Shinozuka Y, Izumi Y, Kihara T, Sugimoto H, Akaike A, Kume T., Free PMC Article | 12/5/2015 |
| The CD47-binding peptide of thrombospondin-1 induces defenestration of liver sinusoidal endothelial cells. | The CD47-binding peptide of thrombospondin-1 induces defenestration of liver sinusoidal endothelial cells.
Venkatraman L, Tucker-Kellogg L., Free PMC Article | 04/5/2014 |
| These data reveal a novel role for CD47-mediated signaling in the control of the molecular network governing endothelial-dependent T-cell diapedesis. | Novel role of CD47 in rat microvascular endothelium: signaling and regulation of T-cell transendothelial migration.
Martinelli R, Newton G, Carman CV, Greenwood J, Luscinskas FW., Free PMC Article | 12/14/2013 |
| genetic induction of the expression of recipient CD47 on xenogeneic donor cells could provide inhibitory signals to recipient macrophages via SIPRalpha | Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPα inhibitory signaling in mice.
Teraoka Y, Ide K, Morimoto H, Tahara H, Ohdan H., Free PMC Article | 12/7/2013 |
| Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1. | Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1.
Csányi G, Yao M, Rodríguez AI, Al Ghouleh I, Sharifi-Sanjani M, Frazziano G, Huang X, Kelley EE, Isenberg JS, Pagano PJ., Free PMC Article | 02/2/2013 |
| Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1. | Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1.
Bauer PM, Bauer EM, Rogers NM, Yao M, Feijoo-Cuaresma M, Pilewski JM, Champion HC, Zuckerbraun BS, Calzada MJ, Isenberg JS., Free PMC Article | 09/22/2012 |
| Data suggest that hyperglycemia induces increase in association of IAP with SHPS-1 (tyrosine phosphatase non-receptor type substrate-1); this appears to be a generalized response of endothelial cells that contributes to endothelial cell dysfunction. | Disruption of the association of integrin-associated protein (IAP) with tyrosine phosphatase non-receptor type substrate-1 (SHPS)-1 inhibits pathophysiological changes in retinal endothelial function in a rat model of diabetes.
Maile LA, Gollahon K, Wai C, Byfield G, Hartnett ME, Clemmons D., Free PMC Article | 07/21/2012 |
| Data show that myelin down-regulates its own phagocytosis through CD47-SIRPalpha interactions. | Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes.
Gitik M, Liraz-Zaltsman S, Oldenborg PA, Reichert F, Rotshenker S., Free PMC Article | 06/4/2011 |
| CD47-SIRP-alpha interaction may be functionally important in cell-cell communication in the diseased glomerulus. | SIRP-alpha-CD47 system functions as an intercellular signal in the renal glomerulus.
Kurihara H, Harita Y, Ichimura K, Hattori S, Sakai T. | 09/27/2010 |
| Amyloid beta peptides trigger CD47-dependent mast cell secretory and phagocytic responses. | Amyloid beta peptides trigger CD47-dependent mast cell secretory and phagocytic responses.
Niederhoffer N, Levy R, Sick E, Andre P, Coupin G, Lombard Y, Gies JP. | 01/21/2010 |
| 4N1K-stimulated mast cell exocytosis involves a CD47/integrin/G(i) protein complex. | Activation of CD47 receptors causes histamine secretion from mast cells.
Sick E, Niederhoffer N, Takeda K, Landry Y, Gies JP., Free PMC Article | 01/21/2010 |
| IAP plays important roles in dendritic outgrowth and synaptic transmission in developing cortical neurons through the activation of MAPK | Neuronal roles of the integrin-associated protein (IAP/CD47) in developing cortical neurons.
Numakawa T, Ishimoto T, Suzuki S, Numakawa Y, Adachi N, Matsumoto T, Yokomaku D, Koshimizu H, Fujimori KE, Hashimoto R, Taguchi T, Kunugi H. | 01/21/2010 |